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In hypothalamic oligo\/amenorrhoeic women, baseline bone density has been shown to be significantly lower than that in healthy controls, therefore the decision to treat is clinically more important. The ideal formulation(s) and duration of treatment remain to be determined by further longitudinal and prospective randomised controlled trials in larger subject populations.<\/jats:p>","DOI":"10.1136\/bjsm.2005.020065","type":"journal-article","created":{"date-parts":[[2005,12,21]],"date-time":"2005-12-21T12:27:56Z","timestamp":1135168076000},"page":"11-24","source":"Crossref","is-referenced-by-count":118,"title":["Effect of oral contraceptives and hormone replacement therapy on bone mineral density in premenopausal and perimenopausal women: a systematic review"],"prefix":"10.1136","volume":"40","author":[{"given":"S L","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C M","family":"Lebrun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2005,12,21]]},"reference":[{"key":"2024051312360837000_40.1.11.1","first-page":"25","volume":"11","year":"2001","journal-title":"Health Rep"},{"key":"2024051312360837000_40.1.11.2","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1136\/bjsm.33.4.231","volume":"33","year":"1999","journal-title":"Br J Sports Med"},{"key":"2024051312360837000_40.1.11.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8545(05)70169-8"},{"key":"2024051312360837000_40.1.11.4","first-page":"1015","volume":"38","year":"1993","journal-title":"J Reprod Med"},{"key":"2024051312360837000_40.1.11.5","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-199307000-00003"},{"key":"2024051312360837000_40.1.11.6","first-page":"1","volume":"843","year":"1994","journal-title":"World Health Organ Tech Rep Ser"},{"key":"2024051312360837000_40.1.11.7","doi-asserted-by":"publisher","DOI":"10.1385\/JCD:7:1:17"},{"key":"2024051312360837000_40.1.11.8","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.36.1.10"},{"key":"2024051312360837000_40.1.11.9","first-page":"87","volume":"14","year":"2003","journal-title":"Adolesc Med"},{"key":"2024051312360837000_40.1.11.10","doi-asserted-by":"publisher","DOI":"10.1210\/er.23.3.279"},{"key":"2024051312360837000_40.1.11.11","doi-asserted-by":"publisher","DOI":"10.1126\/science.3388021"},{"key":"2024051312360837000_40.1.11.12","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.15.6613"},{"key":"2024051312360837000_40.1.11.13","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmg017"},{"key":"2024051312360837000_40.1.11.14","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/jbmr.5650070303","volume":"7","year":"1992","journal-title":"J Bone Miner Res"},{"key":"2024051312360837000_40.1.11.15","unstructured":"Phillips B, Ball C, Sackett D, et al. 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