{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:03:19Z","timestamp":1791237799147,"version":"4.1.0"},"reference-count":20,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Sports Med"],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>In this study, the impact of regular training on left ventricle morphology in a group of athletes with bicuspid aortic valve (BAV) was evaluated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>Longitudinal cohort study. A group of competitive athletes with BAV was followed up with a yearly standard echocardiographic examination for 5 years.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Setting<\/jats:title>\n                  <jats:p>Sport Medicine Centre, University of Florence, Pre-Participation Protocol Study<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Participants<\/jats:title>\n                  <jats:p>A group of 88 consecutive athletes diagnosed with BAV was identified in the period January to December 1999, and 30 of these completed a 5-year follow-up. They were compared with a group of 56 athletes with a normal tricuspid valve (TAV).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>BAV athletes showed significant progressive increase in left ventricular dimensions and aortic diameters at four levels. The values were within the range of the general and non-athletic BAV populations. In TAV athletes, the aortic and left ventricle dimensions did not increase significantly and remained within physiological range.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Left ventricular dimensions in competitive BAV athletes remain within the normal range. There is, however, a significant progressive increase in the BAV group compared with the TAV group. These results are in agreement with data obtained in previous studies on the non-athletic BAV population. Sports activity does not have an additional effect on cardiac morphology in athletes with asymptomatic BAV associated with mild regurgitation, for at least 5 years.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bjsm.2008.047407","type":"journal-article","created":{"date-parts":[[2008,6,3]],"date-time":"2008-06-03T22:58:20Z","timestamp":1212533900000},"page":"275-279","source":"Crossref","is-referenced-by-count":44,"title":["Effects of sports activity in athletes with bicuspid aortic valve and mild aortic regurgitation"],"prefix":"10.1136","volume":"44","author":[{"given":"G","family":"Galanti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Stefani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Toncelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M C R","family":"Vono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Mercuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Maffulli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2008,6,3]]},"reference":[{"key":"2025080113275187000_44.4.275.1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000027905.26586.E8"},{"key":"2025080113275187000_44.4.275.2","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2006.033530"},{"key":"2025080113275187000_44.4.275.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2003.11.031"},{"key":"2025080113275187000_44.4.275.4","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(70)90761-7"},{"key":"2025080113275187000_44.4.275.5","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.1.35"},{"key":"2025080113275187000_44.4.275.6","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1136\/hrt.82.1.19","article-title":"Aortic root dilatation in young men with normally functioning bicuspid aortic valves","volume":"82","author":"Nistri","year":"1999","journal-title":"Heart"},{"key":"2025080113275187000_44.4.275.7","doi-asserted-by":"publisher","DOI":"10.1136\/heart.83.1.81"},{"key":"2025080113275187000_44.4.275.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.02.010"},{"key":"2025080113275187000_44.4.275.9","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(10)80188-3"},{"key":"2025080113275187000_44.4.275.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(03)00462-4"},{"key":"2025080113275187000_44.4.275.11","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/j.echo.2003.08.001","article-title":"ACC\/AHA\/ASE 2003 Guideline update for the clinical application of echocardiography: a report of the American College of Cardiology, American Heart Association Task Force on Practice Guidelines","volume":"10","author":"Cheitilin","year":"2003","journal-title":"J Am Soc Echocardiogr"},{"key":"2025080113275187000_44.4.275.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.02.056"},{"key":"2025080113275187000_44.4.275.13","first-page":"1251","article-title":"Detection of left ventricular hypertrophy by M-mode echocardiography. Anatomic validation, standardization and comparison to other methods","volume":"20","author":"Devereux","year":"1987","journal-title":"Hypertension"},{"key":"2025080113275187000_44.4.275.14","first-page":"507","article-title":"Two-dimensional echocardiographic aortic root dimensions in normal children and adults","volume":"64","author":"Roman","year":"1","journal-title":"Am J Cardiol 1989 Sep"},{"key":"2025080113275187000_44.4.275.15","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.3.278"},{"key":"2025080113275187000_44.4.275.16","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.16.2138"},{"key":"2025080113275187000_44.4.275.17","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.88.1.37"},{"key":"2025080113275187000_44.4.275.18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.7.3819"},{"key":"2025080113275187000_44.4.275.19","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1161\/01.cir.0000087449.03964.fb","article-title":"Failure to prevent progressive dilatation of ascendig aorta by aortic valve replacement in patients with bicuspid aortic valve: comparison with tricuspid aortic valve","volume":"108","author":"Yasuda","year":"2003","journal-title":"Circulation"},{"key":"2025080113275187000_44.4.275.20","unstructured":"Feigenbaum H Armstrong FW Ryan T . 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