{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T17:17:11Z","timestamp":1791652631982,"version":"4.3.4"},"reference-count":30,"publisher":"BMJ","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br J Sports Med"],"accepted":{"date-parts":[[2010,6,1]]},"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>There is increasing evidence to suggest many elite athletes fail to recognise and report symptoms of exercise-induced bronchoconstriction (EIB), supporting the contention that athletes should be screened routinely for EIB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To screen elite British athletes for EIB using eucapnic voluntary hyperpnoea (EVH).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>228 elite athletes provided written informed consent and completed an EVH challenge with maximal flow volume loops measured at baseline and 3, 5, 10 and 15 min following EVH. A fall of 10% in forced expiratory volume in 1 s (FEV<jats:sub>1<\/jats:sub>) from baseline was deemed positive. Two-way analysis of variance was conducted to compare FEV<jats:sub>1<\/jats:sub>at baseline and maximal change following EVH between EVH-positive and EVH-negative athletes who did and did not report a previous diagnosis of EIB. Significance was assumed if p\u22640.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Following the EVH challenge 78 athletes (34%) demonstrated EVH positive. 57 out of the 78 (73%) athletes who demonstrated EVH positive did not have a previous diagnosis of EIB. 30 athletes reported a previous diagnosis of asthma, nine (30%) of whom demonstrated EVH negative. There was no significant difference between the magnitude of the fall in FEV<jats:sub>1<\/jats:sub>between athletes who reported a previous diagnosis of EIB and demonstrated EVH positive, and those with no previous diagnosis of EIB who demonstrated EVH positive (mean\u00b1SD; \u221221.6\u00b116.1% vs \u221217.1\u00b19.7%; p=0.07).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The high proportion of previously undiagnosed athletes who demonstrated EVH positive suggests that elite athletes should be screened routinely for EIB using a suitable bronchoprovocation challenge.<\/jats:p><\/jats:sec>","DOI":"10.1136\/bjsm.2010.072520","type":"journal-article","created":{"date-parts":[[2010,7,21]],"date-time":"2010-07-21T01:10:17Z","timestamp":1279674617000},"page":"1126-1131","source":"Crossref","is-referenced-by-count":53,"title":["Diagnosis of exercise-induced bronchoconstriction: eucapnic voluntary hyperpnoea challenges identify previously undiagnosed elite athletes with exercise-induced bronchoconstriction"],"prefix":"10.1136","volume":"45","author":[{"given":"John","family":"Dickinson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"McConnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg","family":"Whyte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2010,7,20]]},"reference":[{"key":"2024051314051502000_45.14.1126.1","unstructured":"Anderson S . 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