{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T03:26:57Z","timestamp":1789615617525,"version":"build-2803163510"},"reference-count":65,"publisher":"BMJ","issue":"9","license":[{"start":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T00:00:00Z","timestamp":1581552000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Queensland Orthopaedic Physiotherapy Network"},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["U54-GM104941"],"award-info":[{"award-number":["U54-GM104941"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001782","name":"University of Melbourne","doi-asserted-by":"publisher","award":["Research Collaboration Grant"],"award-info":[{"award-number":["Research Collaboration Grant"]}],"id":[{"id":"10.13039\/501100001782","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1114296"],"award-info":[{"award-number":["1114296"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1121173"],"award-info":[{"award-number":["1121173"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001215","name":"La Trobe University","doi-asserted-by":"publisher","award":["Sport, Exercise and Rehabilitation Focus Area (102"],"award-info":[{"award-number":["Sport, Exercise and Rehabilitation Focus Area (102"]}],"id":[{"id":"10.13039\/501100001215","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005247","name":"University of British Columbia","doi-asserted-by":"publisher","award":["Society for Mobility and Health"],"award-info":[{"award-number":["Society for Mobility and Health"]}],"id":[{"id":"10.13039\/501100005247","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000940","name":"Arthritis Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000940","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Sports Med"],"accepted":{"date-parts":[[2020,1,17]]},"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Not meeting functional performance criteria increases reinjury risk after ACL reconstruction (ACLR), but the implications for osteoarthritis are not well known.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine if poor functional performance post-ACLR is associated with risk of worsening early osteoarthritis features, knee symptoms, function and quality of life (QoL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seventy-eight participants (48 men) aged 28\u00b115 years completed a functional performance test battery (three hop tests, one-leg-rise) 1 year post-ACLR. Poor functional performance was defined as &lt;90%\u2009limb symmetry index (LSI) on each test. At 1 and 5\u2009years, MRI, Knee injury Osteoarthritis Outcome Score (KOOS) and International Knee Documentation Committee (IKDC) subjective form were completed. Primary outcomes were: (i) worsening patellofemoral and tibiofemoral MRI-osteoarthritis features (cartilage, bone marrow lesions (BMLs) and meniscus) and (ii) change in KOOS and IKDC scores, between 1 and 5\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Only 14 (18%) passed (\u226590% LSI on all tests) the functional test battery. Poor functional performance on the battery (all four tests &lt;90% LSI) 1 year post-ACLR was associated with 3.66 times (95%\u2009CI 1.12 to 12.01) greater risk of worsening patellofemoral BMLs. A triple-crossover hop &lt;90% LSI was associated with 2.09 (95% CI 1.15 to 3.81) times greater risk of worsening patellofemoral cartilage. There was generally no association between functional performance and tibiofemoral MRI-osteoarthritis features, or KOOS\/IKDC scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Only one in five participants met common functional performance criteria (\u226590% LSI all four tests) 1 year post-ACLR. Poor function on all four tests was associated with a 3.66 times increased risk of worsening patellofemoral BMLs, and generally not associated with decline in self-reported outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1136\/bjsports-2019-101503","type":"journal-article","created":{"date-parts":[[2020,4,10]],"date-time":"2020-04-10T21:15:25Z","timestamp":1586553325000},"page":"546-555","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":51,"title":["Poor functional performance 1 year after ACL reconstruction increases the risk of early osteoarthritis progression"],"prefix":"10.1136","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6570-5429","authenticated-orcid":false,"given":"Brooke","family":"Patterson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9491-0264","authenticated-orcid":false,"given":"Adam Geoffrey","family":"Culvenor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3545-5094","authenticated-orcid":false,"given":"Christian J","family":"Barton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9374-8266","authenticated-orcid":false,"given":"Ali","family":"Guermazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Stefanik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayden G","family":"Morris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy S","family":"Whitehead","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5892-129X","authenticated-orcid":false,"given":"Kay M","family":"Crossley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,4,10]]},"reference":[{"key":"2024101110151244000_54.9.546.1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20589"},{"key":"2024101110151244000_54.9.546.2","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2018-100022"},{"key":"2024101110151244000_54.9.546.3","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2018-099751"},{"key":"2024101110151244000_54.9.546.4","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1002\/acr.20299","article-title":"Quadriceps muscle weakness after anterior cruciate ligament reconstruction: a risk factor for knee osteoarthritis?","volume":"62","author":"\u00d8Iestad","year":"2010","journal-title":"Arthritis Care Res"},{"key":"2024101110151244000_54.9.546.5","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1002\/art.39005","article-title":"Early knee osteoarthritis is evident one year following anterior cruciate ligament reconstruction: a magnetic resonance imaging evaluation","volume":"67","author":"Culvenor","year":"2015","journal-title":"Arthritis Rheumatol"},{"key":"2024101110151244000_54.9.546.6","doi-asserted-by":"publisher","DOI":"10.1177\/0363546516631936"},{"key":"2024101110151244000_54.9.546.7","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1177\/0363546518789685","article-title":"Worsening knee osteoarthritis features on magnetic resonance imaging 1 to 5 years after anterior cruciate ligament reconstruction","volume":"46","author":"Patterson","year":"2018","journal-title":"Am J Sports Med"},{"key":"2024101110151244000_54.9.546.8","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-208129"},{"key":"2024101110151244000_54.9.546.9","doi-asserted-by":"crossref","first-page":"232596711351830","DOI":"10.1177\/2325967113518305","article-title":"Functional performance testing after anterior cruciate ligament reconstruction","volume":"2","author":"Abrams","year":"2014","journal-title":"Orthop J Sports Med"},{"key":"2024101110151244000_54.9.546.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2014.10.008"},{"key":"2024101110151244000_54.9.546.11","doi-asserted-by":"publisher","DOI":"10.1177\/0363546515578252"},{"key":"2024101110151244000_54.9.546.12","doi-asserted-by":"publisher","DOI":"10.1177\/0363546514552184"},{"key":"2024101110151244000_54.9.546.13","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nrrheum.2015.135","article-title":"Strategies for the prevention of knee osteoarthritis","volume":"12","author":"Roos","year":"2016","journal-title":"Nat Rev Rheumatol"},{"key":"2024101110151244000_54.9.546.14","doi-asserted-by":"crossref","unstructured":"Hart HF , Culvenor AG , Guermazi A , et al . 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