{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T13:22:00Z","timestamp":1794057720383,"version":"4.8.0"},"reference-count":63,"publisher":"BMJ","issue":"20","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Sports Med"],"accepted":{"date-parts":[[2023,6,16]]},"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To perform a large-scale pairwise and network meta-analysis on the effects of all relevant exercise training modes on resting blood pressure to establish optimal antihypertensive exercise prescription practices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Systematic review and network meta-analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data sources<\/jats:title>\n                    <jats:p>PubMed (Medline), the Cochrane library and Web of Science were systematically searched.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Eligibility criteria<\/jats:title>\n                    <jats:p>Randomised controlled trials published between 1990 and February 2023. All relevant work reporting reductions in systolic blood pressure (SBP) and\/or diastolic blood pressure (DBP) following an exercise intervention of \u22652 weeks, with an eligible non-intervention control group, were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>270 randomised controlled trials were ultimately included in the final analysis, with a pooled sample size of 15\u2009827 participants. Pairwise analyses demonstrated significant reductions in resting SBP and DBP following aerobic exercise training (\u22124.49\/\u20132.53\u2009mm Hg, p&lt;0.001), dynamic resistance training (\u20134.55\/\u20133.04\u2009mm Hg, p&lt;0.001), combined training (\u20136.04\/\u20132.54\u2009mm Hg, p&lt;0.001), high-intensity interval training (\u20134.08\/\u20132.50\u2009mm Hg, p&lt;0.001) and isometric exercise training (\u20138.24\/\u20134.00\u2009mm Hg, p&lt;0.001). As shown in the network meta-analysis, the rank order of effectiveness based on the surface under the cumulative ranking curve (SUCRA) values for SBP were isometric exercise training (SUCRA: 98.3%), combined training (75.7%), dynamic resistance training (46.1%), aerobic exercise training (40.5%) and high-intensity interval training (39.4%). Secondary network meta-analyses revealed isometric wall squat and running as the most effective submodes for reducing SBP (90.4%) and DBP (91.3%), respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Various exercise training modes improve resting blood pressure, particularly isometric exercise. The results of this analysis should inform future exercise guideline recommendations for the prevention and treatment of arterial hypertension.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bjsports-2022-106503","type":"journal-article","created":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T20:15:18Z","timestamp":1690316118000},"page":"1317-1326","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":283,"title":["Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials"],"prefix":"10.1136","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7963-2550","authenticated-orcid":false,"given":"Jamie J","family":"Edwards","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Algis H 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