{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:38:55Z","timestamp":1792132735908,"version":"4.4.0"},"reference-count":70,"publisher":"BMJ","issue":"17","funder":[{"DOI":"10.13039\/100016799","name":"Natural Science Foundation of Guangzhou Municipality","doi-asserted-by":"publisher","award":["2024A04J6477"],"award-info":[{"award-number":["2024A04J6477"]}],"id":[{"id":"10.13039\/100016799","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["Sun Yat-sen University, 2025QNPY01"],"award-info":[{"award-number":["Sun Yat-sen University, 2025QNPY01"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Br J Sports Med"],"accepted":{"date-parts":[[2026,7,1]]},"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the effects of supervised exercise on gestational diabetes mellitus (GDM) and other pregnancy outcomes and examine dose\u2013response relationships.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Systematic review with random-effects meta-analysis and meta-regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data sources<\/jats:title>\n                    <jats:p>Four databases were searched up to November 2025.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Eligibility criteria<\/jats:title>\n                    <jats:p>Randomised controlled trials in pregnant women comparing supervised exercise with usual care were included if they reported GDM. GDM was prespecified as the primary outcome, while other outcomes were extracted where available, including gestational hypertension (GH), pre-eclampsia, excessive gestational weight gain (EGWG), macrosomia, caesarean delivery, preterm birth and low birth weight.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nineteen studies (n=6213; 48.6% in intervention groups) were included, with moderate certainty of evidence. Supervised exercise reduced the risk of GDM (risk ratio (RR) 0.74, 95% CI 0.57 to 0.96; I\n                      <jats:sup>2<\/jats:sup>\n                      =47%), GH (RR 0.55, 95%\u2009CI 0.40 to 0.77; I\n                      <jats:sup>2<\/jats:sup>\n                      =1%), EGWG (RR 0.75, 95%\u2009CI 0.61 to 0.92; I\n                      <jats:sup>2<\/jats:sup>\n                      =70%) and macrosomia (RR 0.61, 95%\u2009CI 0.46 to 0.81; I\n                      <jats:sup>2<\/jats:sup>\n                      =27%). Subgroup analyses for these outcomes suggested greater effects with earlier intervention (initiated in early pregnancy or duration &gt;20 weeks), higher adherence (\u226580%), combined aerobic and resistance training, and weekly exercise duration \u2265150\u2009min\/week. Significant subgroup differences in GDM risk were observed for intervention initiation timing (p=0.009) and intervention duration (p=0.010). Dose\u2013response analysis showed a peak effect at approximately 500\u2013550\u2009metabolic equivalent task-minutes per week for EGWG, with a plateau at higher doses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Supervised exercise during pregnancy reduces adverse pregnancy outcomes when initiated early, with high adherence, at moderate doses, and with combined aerobic and resistance training.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bjsports-2026-111586","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T17:25:12Z","timestamp":1784136312000},"page":"1350-1358","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of supervised exercise during pregnancy on gestational diabetes mellitus and other pregnancy outcomes: a systematic review and meta-analysis"],"prefix":"10.1136","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1267-710X","authenticated-orcid":false,"given":"Lingxia","family":"Li","sequence":"first","affiliation":[{"name":"Department of Nutrition, Sun Yat-Sen University School of Public Health, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0599-9695","authenticated-orcid":false,"given":"Jialin","family":"He","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Sun Yat-Sen University School of Public Health, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4988-7195","authenticated-orcid":false,"given":"Chun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Sun Yat-Sen University School of Public Health, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9728-5363","authenticated-orcid":false,"given":"Ludi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Statistics and Epidemiology, Sun Yat-Sen University School of Public Health, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2049-391X","authenticated-orcid":false,"given":"Bingqi","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Statistics and Epidemiology, Sun Yat-Sen University School of Public Health, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-0692-8531","authenticated-orcid":false,"given":"Shanshan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Sun Yat-Sen University School of Public Health, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5533-8434","authenticated-orcid":false,"given":"Jiarui","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Sun Yat-Sen University School of Public Health, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0646-0094","authenticated-orcid":false,"given":"Qian","family":"Chen","sequence":"additional","affiliation":[{"name":"Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Department of Cardiology, Sun Yat-Sen Memorial Hospital, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6358-4056","authenticated-orcid":false,"given":"Yan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Sun Yat-Sen University School of Public Health, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5330-6466","authenticated-orcid":false,"given":"Min","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Sun Yat-Sen University School of Public Health, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,7,15]]},"reference":[{"key":"2026092200300752000_60.17.1350.1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.0593"},{"key":"2026092200300752000_60.17.1350.2","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S2213-8587(25)00063-4","article-title":"Continuous glucose monitoring in the management of gestational diabetes in Switzerland (DipGluMo): an open-label, single-centre, randomised, controlled trial","volume":"13","author":"Amylidi-Mohr","year":"2025","journal-title":"Lancet Diabetes Endocrinol"},{"key":"2026092200300752000_60.17.1350.3","unstructured":"World Health Organization . 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