{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T18:18:48Z","timestamp":1771006728494,"version":"3.50.1"},"reference-count":0,"publisher":"BMJ","issue":"5856","license":[{"start":{"date-parts":[[1973,3,31]],"date-time":"1973-03-31T00:00:00Z","timestamp":102384000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J"],"published-print":{"date-parts":[[1973,3,31]]},"abstract":"<jats:p>A descriptive epidemiological study of simple hypospadias\u2014that is, hypospadias without coexisting malformation outside the genital system\u2014in a birth population of 46,927 singleton males and 1,013 twin males showed that the condition was significantly more common (P &lt; 0\u00b7001) in uniovular twin males than in either singleton or binovular twin males. Also the temporal distribution of dates of conception had a significant cyclic pattern for each year of the study. Both observations are thought to support the view that gonadotrophin levels at stage 3 sexual organogenesis play an important part in normal masculinization of male external genitalia.<\/jats:p>","DOI":"10.1136\/bmj.1.5856.768","type":"journal-article","created":{"date-parts":[[2009,4,8]],"date-time":"2009-04-08T15:21:07Z","timestamp":1239204067000},"page":"768-770","source":"Crossref","is-referenced-by-count":64,"title":["Observations on the Epidemiology of Simple Hypospadias"],"prefix":"10.1136","volume":"1","author":[{"given":"C. J.","family":"Roberts","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Lloyd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1973,3,31]]},"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.1.5856.768","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.1.5856.768","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,16]],"date-time":"2025-11-16T23:12:48Z","timestamp":1763334768000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.1.5856.768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,3,31]]},"references-count":0,"journal-issue":{"issue":"5856","published-online":{"date-parts":[[1973,3,31]]},"published-print":{"date-parts":[[1973,3,31]]}},"alternative-id":["10.1136\/bmj.1.5856.768"],"URL":"https:\/\/doi.org\/10.1136\/bmj.1.5856.768","relation":{},"ISSN":["0007-1447","1468-5833"],"issn-type":[{"value":"0007-1447","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,3,31]]}}}