{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T17:57:10Z","timestamp":1764957430302,"version":"3.46.0"},"reference-count":0,"publisher":"BMJ","issue":"5707","license":[{"start":{"date-parts":[[1970,5,23]],"date-time":"1970-05-23T00:00:00Z","timestamp":12268800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J"],"published-print":{"date-parts":[[1970,5,23]]},"abstract":"<jats:p>\n                    Seven patients in acute exacerbation of chronic respiratory failure were given 24\u00b75% and later 28% oxygen through Ventimasks. The mean increases in arterial PO\n                    <jats:sub>2<\/jats:sub>\n                    were 11 and 21 mm. Hg while breathing 24\u00b75% and 28% oxygen respectively compared with control values while breathing air. Associated increases in arterial PCO\n                    <jats:sub>2<\/jats:sub>\n                    were 4 and 8 mm. Hg, respectively. In five of the patients these increases in inspired oxygen concentration resulted in useful increases in tissue oxygen supply without significant deterioration in ventilation, but in two patients arterial PCO\n                    <jats:sub>2<\/jats:sub>\n                    rose excessively and artificial ventilation was required.\n                  <\/jats:p>","DOI":"10.1136\/bmj.2.5707.452","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T07:02:10Z","timestamp":1238655730000},"page":"452-455","source":"Crossref","is-referenced-by-count":23,"title":["Effect of Controlled Oxygen Therapy on Arterial Blood Gases in Acute Respiratory Failure"],"prefix":"10.1136","volume":"2","author":[{"given":"D. A.","family":"Warrell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. H. T.","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Godfrey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. L.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1970,5,23]]},"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.2.5707.452","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.2.5707.452","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T17:53:02Z","timestamp":1764957182000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.2.5707.452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,5,23]]},"references-count":0,"journal-issue":{"issue":"5707","published-online":{"date-parts":[[1970,5,23]]},"published-print":{"date-parts":[[1970,5,23]]}},"alternative-id":["10.1136\/bmj.2.5707.452"],"URL":"https:\/\/doi.org\/10.1136\/bmj.2.5707.452","relation":{},"ISSN":["0007-1447","1468-5833"],"issn-type":[{"type":"print","value":"0007-1447"},{"type":"electronic","value":"1468-5833"}],"subject":[],"published":{"date-parts":[[1970,5,23]]}}}