{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T18:10:44Z","timestamp":1788977444900,"version":"build-2803163510"},"reference-count":0,"publisher":"BMJ","issue":"6091","license":[{"start":{"date-parts":[[1977,10,1]],"date-time":"1977-10-01T00:00:00Z","timestamp":244512000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J"],"published-print":{"date-parts":[[1977,10,1]]},"abstract":"<jats:p>Serial 25-hydroxy vitamin D (25-OHD) concentrations were measured in long-stay geriatric patients treated with vitamin D. Comparison between a treatment and a control group showed that a daily dose of 500 IU vitamin D produced a significant increase in 25-OHD levels by two months. The supplement had a striking effect when the initial 25-OHD level was low and very little effect when it was high. 25-OHD levels in subjects on 2000 IU vitamin D daily were only marginally higher than those in subjects on 500 IU. A dose of 500 IU vitamin D daily should therefore produce adequate blood 25-OHD concentrations in most old people, and probably prevent most cases of osteomalacia in the elderly--though a large-scale study is needed to confirm this.<\/jats:p>","DOI":"10.1136\/bmj.2.6091.859","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T18:32:30Z","timestamp":1238697150000},"page":"859-861","source":"Crossref","is-referenced-by-count":45,"title":["Vitamin D supplements and 25-hydroxy vitamin D concentrations in the elderly."],"prefix":"10.1136","volume":"2","author":[{"given":"W J","family":"MacLennan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J C","family":"Hamilton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1977,10,1]]},"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.2.6091.859","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.2.6091.859","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T18:52:08Z","timestamp":1765047128000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.2.6091.859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,10,1]]},"references-count":0,"journal-issue":{"issue":"6091","published-online":{"date-parts":[[1977,10,1]]},"published-print":{"date-parts":[[1977,10,1]]}},"alternative-id":["10.1136\/bmj.2.6091.859"],"URL":"https:\/\/doi.org\/10.1136\/bmj.2.6091.859","relation":{},"ISSN":["0007-1447","1468-5833"],"issn-type":[{"value":"0007-1447","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,10,1]]}}}