{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T17:49:19Z","timestamp":1773078559788,"version":"3.50.1"},"reference-count":0,"publisher":"BMJ","issue":"6200","license":[{"start":{"date-parts":[[1979,11,17]],"date-time":"1979-11-17T00:00:00Z","timestamp":311644800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J"],"published-print":{"date-parts":[[1979,11,17]]},"abstract":"<jats:p>To determine the pathogenesis of neonatal hyperbilirubinaemia after oxytocin-induced labour venous cord blood from 95 healthy newborn infants was examined. Of these, 15 were delivered by elective caesarean section, 40 after spontaneous labour, and 40 after oxytocin-induced labour. There was no significant difference in any haematological or biochemical variable between the first two groups. Infants born after oxytocin-induced labour, however, showed clear evidence of increased haemolysis associated with significantly decreased erythrocyte deformability (P less than 0.001). In-vitro studies showed a time- and dose-related reduction in erythrocyte deformability in response to oxytocin. The findings suggest that the vasopressin-like action of oxytocin causes osmotic swelling of erythrocytes leading to decreased deformability and hence more rapid destruction with resultant hyperbilirubinaemia in the neonate.<\/jats:p>","DOI":"10.1136\/bmj.2.6200.1255","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T18:32:30Z","timestamp":1238697150000},"page":"1255-1257","source":"Crossref","is-referenced-by-count":42,"title":["Pathogenesis of neonatal hyperbilirubinaemia after induction of labour with oxytocin."],"prefix":"10.1136","volume":"2","author":[{"given":"P C","family":"Buchan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1979,11,17]]},"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.2.6200.1255","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.2.6200.1255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T14:51:24Z","timestamp":1765464684000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.2.6200.1255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,11,17]]},"references-count":0,"journal-issue":{"issue":"6200","published-online":{"date-parts":[[1979,11,17]]},"published-print":{"date-parts":[[1979,11,17]]}},"alternative-id":["10.1136\/bmj.2.6200.1255"],"URL":"https:\/\/doi.org\/10.1136\/bmj.2.6200.1255","relation":{},"ISSN":["0007-1447","1468-5833"],"issn-type":[{"value":"0007-1447","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,11,17]]}}}