{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T02:41:13Z","timestamp":1774579273692,"version":"3.50.1"},"reference-count":13,"publisher":"BMJ","issue":"6234","license":[{"start":{"date-parts":[[1980,7,19]],"date-time":"1980-07-19T00:00:00Z","timestamp":332812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J"],"published-print":{"date-parts":[[1980,7,19]]},"abstract":"<jats:p>In an attempt to clarify the nature of the \"menopausal syndrome\" a survey of symptoms was carried out by means of postal questionnaires in a population sample of 1120 women and 510 men. Special care was taken to avoid letting the participants know that the survey was mainly concerned with the menopause. Response rates were 72% for women and 68% for men. Analysis of patterns of symptoms by age and sex showed that peaks of prevalence of flushing and sweating were closely associated with the mean age of menopause, coinciding with it or occurring a little after it. Less impressive peaks of prevalence of a group of minor mental symptoms were associated with an age just preceding the mean age of menopause. Complaints about aching breasts, irritability, and low backache diminished after the menopause. No association with the menopause was found for various other symptoms. The results of this study support the view that the menopausal syndrome exists but do not, of course, provide any evidence concerning the effectiveness (or safety) of hormone treatment.<\/jats:p>","DOI":"10.1136\/bmj.281.6234.181","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T18:32:30Z","timestamp":1238697150000},"page":"181-183","source":"Crossref","is-referenced-by-count":190,"title":["Study of symptoms in middle life with special reference to the menopause."],"prefix":"10.1136","volume":"281","author":[{"given":"G T","family":"Bungay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M P","family":"Vessey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C K","family":"McPherson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1980,7,19]]},"reference":[{"key":"ref_1","article-title":"A study of symptoms in middle life with special reference to the menopause","author":"Bungay, G.T.","year":"1979","unstructured":"Bungay GT. A study of symptoms in middle life with special reference to the menopause. MFCM thesis. 1979.","journal-title":"MFCM thesis"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/00006842-196505000-00009","article-title":"Menopausal symptoms in women of various ages","volume":"27","author":"Neugarten, B.L.; Kraines, R.J.","year":"1965","unstructured":"Neugarten BL, Kraines RJ. Menopausal symptoms in women of various ages. Psychosom Med 1965;27:266-73.","journal-title":"Psychosom Med"},{"key":"ref_3","first-page":"1325","article-title":"Die Beziehung von erkrankungen und socialpsychologischen Fakten zum Klimacterium","volume":"61","author":"Prill, H.J.","year":"1966","unstructured":"Prill HJ. Die Beziehung von erkrankungen und socialpsychologischen Fakten zum Klimacterium. Med Klin 1966;61:1325-8.","journal-title":"Med Klin"},{"key":"ref_4","first-page":"268","volume":"4","author":"Gynaecology, Medical; Sociology","year":"1969","unstructured":"Medical Gynaecology and Sociology 1969;4:268-77."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1017\/S0021932000008956","article-title":"Menopausal age and symptomatology in a general practice","volume":"5","author":"Thompson, B.; Hart, S.A.; Durno, D.","year":"1973","unstructured":"Thompson B, Hart SA, Durno D. Menopausal age and symptomatology in a general practice. Y Biosoc Sci 1973;5:71-82.","journal-title":"Y Biosoc Sci"},{"key":"ref_6","first-page":"108","article-title":"The menopausal syndrome","volume":"28","author":"McKinlay, S.M.; Jefferys, M.","year":"1974","unstructured":"McKinlay SM, Jefferys M. The menopausal syndrome. Br J Prev Soc Med 1974;28:108-15.","journal-title":"Br J Prev Soc Med"},{"key":"ref_7","first-page":"496","article-title":"Menopausal myths. MedJ7 Aust","volume":"i:","author":"Wood, C.","year":"1979","unstructured":"Wood C. Menopausal myths. MedJ7 Aust 1979;i:496-9."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1136\/bmj.3.5979.344","article-title":"Psychiatric morbidity and the menopause: screening of general population sample","volume":"iii:","author":"Ballinger, C.B.","year":"1975","unstructured":"Ballinger CB. Psychiatric morbidity and the menopause: screening of general population sample. Br MedJr 1975;iii:344-6.","journal-title":"Br MedJr"},{"key":"ref_9","first-page":"241","article-title":"Medical information systems in general practice: a","volume-title":"community health project. Proc R Soc Med","volume":"65","author":"Perry, J.","year":"1972","unstructured":"Perry J. Medical information systems in general practice: a community health project. Proc R Soc Med 1972;65:241-2."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1159\/000401988","article-title":"Uterine cancer and estrogen therapy","volume":"5","author":"Mack, T.M.","year":"1978","unstructured":"Mack TM. Uterine cancer and estrogen therapy. Front Horm Res 1978;5: 101-16.","journal-title":"Front Horm Res"},{"key":"ref_11","first-page":"1575","article-title":"Relations between bleeding pattern, endometrial histology and oestrogen treatment in menopausal women","volume":"i:","author":"Sturdee, D.W.; Wade-Evans, T.; Paterson, M.E.L.; Thom, M.; Studd, J.W.W.","year":"1978","unstructured":"Sturdee DW, Wade-Evans T, Paterson MEL, Thom M, Studd JWW. Relations between bleeding pattern, endometrial histology and oestrogen treatment in menopausal women. Br MedJ 1978;i:1575-7.","journal-title":"Br MedJ"},{"key":"ref_12","article-title":"Accepted","year":"1980","unstructured":"(Accepted 14 May 1980)"},{"key":"ref_13","article-title":"The sample of patients on general practitioners' lists was satisfactory and adequately representative of the general population. A reasonable reply rate was obtained, even though we used two questionnaires to avoid bias in response to the symptom questions. The survey of symptoms in both sexes over a wide age range enabled us to examine the pattern of complaints in the women in a way that complements and extends previous epidemiological studies. The finding of a clear association with the menopause for vasomotor symptoms concurs with the results of other studies.4-6 The results for psychiatric symptoms, with peaks of prevalence occurring just before the mean age of menopause, agree well with the conclusions of Jaszmann et a14 and Ballinger.8 The study provides no support for an association between the menopause and muscle and joint aches3 4 or","unstructured":"The sample of patients on general practitioners' lists was satisfactory and adequately representative of the general population. A reasonable reply rate was obtained, even though we used two questionnaires to avoid bias in response to the symptom questions. The survey of symptoms in both sexes over a wide age range enabled us to examine the pattern of complaints in the women in a way that complements and extends previous epidemiological studies. The finding of a clear association with the menopause for vasomotor symptoms concurs with the results of other studies.4-6 The results for psychiatric symptoms, with peaks of prevalence occurring just before the mean age of menopause, agree well with the conclusions of Jaszmann et a14 and Ballinger.8 The study provides no support for an association between the menopause and muscle and joint aches3 4 or"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.281.6234.181","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.281.6234.181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T21:09:22Z","timestamp":1765400962000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.281.6234.181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,7,19]]},"references-count":13,"journal-issue":{"issue":"6234","published-online":{"date-parts":[[1980,7,19]]},"published-print":{"date-parts":[[1980,7,19]]}},"alternative-id":["10.1136\/bmj.281.6234.181"],"URL":"https:\/\/doi.org\/10.1136\/bmj.281.6234.181","relation":{},"ISSN":["0007-1447","1468-5833"],"issn-type":[{"value":"0007-1447","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,7,19]]}}}