{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:18:02Z","timestamp":1756995482941},"reference-count":33,"publisher":"BMJ","issue":"6269","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ"],"published-print":{"date-parts":[[1981,3,28]]},"DOI":"10.1136\/bmj.282.6269.1020","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T15:00:59Z","timestamp":1238684459000},"page":"1020-1022","source":"Crossref","is-referenced-by-count":39,"title":["Diagnosis of deep vein thrombosis using autologous indium-III-labelled platelets."],"prefix":"10.1136","volume":"282","author":[{"given":"A","family":"Fenech","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J K","family":"Hussey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F W","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P P","family":"Dendy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A S","family":"Douglas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"438","article-title":"Can colonic bacterial metabolites predispose to cholesterol gallstones ? Br MedJ7","volume":"i:","author":"Low-Beer, T.S.; Pomare, E.W.","year":"1975","unstructured":"Low-Beer TS, Pomare EW. Can colonic bacterial metabolites predispose to cholesterol gallstones ? Br MedJ7 1975;i:438-40."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/S0016-5085(77)80317-X","article-title":"Effect of deoxycholic acid ingestion on bile acid metabolism and biliary lipid secretion in normal subjects","volume":"72","author":"LaRusso, N.F.; Szczepanik, P.A.; Hofmann, A.F.","year":"1977","unstructured":"LaRusso NF, Szczepanik PA, Hofmann AF. Effect of deoxycholic acid ingestion on bile acid metabolism and biliary lipid secretion in normal subjects. Gastroenterology 1977;72:132-40.","journal-title":"Gastroenterology"},{"key":"ref_3","first-page":"249","article-title":"Influence of deoxycholic acid on biliary lipids in man","volume":"53","author":"Ahlberg, J.; Angelin, B.; Einarrson, K.; Hellstrom, K.; Leijd, B.","year":"1977","unstructured":"Ahlberg J, Angelin B, Einarrson K, Hellstrom K, Leijd B. Influence of deoxycholic acid on biliary lipids in man. Clinical Science and Molecular Medicine 1977;53:249-56.","journal-title":"Clinical Science and Molecular Medicine"},{"key":"ref_4","first-page":"637","article-title":"Bile acid feeding and hepatic sterol metabolism: effect","volume-title":"of deoxycholic acid. Gastroenterology 1980; 79","author":"Carulli, N.; Ponz de Leon, M.; Zirori, F.; Iori, R.; Loria, P.","unstructured":"Carulli N, Ponz de Leon M, Zirori F, Iori R, Loria P. Bile acid feeding and hepatic sterol metabolism: effect of deoxycholic acid. Gastroenterology 1980;79:637-41."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/S0140-6736(78)91800-7","article-title":"Colonic bacterial activity, biliary cholesterol saturation and pathogenesis of gallstones","volume":"ii:","author":"Low-Beer, T.S.; Nutter, S.","year":"1978","unstructured":"Low-Beer TS, Nutter S. Colonic bacterial activity, biliary cholesterol saturation and pathogenesis of gallstones. Lancet 1978;ii:1063-5.","journal-title":"Lancet"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1699-0463.1968.tb01345.x","article-title":"Parameters in 7cr-dehydroxylation of bile acids by anaerobic lactobacilli","volume":"72","author":"Midtvedt, T.; Norman, A.","year":"1968","unstructured":"Midtvedt T, Norman A. Parameters in 7cr-dehydroxylation of bile acids by anaerobic lactobacilli. Acta Pathol Microbiol Scand 1968;72:313-29.","journal-title":"Acta Pathol Microbiol Scand"},{"key":"ref_7","first-page":"535","article-title":"Degradation of steroids by intestinal bacteria II","volume":"202","author":"Aries, V.; Hill, M.J.","year":"1970","unstructured":"Aries V, Hill MJ. Degradation of steroids by intestinal bacteria II. Biochim Biophys Acta 1970;202:535-43.","journal-title":"Biochim Biophys Acta"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0039-128X(78)90009-0","article-title":"Effect of pH on bile salt degradation by mixed fecal cultures","volume":"32","author":"MacDonald, I.A.; Singh, G.; Mahony, D.E.; Meier, C.E.","year":"1978","unstructured":"MacDonald IA, Singh G, Mahony DE, Meier CE. Effect of pH on bile salt degradation by mixed fecal cultures. Steroids 1978;32:245-56.","journal-title":"Steroids"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1136\/gut.15.12.999","article-title":"Effects of lactulose and other laxatives on ileal and colonic pH as measured by a radiotelemetry device","volume":"15","author":"Bown, R.L.; Gibson, J.A.; Sladen, G.E.; Hicks, B.; Dawson, A.M.","year":"1974","unstructured":"Bown RL, Gibson JA, Sladen GE, Hicks B, Dawson AM. Effects of lactulose and other laxatives on ileal and colonic pH as measured by a radiotelemetry device. Gut 1974;15:999-1004.","journal-title":"Gut"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/BF02239307","article-title":"Bile-rich duodenal fluid as an indicator of biliary lipid composition and its applicability to detection of lithogenic bile","volume":"16","author":"Vlahcevic, Z.R.; Bell, C.C.; Juttijudata, P.; Swell, L.","year":"1971","unstructured":"Vlahcevic ZR, Bell CC, Juttijudata P, Swell L. Bile-rich duodenal fluid as an indicator of biliary lipid composition and its applicability to detection of lithogenic bile. Am J Dig Dis 1971;16:797-802.","journal-title":"Am J Dig Dis"},{"issue":"28","key":"ref_11","volume":"282","author":"MEDICAL, B.R.I.T.I.S.H.","year":"1981","unstructured":"BRITISH MEDICAL JOURNAL VOLUME 282 28 MARCH 1981","journal-title":"JOURNAL VOLUME"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0009-8981(78)90222-X","article-title":"A simplified procedure for the analysis of cholesterol, phospholipids and bile salts in human bile","volume":"83","author":"Bolton, C.H.; Low-Beer, T.S.; Pomare, E.W.; Wicks, A.C.B.; Yeates, J.; Heaton, K.W.","year":"1978","unstructured":"Bolton CH, Low-Beer TS, Pomare EW, Wicks ACB, Yeates J, Heaton KW. A simplified procedure for the analysis of cholesterol, phospholipids and bile salts in human bile. Clin Chim Acta 1978;83:177-81.","journal-title":"Clin Chim Acta"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/BF02020933","article-title":"The solubility of cholesterol in aqueous solutions of bile salts and lecithin","volume":"10","author":"Hegardt, F.G.; Dam, H.","year":"1971","unstructured":"Hegardt FG, Dam H. The solubility of cholesterol in aqueous solutions of bile salts and lecithin. Z Ernachrungswiss 1971;10:223-33.","journal-title":"Z Ernachrungswiss"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/S0016-5085(79)80093-1","article-title":"Chenodeoxycholic acid desaturates bile-but how?","volume":"77","author":"Andersen, J.M.","year":"1979","unstructured":"Andersen JM. Chenodeoxycholic acid desaturates bile-but how? Gastroenterology 1979;77:1146-51.","journal-title":"Gastroenterology"},{"key":"ref_15","first-page":"315","article-title":"The selective inhibition of chenodeoxycholate synthesis by cholate metabolites in man","volume":"48","author":"Pomare, E.W.; Low-Beer, T.S.","year":"1975","unstructured":"Pomare EW, Low-Beer TS. The selective inhibition of chenodeoxycholate synthesis by cholate metabolites in man. Clinical Science and Molecular Medicine 1975; 48:315-21.","journal-title":"Clinical Science and Molecular Medicine"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S0022-2275(20)39841-2","article-title":"pH-solubility relations of chenodeoxycholic and ursodeoxycholic acids: physical-chemical basis for dissimilar solution and membrane phenomena","volume":"21","author":"Igimi, H.; Carey, M.C.","year":"1980","unstructured":"Igimi H, Carey MC. pH-solubility relations of chenodeoxycholic and ursodeoxycholic acids: physical-chemical basis for dissimilar solution and membrane phenomena. J Lipid Res 1980;21:72-90.","journal-title":"J Lipid Res"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0005-2760(68)90018-0","article-title":"Studies on the adsorption of bile salts to nonabsorbed components of diet","volume":"152","author":"Eastwood, M.A.; Hamilton, D.","year":"1968","unstructured":"Eastwood MA, Hamilton D. Studies on the adsorption of bile salts to nonabsorbed components of diet. Biochim Biophys Acta 1968;152:165-73.","journal-title":"Biochim Biophys Acta"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/BF01464757","article-title":"The -effect of wheat bran upon bile salt metabolism and upon the lipid composition of bile in gallstone patients. Am3'","volume":"21","author":"Pomare, E.W.; Heton, K.W.; Low-Beer, T.S.; Espiner, H.J.","year":"1976","unstructured":"Pomare EW, Heton KW, Low-Beer TS, Espiner HJ. The -effect of wheat bran upon bile salt metabolism and upon the lipid composition of bile in gallstone patients. Am3' Dig Dis 1976;21:521-6.","journal-title":"Dig Dis"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1093\/ajcn\/29.12.1468","article-title":"Changes in fecal composition and colonic function due to cereal fiber","volume":"29","author":"Cummings, J.H.; Hill, M.J.; Jenkins, D.J.A.; Pearson, JR, Wiggins; H.S.","year":"1976","unstructured":"Cummings JH, Hill MJ, Jenkins DJA, Pearson JR, Wiggins HS. Changes in fecal composition and colonic function due to cereal fiber. Am J Clin Nutr 1976;29:1468-73.","journal-title":"Am J Clin Nutr"},{"key":"ref_20","first-page":"141","article-title":"Chenodeoxycholic acid therapy of gallstones","volume-title":"in gastroenterology. Bile acids","author":"Dowling, R.H.","year":"1977","unstructured":"Dowling RH. Chenodeoxycholic acid therapy of gallstones. In: Paumgartner G, ed. Clinics in gastroenterology. Bile acids. London: W B Saunders Ltd, 1977:141-63."},{"key":"ref_21","author":"Accepted 15_7anuary 1981)","unstructured":"(Accepted 15_7anuary 1981)"},{"issue":"85","key":"ref_22","first-page":"738","article-title":"An evaluation of clinical signs in the diagnosis of venous thrombosis","volume":"1962","author":"McLachlin, J.; Richards, T.; Paterson, J.L.","unstructured":"McLachlin J, Richards T, Paterson JL. An evaluation of clinical signs in the diagnosis of venous thrombosis. Arch Surg 1962;85:738-44.","journal-title":"Arch Surg"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1177\/000331976902000406","article-title":"Problems of acute deep venous thrombosis. I. The interpretation of signs and symptoms","volume":"20","author":"Haeger, K.","year":"1969","unstructured":"Haeger K. Problems of acute deep venous thrombosis. I. The interpretation of signs and symptoms. Angiology 1969;20:219-22.","journal-title":"Angiology"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1055\/s-0028-1086125","article-title":"Diagnosis of venous thromboembolism","volume":"2","author":"Gallus, A.S.; Hirsh, J.; Hull, R.","year":"1976","unstructured":"Gallus AS, Hirsh J, Hull R, et al. Diagnosis of venous thromboembolism. Semin Thromb Haemostas 1976;2:203-25.","journal-title":"Semin Thromb Haemostas"},{"key":"ref_25","first-page":"33","article-title":"Diagnosis of venous thrombosis by invasive and noninvasive techniques","volume-title":"arterial thrombosis","author":"Hull, R.; Hirsh, J.","year":"1979","unstructured":"Hull R, Hirsh J. Diagnosis of venous thrombosis by invasive and noninvasive techniques. In: Joist JH, Sherman LA, eds. Venous and arterial thrombosis. New York: Grune and Stratton, 1979:33-56."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1093\/oxfordjournals.bmb.a071487","article-title":"Diagnosis of deep vein thrombosis","volume":"34","author":"Browse, N.L.","year":"1978","unstructured":"Browse NL. Diagnosis of deep vein thrombosis. Br Med Bull 1978;34: 163-7.","journal-title":"Br Med Bull"},{"key":"ref_27","first-page":"243","article-title":"Indium (11In)-labelled human platelets: optimal method","volume":"58","author":"Hawker, R.J.; Hawker, L.M.; Wilkinson, A.R.","year":"1980","unstructured":"Hawker RJ, Hawker LM, Wilkinson AR. Indium (11In)-labelled human platelets: optimal method. Clin Sci Mol Med 1980;58:243-8.","journal-title":"Clin Sci Mol Med"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/S0140-6736(68)90242-0","article-title":"Effect of anti-inflammatory agents on platelets","volume":"i:","author":"O'Brien, JR","year":"1968","unstructured":"O'Brien JR. Effect of anti-inflammatory agents on platelets. Lancet 1968;i:894-5.","journal-title":"Lancet"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/S0140-6736(78)90972-8","article-title":"Scintigraphic detection of atherosclerotic lesions and venous thrombi in man by indium-111 labelled autologous platelets","volume":"i:","author":"Davis, H.H.; Heaton, W.A.; Siegel, B.A.","year":"1978","unstructured":"Davis HH, Heaton WA, Siegel BA, et al. Scintigraphic detection of atherosclerotic lesions and venous thrombi in man by indium-111 labelled autologous platelets. Lancet 1978;i:1185-7.","journal-title":"Lancet"},{"key":"ref_30","first-page":"626","article-title":"Indium-llllabelled autologous platelets for location of vascular thrombi in humans","volume":"19","author":"Goodwin, D.A.; Bushberg, J.T.; Doherty, P.W.; Lipton, M.J.","year":"1978","unstructured":"Goodwin DA, Bushberg JT, Doherty PW, Lipton MJ, et al. Indium-llllabelled autologous platelets for location of vascular thrombi in humans. J Nucl Med 1978;19:626-34.","journal-title":"J Nucl Med"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1136\/bmj.280.6231.1571","article-title":"Indium-ill labelled platelets in diagnosis of leg vein thrombosis: prelimiinary findings","volume":"280","author":"Fenech, A.; Dendy, P.P.; Hussey, J.K.; Bennett, B.; Douglas, A.S.","year":"1980","unstructured":"Fenech A, Dendy PP, Hussey JK, Bennett B, Douglas AS. Indium-ill labelled platelets in diagnosis of leg vein thrombosis: prelimiinary findings. Br MedJ 1980;280:1571-3.","journal-title":"Br MedJ"},{"key":"ref_32","author":"Accepted 28,7anuary 1981)","unstructured":"(Accepted 28,7anuary 1981)"},{"key":"ref_33","article-title":"the undersigned inhabitants of the borough, do respectfully ask you to convene, at your earliest convenience, a public meeting, to protest emphatically against the late appointment of the medical officer of health against the general wish of the inhabitants, which we consider calculated to do infinite damage to the trade and prosperity of the town, by bringing disrepute upon it as a health-resort, which is assuredly evinced by strictures passed in the leading medical journals, and is thus brought under the notice of the profession, who will assuredly refrain from recommending their patients to come here if such appointment be maintained","volume":"1881","author":"We","unstructured":"We, the undersigned inhabitants of the borough, do respectfully ask you to convene, at your earliest convenience, a public meeting, to protest emphatically against the late appointment of the medical officer of health against the general wish of the inhabitants, which we consider calculated to do infinite damage to the trade and prosperity of the town, by bringing disrepute upon it as a health-resort, which is assuredly evinced by strictures passed in the leading medical journals, and is thus brought under the notice of the profession, who will assuredly refrain from recommending their patients to come here if such appointment be maintained. (British Medical Journal, 1881.)","journal-title":"(British Medical Journal"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.282.6269.1020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,3]],"date-time":"2021-10-03T22:21:03Z","timestamp":1633299663000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.282.6269.1020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,3,28]]},"references-count":33,"journal-issue":{"issue":"6269","published-print":{"date-parts":[[1981,3,28]]}},"URL":"https:\/\/doi.org\/10.1136\/bmj.282.6269.1020","relation":{},"ISSN":["0959-8138","1468-5833"],"issn-type":[{"value":"0959-8138","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,3,28]]}}}