{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:54:12Z","timestamp":1791352452364,"version":"4.3.1"},"reference-count":17,"publisher":"BMJ","issue":"6334","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ"],"published-print":{"date-parts":[[1982,7,3]]},"DOI":"10.1136\/bmj.285.6334.20","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T15:00:59Z","timestamp":1238684459000},"page":"20-21","source":"Crossref","is-referenced-by-count":179,"title":["Intestinal permeability in children with Crohn's disease and coeliac disease."],"prefix":"10.1136","volume":"285","author":[{"given":"A D","family":"Pearson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E J","family":"Eastham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M F","family":"Laker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A W","family":"Craft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1085\/jgp.45.4.801","article-title":"Permeability of luminal surface of intestinal mucosal cells","volume":"45","author":"Lindemann, B.; Solomon, A.K.","year":"1962","unstructured":"Lindemann B, Solomon AK. Permeability of luminal surface of intestinal mucosal cells. J Gen Physiol 1962;45:801-10.","journal-title":"J Gen Physiol"},{"key":"ref_2","first-page":"287","article-title":"Water and solute movements in the small intestine of patients with sprue. J7 Clin Invest","volume":"46","author":"Fordtran, J.S.; Rector, F.C.; Locklear, T.W.; Ewton, M.F.","year":"1976","unstructured":"Fordtran JS, Rector FC, Locklear TW, Ewton MF. Water and solute movements in the small intestine of patients with sprue. J7 Clin Invest 1976;46:287-98."},{"key":"ref_3","first-page":"1060","article-title":"Intestinal permeability assessed by the excretion ratio of two molecules results in coeliac disease","volume":"ii:","year":"1978","unstructured":"Cobden I, Dickinson RJ, Rothwell 1, Axon ATR. Intestinal permeability assessed by the excretion ratio of two molecules results in coeliac disease. Br Med J 1978;ii:1060-3.","journal-title":"Br Med J"},{"key":"ref_4","first-page":"1285","article-title":"Intestinal permeability in patients with eczema and food allergy","volume":"i:","author":"Jackson, P.G.; Lessof, M.H.; Baker, R.W.R.; Ferrett, J.; MacDonald, D.M.","year":"1981","unstructured":"Jackson PG, Lessof MH, Baker RWR, Ferrett J, MacDonald DM. Intestinal permeability in patients with eczema and food allergy. Lancet 1981;i:1285-6.","journal-title":"Lancet"},{"key":"ref_5","first-page":"117","article-title":"Gastrointestinal permeability changes in the preterm neonate","volume":"57","author":"Beach, R.C.; Menzies, I.S.; Clayden, G.S.; Scopes, J.W.","year":"1982","unstructured":"Beach RC, Menzies IS, Clayden GS, Scopes JW. Gastrointestinal permeability changes in the preterm neonate. Arch Dis Child 1982; 57:117-22.","journal-title":"Arch Dis Child"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0016-5085(75)80101-6","article-title":"Definition of inflammatory bowel disease of unknown aetiology","volume":"68","author":"Schachter, H.; Kirsner, J.B.","year":"1975","unstructured":"Schachter H, Kirsner JB. Definition of inflammatory bowel disease of unknown aetiology. Gastroenterology 1975;68:591-600.","journal-title":"Gastroenterology"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1093\/clinchem\/26.3.441","article-title":"Mannitol estimation in biological fluids by gas liquid chromatography of trimethsilyl derivatives","volume":"26","author":"Laker, M.F.; Mount, J.N.","year":"1980","unstructured":"Laker MF, Mount JN. Mannitol estimation in biological fluids by gas liquid chromatography of trimethsilyl derivatives. Clin Chem 1980; 26:441-3.","journal-title":"Clin Chem"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0378-4347(00)81163-9","article-title":"Estimation of disaccharides in plasma and urine by gas liquid chromatography","volume":"163","author":"Laker, M.F.","year":"1979","unstructured":"Laker MF. Estimation of disaccharides in plasma and urine by gas liquid chromatography. J Chromatogr 1979;163:9-18.","journal-title":"J Chromatogr"},{"key":"ref_9","article-title":"The effect of hypertonic solutions on the gastrointestinal permeability to disaccharide","author":"thesis, Laker MF. MD","year":"1978","unstructured":"Laker MF. MD thesis. The effect of hypertonic solutions on the gastrointestinal permeability to disaccharide. University of London, 1978."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1042\/bst0021042","article-title":"Absorption of intact oligosaccharides in health and disease","volume":"2","author":"Menzies, I.S.","year":"1974","unstructured":"Menzies IS. Absorption of intact oligosaccharides in health and disease. Biochem Soc Trans 1974;2:1042-6.","journal-title":"Biochem Soc Trans"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0926-6593(65)80082-0","article-title":"Inability of the human small intestinal lactose to hydrolyse lactulose","volume":"110","author":"Dahlqvist, A.; Gryboski, J.D.","year":"1965","unstructured":"Dahlqvist A, Gryboski JD. Inability of the human small intestinal lactose to hydrolyse lactulose. Biochim Bipohys Acta 1965;110:635-6.","journal-title":"Biochim Bipohys Acta"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/newbio235009a0","article-title":"Route of passive ion permeation in epithelia","volume":"235","author":"Fromter, E.; Diamond, J.","year":"1972","unstructured":"Fromter E, Diamond J. Route of passive ion permeation in epithelia. Nature New Biology 1972;235:9-13.","journal-title":"Nature New Biology"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1113\/jphysiol.1977.sp011750","article-title":"Increase in human intestinal permeability following ingestion of hypertonic solutions","volume":"265","author":"Laker, M.F.; Menzies, I.S.","year":"1977","unstructured":"Laker MF, Menzies IS. Increase in human intestinal permeability following ingestion of hypertonic solutions. Y Physiol 1977;265:881-94.","journal-title":"Y Physiol"},{"key":"ref_14","first-page":"495","article-title":"Effect of hyperosmolar stimuli and coeliac disease on the permeability of the human gastrointestinal tract","volume":"54","author":"Wheeler, P.G.; Menzies, I.S.; Creamer, B.","year":"1978","unstructured":"Wheeler PG, Menzies IS, Creamer B. Effect of hyperosmolar stimuli and coeliac disease on the permeability of the human gastrointestinal tract. Clinical Science and Molecular Medicine 1978;54:495-501.","journal-title":"Clinical Science and Molecular Medicine"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1136\/gut.21.6.512","article-title":"Intestinal permeability and screening tests for coeliac disease","volume":"21","author":"Cobden, I.; Rothwvell, J.; Axon, A.T.R.","year":"1980","unstructured":"Cobden I, Rothwvell J, Axon ATR. Intestinal permeability and screening tests for coeliac disease. Gut 1980;21:512-8.","journal-title":"Gut"},{"key":"ref_16","first-page":"208","article-title":"Passage of molecules through the wall of the gastrointestinal tract. II: Application of low molecular weight polyethyleneglycol and a deterministic mathematical model for determining intestinal permeability in man","volume-title":"Gut","volume":"21","author":"Sundqvist, T.; Magnusson, K.E.; Sjodahl, R.; Stjernstron, I.; Tagesson, C.","year":"1980","unstructured":"Sundqvist T, Magnusson KE, Sjodahl R, Stjernstron I, Tagesson C. Passage of molecules through the wall of the gastrointestinal tract. II: Application of low molecular weight polyethyleneglycol and a deterministic mathematical model for determining intestinal permeability in man. Gut 1980;21:208-14."},{"key":"ref_17","article-title":"Accepted","year":"1982","unstructured":"(Accepted 30 April 1982)"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.285.6334.20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T16:19:57Z","timestamp":1601050797000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.285.6334.20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,7,3]]},"references-count":17,"journal-issue":{"issue":"6334","published-print":{"date-parts":[[1982,7,3]]}},"URL":"https:\/\/doi.org\/10.1136\/bmj.285.6334.20","relation":{},"ISSN":["0959-8138","1468-5833"],"issn-type":[{"value":"0959-8138","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,7,3]]}}}