{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T17:51:31Z","timestamp":1765993891271,"version":"3.46.0"},"reference-count":13,"publisher":"BMJ","issue":"6344","license":[{"start":{"date-parts":[[1982,9,18]],"date-time":"1982-09-18T00:00:00Z","timestamp":401155200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J (Clin Res Ed)"],"published-print":{"date-parts":[[1982,9,18]]},"abstract":"<jats:p>\n                    A preliminary study of nuclear magnetic resonance imaging of the brains of four normal children (36 weeks' postmenstrual age to 5 years) showed long T\n                    <jats:sub>1<\/jats:sub>\n                    areas in the periventricular region of the neonate as well as evidence of progressive myelinisation with increasing age. Study of 18 patients of 40 weeks' postmenstrual age to 4 years showed an apparent deficit in myelinisation in an infant with probable rubella embryopathy and another with ventricular dilatation of unknown cause. Abnormal scans were obtained in an infant with congenital muscular dystrophy, and abnormalities were visualised at the lateral ventricular margins in a case of acute hydrocephalus after shunt blockage. Periventricular regions of increased T\n                    <jats:sub>2<\/jats:sub>\n                    were seen in a term infant aged 4 days after severe birth asphyxia and convulsions.\n                  <\/jats:p>\n                  <jats:p>Nuclear magnetic resonance imaging appears to provide a unique demonstration of myelinisation in vivo and shows changes in pathological processes of importance in paediatric practice.<\/jats:p>","DOI":"10.1136\/bmj.285.6344.774","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T11:00:59Z","timestamp":1238670059000},"page":"774-776","source":"Crossref","is-referenced-by-count":66,"title":["Nuclear magnetic resonance imaging of the brain in children"],"prefix":"10.1136","volume":"285","author":[{"given":"M I","family":"Levene","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Whitelaw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Dubowitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G M","family":"Bydder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R E","family":"Steiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C P","family":"Randell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I R","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1982,9,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0140-6736(81)90408-6","article-title":"Imaging of the brain by nuclear magnetic resonance","volume":"ii:","author":"Doyle, F.H.; Gore, J.C.; Pennock, J.M.","year":"1981","unstructured":"Doyle FH, Gore JC, Pennock JM, et al. Imaging of the brain by nuclear magnetic resonance. Lancet 1981;ii:53-7.","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"215","DOI":"10.2214\/ajr.139.2.215","article-title":"Clinical NMR imaging of the brain: 140 cases","volume":"139","author":"Bydder, G.M.; Steiner, R.E.; Young, I.R.","year":"1982","unstructured":"Bydder GM, Steiner RE, Young IR, et al. Clinical NMR imaging of the brain: 140 cases. AJR 1982;139:215-36.","journal-title":"AJR"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S0009-9260(82)80307-3","article-title":"NMR imaging of the brain using spin-echo sequences","volume":"33","author":"Bailes, D.R.; Young, I.R.; Thomas, D.J.; Straughan, K.; Bydder, G.M.; Steiner, R.E.","year":"1982","unstructured":"Bailes DR, Young IR, Thomas DJ, Straughan K, Bydder GM, Steiner RE. NMR imaging of the brain using spin-echo sequences. Clin Radiol 1982;33:395-414.","journal-title":"Clin Radiol"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1136\/adc.56.6.416","article-title":"Cerebral structure and intraventricular haemorrhage in the neonate: a real-time ultrasound study","volume":"56","author":"Levene, M.I.; Wigglesworth, J.S.; Dubowitz, V.","year":"1981","unstructured":"Levene MI, Wigglesworth JS, Dubowitz V. Cerebral structure and intraventricular haemorrhage in the neonate: a real-time ultrasound study. Arch Dis Child 1981;56:416-24.","journal-title":"Arch Dis Child"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00004728-198202000-00001","article-title":"Initial clinical evaluation of a whole body NMR tomograph","volume":"6","author":"Young, I.R.; Bailes, D.R.; Burl, M.","year":"1982","unstructured":"Young IR, Bailes DR, Burl M, et al. Initial clinical evaluation of a whole body NMR tomograph. J Comput Assist Tomogr 1982;6:1-18.","journal-title":"J Comput Assist Tomogr"},{"key":"ref_6","first-page":"147","article-title":"Central nervous system","author":"Smith, J.F.","year":"1981","unstructured":"Smith JF. Central nervous system. In: Berry CL, ed. Paediatric pathology. Berlin: Springer Verlag, 1981:147-8."},{"key":"ref_7","first-page":"744","article-title":"The later development of the brain and its vulnerability","volume-title":"foundations of paediatrics","author":"Dobbing, J.","year":"1982","unstructured":"Dobbing J. The later development of the brain and its vulnerability. In: Davis JA, Dobbing J, eds. Scientific foundations of paediatrics. London: William Heinemann Medical Books Ltd, 1982:744-59."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1136\/adc.48.10.757","article-title":"Quantitative growth and development of human brain","volume":"48","author":"Dobbing, J.; Sands, J.","year":"1973","unstructured":"Dobbing J, Sands J. Quantitative growth and development of human brain. Arch Dis Child 1973;48:757-67.","journal-title":"Arch Dis Child"},{"key":"ref_9","first-page":"162","article-title":"Myelination and diseases of the nervous system: abnormalities of myelin composition","author":"Davison, A.N.","year":"1970","unstructured":"Davison AN. Myelination and diseases of the nervous system: abnormalities of myelin composition. In: Davison AN, Peters A, eds. Myelination. Springfield, USA: Charles C Thomas, 1970:162-82."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/00004728-198012000-00008","article-title":"CT diagnosis and short-term prognosis of intracranial hemorrhage and hypoxic\/ischemic brain damage in neonates","volume":"4","author":"Flodmark 0, Fitz CR, Harwood-Nash DC","year":"1980","unstructured":"Flodmark 0, Fitz CR, Harwood-Nash DC. CT diagnosis and short-term prognosis of intracranial hemorrhage and hypoxic\/ischemic brain damage in neonates. J Comput Assist Tomogr 1980;4:775-87.","journal-title":"J Comput Assist Tomogr"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1097\/00004728-198112000-00003","article-title":"Nuclear magnetic resonance (NMR) in vivo studies: known thresholds for health effects","volume":"5","author":"Budinger, T.F.","year":"1981","unstructured":"Budinger TF. Nuclear magnetic resonance (NMR) in vivo studies: known thresholds for health effects. J Comput Assist Tomogr 1981;5: 800-11.","journal-title":"J Comput Assist Tomogr"},{"key":"ref_12","first-page":"65","article-title":"The biological hazards of NMR","author":"Saunders, R.D.","year":"1982","unstructured":"Saunders RD. The biological hazards of NMR. In: Witcofski RL, Karstaedt N, Partain CL, eds. NMR imaging. Winston-Salem, USA: Bowman Gray School of Medicine of Wake Forrest University, 1982: 65-71."},{"article-title":"Accepted","year":"1982","key":"ref_13","unstructured":"(Accepted 16 July 1982)"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.285.6344.774","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.285.6344.774","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T18:36:08Z","timestamp":1765305368000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.285.6344.774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,9,18]]},"references-count":13,"journal-issue":{"issue":"6344","published-online":{"date-parts":[[1982,9,18]]},"published-print":{"date-parts":[[1982,9,18]]}},"alternative-id":["10.1136\/bmj.285.6344.774"],"URL":"https:\/\/doi.org\/10.1136\/bmj.285.6344.774","relation":{},"ISSN":["0007-1447","1468-5833"],"issn-type":[{"type":"print","value":"0007-1447"},{"type":"electronic","value":"1468-5833"}],"subject":[],"published":{"date-parts":[[1982,9,18]]}}}