{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:10:58Z","timestamp":1792141858406,"version":"4.4.0"},"reference-count":10,"publisher":"BMJ","issue":"6362","license":[{"start":{"date-parts":[[1983,1,29]],"date-time":"1983-01-29T00:00:00Z","timestamp":412646400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J (Clin Res Ed)"],"published-print":{"date-parts":[[1983,1,29]]},"abstract":"<jats:p>The results of 3000 consecutive operations using cardio-pulmonary bypass show that the overall early mortality was 6.1%, dropping from 8.9% in the first 1000 to 4.4% in the third 1000. Operations for valve disease have been the most common, the early mortality for aortic valve replacement being 3.1% and for mitral valve replacement 2.9%. Combined aortic and mitral valve replacement had an early mortality of 4.4%. The number of patients undergoing isolated coronary artery bypass grafting has increased from 59 in the first 1000 to 292 in the third 1000 operations, with an overall early mortality of 1.3%. Six hundred and ninety seven patients underwent surgery for congenital heart disease with an overall early mortality of 10.9% (7.5% in the last 2000 cases). The patients have been followed up from one to 8.5 years. A high proportion have returned to work and enjoy a normal life. At the time of review, 87% of the 3000 patients were alive. Long waiting times for outpatient and inpatient care indicate underprovision of facilities relative to regional demand.<\/jats:p>","DOI":"10.1136\/bmj.286.6362.361","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T11:00:59Z","timestamp":1238670059000},"page":"361-365","source":"Crossref","is-referenced-by-count":6,"title":["Cardiac surgery in Wessex."],"prefix":"10.1136","volume":"286","author":[{"given":"J L","family":"Monro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J K","family":"Ross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J M","family":"Manners","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J C","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Hyde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B C","family":"Ogilvie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B R","family":"Keeton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Conway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A M","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1983,1,29]]},"reference":[{"key":"ref_1","first-page":"1485","article-title":"Cardiac surgery in Wessex: review of 1000 consecutive open-heart procedures","volume":"ii:","author":"Ross, J.K.; Monro, J.L.; Manners, J.M.","year":"1976","unstructured":"Ross JK, Monro JL, Manners JM, et al. Cardiac surgery in Wessex: review of 1000 consecutive open-heart procedures. Br Med Jf 1976;ii: 1485-9.","journal-title":"Br Med Jf"},{"key":"ref_2","first-page":"179","article-title":"Anaesthesia for cardiac surgery","volume-title":"reviews in anaesthesia","author":"Manners, J.M.","year":"1980","unstructured":"Manners JM. Anaesthesia for cardiac surgery. In: Normal J, Whitwham J, eds. Topical reviews in anaesthesia. Bristol: Wright Publisher, 1980: 179-259."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1161\/01.RES.36.4.481","article-title":"Hypothermia arrest and potassium arrest: metabolic and myocardial protection during elective cardiac arrest","volume":"36","author":"Hearse, D.J.; Stewart, D.A.; Braimbridge, M.V.","year":"1975","unstructured":"Hearse DJ, Stewart DA, Braimbridge MV. Hypothermia arrest and potassium arrest: metabolic and myocardial protection during elective cardiac arrest. Circulation Research 1975;36:481-9.","journal-title":"Circulation Research"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1111\/j.1365-2044.1980.tb05071.x","article-title":"Corrective surgery in infants","volume":"35","author":"Manners, J.M.; Monro, J.L.; Edwards, J.C.","year":"1980","unstructured":"Manners JM, Monro JL, Edwards JC. Corrective surgery in infants. Anaesthesia 1980;35:1149-56.","journal-title":"Anaesthesia"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1136\/bmj.284.6321.995","article-title":"Long term complications of valve replacement","volume":"284","author":"Oakley, C.M.","year":"1982","unstructured":"Oakley CM. Long term complications of valve replacement. Br Med J 1982;284:995-7.","journal-title":"Br Med J"},{"key":"ref_6","first-page":"211","article-title":"Second report of a Joint Cardiology Committee of the Royal College of Physicians of London and the Royal College of Surgeons of England on combined cardiac centres for investigation and treatment with a note on the requirements of cardiology in hospital outside such a centre. Br Heart j 1980; 43","unstructured":"Second report of a Joint Cardiology Committee of the Royal College of Physicians of London and the Royal College of Surgeons of England on combined cardiac centres for investigation and treatment with a note on the requirements of cardiology in hospital outside such a centre. Br Heart j 1980;43:211-9."},{"key":"ref_7","article-title":"Accepted 26","year":"1982","unstructured":"(Accepted 26 November 1982)"},{"key":"ref_8","article-title":"PSEUDOMEMBRANOUS COLITIS DUE TO TETRACYCLINES-DRUGS MARKETED 1949; NO REGULATORY WARNING","volume-title":"IN UK","unstructured":"PSEUDOMEMBRANOUS COLITIS DUE TO TETRACYCLINES-DRUGS MARKETED 1949; NO REGULATORY WARNING IN UK"},{"key":"ref_9","article-title":"MARKETED 1964; UK REGULATORY WARNINGS 1976 AND","year":"1979","unstructured":"MARKETED 1964; UK REGULATORY WARNINGS 1976 AND 1979"},{"key":"ref_10","article-title":"PSEUDOMEMBRANOUS COLITIS DUE TO CLINDAMYCIN-DRUG MARKETED 1968; UK REGULATORY WARNINGS 1976 AND","year":"1979","unstructured":"PSEUDOMEMBRANOUS COLITIS DUE TO CLINDAMYCIN-DRUG MARKETED 1968; UK REGULATORY WARNINGS 1976 AND 1979"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.286.6362.361","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.286.6362.361","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T20:13:03Z","timestamp":1765311183000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.286.6362.361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,1,29]]},"references-count":10,"journal-issue":{"issue":"6362","published-online":{"date-parts":[[1983,1,29]]},"published-print":{"date-parts":[[1983,1,29]]}},"alternative-id":["10.1136\/bmj.286.6362.361"],"URL":"https:\/\/doi.org\/10.1136\/bmj.286.6362.361","relation":{},"ISSN":["0007-1447","1468-5833"],"issn-type":[{"value":"0007-1447","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,1,29]]}}}