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All the obese women showed a decrease in haemoglobin oxygen saturation when asleep, which occurred predominantly during periods of rapid eye movement sleep. That the fall in oxygen saturation was significantly greater (p less than 0.05) in the obese non-responders suggests that central as well as mechanical factors may be important for the genesis of nocturnal hypoxia and is evidence for a disturbance of central nervous function in some obese women.<\/jats:p>","DOI":"10.1136\/bmj.287.6396.859","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T11:00:59Z","timestamp":1238670059000},"page":"859-861","source":"Crossref","is-referenced-by-count":8,"title":["Nocturnal hypoxia and prolactin secretion in obese women."],"prefix":"10.1136","volume":"287","author":[{"given":"P G","family":"Kopelman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M C","family":"Apps","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Cope","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D W","family":"Empey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1983,9,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1056\/NEJM197903083001001","article-title":"Sleep apnea, hypoapnea and oxygen desaturation in normal subjects","volume":"300","author":"Block, A.J.; Boysen, P.G.; Wynne, J.W.; Hunt, L.A.","year":"1979","unstructured":"Block AJ, Boysen PG, Wynne JW, Hunt LA. 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