{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T20:16:52Z","timestamp":1765397812826,"version":"3.46.0"},"reference-count":6,"publisher":"BMJ","issue":"6420","license":[{"start":{"date-parts":[[1984,3,17]],"date-time":"1984-03-17T00:00:00Z","timestamp":448329600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J (Clin Res Ed)"],"published-print":{"date-parts":[[1984,3,17]]},"abstract":"<jats:p>A previously healthy woman developed streptococcal cellulitis of the leg after falling and lacerating her knee. On admission her blood pressure was unrecordable and her respiratory rate greater than 60 beats\/minute. Mechanical ventilation was necessary, and plasma volume expansion was started, with little effect. Infusion of dopamine restored the blood pressure to 150\/90 mm Hg, but interrupting the infusion for as little as 30 seconds resulted in profound hypotension. Insertion of a second central venous catheter allowed the dopamine to be given continuously, and the infusion was stopped successfully four days after her admission. She eventually made a complete recovery. This case highlights the need for intensive supportive treatment in many streptococcal infections and, in particular, the need for inotropic support.<\/jats:p>","DOI":"10.1136\/bmj.288.6420.816","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T11:00:59Z","timestamp":1238670059000},"page":"816-817","source":"Crossref","is-referenced-by-count":9,"title":["Myocardial depression in streptococcal cellulitis."],"prefix":"10.1136","volume":"288","author":[{"given":"J D","family":"Edwards","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P M","family":"Schofield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1984,3,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1136\/bmj.281.6252.1412","article-title":"Fulminant streptococcus pyogenes infection","volume":"281","author":"Goepel, JR, Richards; DG, Harris; DM, Henry; L.","year":"1980","unstructured":"Goepel JR, Richards DG, Harris DM, Henry L. Fulminant streptococcus pyogenes infection. Br MedJ 1980;281:1412.","journal-title":"Br MedJ"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1136\/bmj.282.6280.1944","article-title":"Fatal streptococcal septicaemia","volume":"282","author":"Cruickshank, J.G.; Hart, R.J.C.; George, M.; Feest, T.G.","year":"1981","unstructured":"Cruickshank JG, Hart RJC, George M, Feest TG. Fatal streptococcal septicaemia. Br MedJ 1981;282:1944-5.","journal-title":"Br MedJ"},{"key":"ref_3","first-page":"223","article-title":"Presence of a myocardial depressant factor in patients in circulatory shock","volume":"70","author":"Lovett, W.L.; Wangensteen, S.L.; Glenn, T.M.; Lefer, A.M.","year":"1971","unstructured":"Lovett WL, Wangensteen SL, Glenn TM, Lefer AM. Presence of a myocardial depressant factor in patients in circulatory shock. Surgery 1971;70:223-31.","journal-title":"Surgery"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1161\/01.RES.32.2.129","article-title":"Blood-borne humoral factors in the pathophysiology of circulatory shock","volume":"32","author":"Lefer, A.M.","year":"1973","unstructured":"Lefer AM. Blood-borne humoral factors in the pathophysiology of circulatory shock. Circ Res 1973;32:129-39.","journal-title":"Circ Res"},{"article-title":"Accepted","year":"1983","key":"ref_5","unstructured":"(Accepted 9 December 1983)"},{"key":"ref_6","unstructured":"Idiopathic orthostatic hypotension may occur either as an isolated disorder or in association with multiple defects of the central nervous system when it is known as the Shy-Drager syndrome. Treatment of this disabling condition is often unsatisfactory.' We report the effects of prenalterol, a selective adrenoceptor agonist,2 in a patient with the Shy-Drager syndrome.","article-title":"Idiopathic orthostatic hypotension may occur either as an isolated disorder or in association with multiple defects of the central nervous system when it is known as the Shy-Drager syndrome. Treatment of this disabling condition is often unsatisfactory.' We report the effects of prenalterol, a selective adrenoceptor agonist,2 in a patient with the Shy-Drager syndrome"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.288.6420.816","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.288.6420.816","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T20:15:06Z","timestamp":1765397706000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.288.6420.816"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,3,17]]},"references-count":6,"journal-issue":{"issue":"6420","published-online":{"date-parts":[[1984,3,17]]},"published-print":{"date-parts":[[1984,3,17]]}},"alternative-id":["10.1136\/bmj.288.6420.816"],"URL":"https:\/\/doi.org\/10.1136\/bmj.288.6420.816","relation":{},"ISSN":["0007-1447","1468-5833"],"issn-type":[{"type":"print","value":"0007-1447"},{"type":"electronic","value":"1468-5833"}],"subject":[],"published":{"date-parts":[[1984,3,17]]}}}