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The yield of positive findings and need for operation were greater in those referred after one infection than in those with recurrent infection. Among those under 2 years old 90% had an abnormality. One third of children with vesicoureteric reflux showed renal scarring at the time of first attendance. The results of medical and surgical treatment over five to 15 years of follow up were analysed. They emphasised the importance of culturing the urine whenever there may be urinary infection in a child and of investigating immediately those with a positive urine culture.<\/jats:p>","DOI":"10.1136\/bmj.289.6440.299","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T11:00:59Z","timestamp":1238670059000},"page":"299-303","source":"Crossref","is-referenced-by-count":58,"title":["Urinary tract infection in children."],"prefix":"10.1136","volume":"289","author":[{"given":"W","family":"McKerrow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Davidson-Lamb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P F","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1984,8,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1136\/adc.50.4.253","article-title":"Urinary tract infection in schoolgirls with covert bacteriuria","volume":"50","author":"McLachlan, M.S.F.; Meller, S.T.; Verrier-Jones, E.R.","year":"1975","unstructured":"McLachlan MSF, Meller ST, Verrier-Jones ER, et al. Urinary tract infection in schoolgirls with covert bacteriuria. Arch Dis Child 1975;50:253-8.","journal-title":"Arch Dis Child"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1038\/ki.1981.201","article-title":"Children with urinary infection: a comparison of those with and those without vesicoureteric reflux","volume":"20","author":"Smellie, J.M.; Normand, I.C.S.; Katz, G.","year":"1981","unstructured":"Smellie JM, Normand ICS, Katz G. Children with urinary infection: a comparison of those with and those without vesicoureteric reflux. Kidney Int 1981;20: 717-22.","journal-title":"Kidney Int"},{"key":"ref_3","first-page":"678","article-title":"Symptomatic urinary infection in childhood: presentation during a four year study in general practice, and significance and outcome","volume":"27","author":"Brooks, D.; Houston, I.B.","year":"1977","unstructured":"Brooks D, Houston IB. Symptomatic urinary infection in childhood: presentation during a four year study in general practice, and significance and outcome at 7 years. J R Coll Gen Pract 1977;27:678-83.","journal-title":"J R Coll Gen Pract"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1136\/bmj.1.5694.460","article-title":"Relationship of infantile vesicoureteric reflux to renal damage","volume":"i:","author":"Rolleston, G.L.; Shannon, F.T.; Utley, W.L.F.","year":"1970","unstructured":"Rolleston GL, Shannon FT, Utley WLF. Relationship of infantile vesicoureteric reflux to renal damage. Br MedJa 1970;i:460-3.","journal-title":"Br MedJa"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/j.1464-410X.1977.tb04543.x","article-title":"Ureteric advancement in the treatment of reflux","volume":"49","author":"Jones, P.F.","year":"1977","unstructured":"Jones PF. Ureteric advancement in the treatment of reflux. Br J Urol 1977;49: 629-32.","journal-title":"Br J Urol"},{"key":"ref_6","first-page":"340","article-title":"Urinary tract infection in children: general practice survey","volume":"5","author":"Williams, C.M.","year":"1976","unstructured":"Williams CM. Urinary tract infection in children: general practice survey. Aust Fam Physician 1976;5:340-4.","journal-title":"Aust Fam Physician"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1136\/bmj.1.6174.1330","article-title":"Incidence and outcome of symptomatic urinary tract infection in children","volume":"i:","author":"Dickinson, J.A.","year":"1979","unstructured":"Dickinson JA. Incidence and outcome of symptomatic urinary tract infection in children. Br Med J 1979;i:1330-2.","journal-title":"Br Med J"},{"key":"ref_8","first-page":"353","article-title":"Urinary tract infection in children: a survey of management","volume":"33","author":"Potts, SR, Irwin; W.G.","year":"1983","unstructured":"Potts SR, Irwin WG. Urinary tract infection in children: a survey of management. J R Coll Gen Pract 1983;33:353-5.","journal-title":"J R Coll Gen Pract"},{"key":"ref_9","first-page":"132","article-title":"The relationship of vesico-ureteric reflux to urinary tract infection and chronic pyelonephritis-reflux nephropathy","volume":"1","author":"Bailey, R.R.","year":"1973","unstructured":"Bailey RR. The relationship of vesico-ureteric reflux to urinary tract infection and chronic pyelonephritis-reflux nephropathy. Clin Nephrol 1973;1:132-41.","journal-title":"Clin Nephrol"},{"key":"ref_10","first-page":"282","article-title":"Urinary tract infection in infancy","volume":"75","author":"Shannon, F.T.","year":"1972","unstructured":"Shannon FT. Urinary tract infection in infancy. NZ Med J 1972;75:282-5.","journal-title":"NZ Med J"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1464-410X.1983.tb06560.x","article-title":"Too many cystograms in the investigation of urinary tract infection in childhood?","volume":"55","author":"Cavanagh, P.M.; Sherwood, T.","year":"1983","unstructured":"Cavanagh PM, Sherwood T. Too many cystograms in the investigation of urinary tract infection in childhood? Br J Urol 1983;55:217-9.","journal-title":"Br J Urol"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0022-3468(82)80324-2","article-title":"Computer analysis of micturating cysto-urethrograms in children","volume":"17","author":"Buick, R.G.; O'Donnell, B.; McAllinden, A.","year":"1982","unstructured":"Buick RG, O'Donnell B, McAllinden A. Computer analysis of micturating cysto-urethrograms in children. J Pediatr Surg 1982;17:48-51.","journal-title":"J Pediatr Surg"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/j.1464-410X.1978.tb06194.x","article-title":"The management of vesicoureteric reflux in children","volume":"50","author":"Dunn, M.; Slade, N.; Gumpert, J.R.W.; Smith, P.J.B.; Dounis, A.","year":"1978","unstructured":"Dunn M, Slade N, Gumpert JRW, Smith PJB, Dounis A. The management of vesicoureteric reflux in children. Br J Urol 1978;50:474-78.","journal-title":"Br J Urol"},{"key":"ref_14","first-page":"\"171","article-title":"Long term low dose cotrimoxazole in prophylaxis of childhood urinary tract infections: clinical aspects. Br MedJa 1976; ii: 203-6. tBirmingham Reflux Study Group. Prospective trial of operative versus nonoperative treatment of severe vesicoureteric reflux: two years' observation in 96 children","volume":"287","author":"Smellie, J.M.; Gruneberg, R.N.; Leakey, A.; Atkin, W.S.","year":"1983","unstructured":"Smellie JM, Gruneberg RN, Leakey A, Atkin WS. Long term low dose cotrimoxazole in prophylaxis of childhood urinary tract infections: clinical aspects. Br MedJa 1976;ii:203-6. tBirmingham Reflux Study Group. Prospective trial of operative versus nonoperative treatment of severe vesicoureteric reflux: two years' observation in 96 children. Br Med J 1983;287:171-4. 16\"Report of the International Reflux Study Committee. Medical versus surgical treatment of primary vesicoureteral reflux: a prospective international reflux study in children. Y Urol 1983;125:277-83. \" Kincaid-Smith P. Reflux nephropathy. Br Med J 1983;286:2002-3.","journal-title":"Br Med J; 16\"Report of the International Reflux Study Committee. 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