{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T22:30:51Z","timestamp":1765405851393,"version":"3.46.0"},"reference-count":15,"publisher":"BMJ","issue":"6445","license":[{"start":{"date-parts":[[1984,9,8]],"date-time":"1984-09-08T00:00:00Z","timestamp":463449600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J (Clin Res Ed)"],"published-print":{"date-parts":[[1984,9,8]]},"abstract":"<jats:p>Twenty patients with postpartum hypopituitarism underwent a dehydration test followed by the administration of synthetic arginine-vasopressin (DDAVP; desmopressin). Panhypopituitarism was confirmed by hormonal assays in the basal state and after stimulation with combined luteinising hormone releasing hormone-thyrotrophin releasing hormone-insulin. All the patients were given replacement therapy with hydrocortisone and thyroid hormones. Results were compared with those in 12 normal women. Urinary concentrating ability was diminished in the patients as compared with the controls (maximum urine osmolality 688 (SEM 23) mmol (mosmol)\/kg in the patients v 967 (SEM 29) mmol\/kg in the controls). Also the change in urine osmolality after administration of desmopressin was greater in the patients (+9.55 (SEM 1.98)% in the patients v 2.49 (SEM 0.96)% in the controls). Partial diabetes insipidus is apparently common in Sheehan's syndrome. This association should be borne in mind when managing these patients, especially those in acute failure.<\/jats:p>","DOI":"10.1136\/bmj.289.6445.579","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T11:00:59Z","timestamp":1238670059000},"page":"579-580","source":"Crossref","is-referenced-by-count":18,"title":["Antidiuretic function in Sheehan's syndrome."],"prefix":"10.1136","volume":"289","author":[{"given":"F","family":"Bakiri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Benmiloud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1984,9,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/path.1700850115","article-title":"The neurohypophysis in post-partum hypopituitarism","volume":"85","author":"Sheehan, H.L.; Whitehead, R.","unstructured":"Sheehan HL, Whitehead R. The neurohypophysis in post-partum hypopituitarism. Journal of Pathology and Bacteriology 1963 -85:145-69.","journal-title":"Journal of Pathology and Bacteriology 1963 -"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/path.1700860107","article-title":"The hypothalamus in post-partum hypopituitarism","volume":"86","author":"Whitehead, R.","year":"1963","unstructured":"Whitehead R. The hypothalamus in post-partum hypopituitarism. Journal of Pathology and Bacteriology 1963;86:55-67.","journal-title":"Journal of Pathology and Bacteriology"},{"issue":"60","key":"ref_3","first-page":"7","article-title":"Diabetes insipidus syndrome in hypopituitarism of pregnancy","volume":"1969","unstructured":"Aguilo F, Vega LA, Haddock L, Rodriguez 0. Diabetes insipidus syndrome in hypopituitarism of pregnancy. Acta Endocrinol (Copenh) 1969;60 (suppl 137): 7-32.","journal-title":"Acta Endocrinol (Copenh)"},{"key":"ref_4","first-page":"123","article-title":"Hypopituitarisme par necrose du post-partum, associe a un diabete insipide. Commentaire a propos d'un cas","volume":"13","author":"Marti-Henneberg, C.; Gonzalez-Alvarez, M.T.; Audi Parera, L.; Vilardell, E.","year":"1972","unstructured":"Marti-Henneberg C, Gonzalez-Alvarez MT, Audi Parera L, Vilardell E. Hypopituitarisme par necrose du post-partum, associe a un diabete insipide. Commentaire a propos d'un cas. Revue Francaise d'Endocrinologie Clinique 1972;13: 123-9.","journal-title":"Revue Francaise d'Endocrinologie Clinique"},{"key":"ref_5","first-page":"431","article-title":"Sheehan's syndrome with diabetes insipidus. A case study","volume":"15","author":"Weiner, P.; Ben-Israel, J.; Plavnick, L.","year":"1979","unstructured":"Weiner P, Ben-Israel J, Plavnick L. Sheehan's syndrome with diabetes insipidus. A case study. IsrJ7 Med Sci 1979;15:431-3.","journal-title":"IsrJ7 Med Sci"},{"key":"ref_6","first-page":"16","volume":"53","author":"Gynecol, Obstet","year":"1979","unstructured":"Obstet Gynecol 1979;53 (suppl): 16-7."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1136\/bmj.280.6206.20","article-title":"Postpartum cranial diabetes insipidus","volume":"280","author":"Baylis, P.M.; Mllles, J.J.; London, D.R.; Butt, W.R.","year":"1980","unstructured":"Baylis PM, Mllles JJ, London DR, Butt WR. Postpartum cranial diabetes insipidus. Br MedJ 1980;280:20.","journal-title":"Br MedJ"},{"key":"ref_8","first-page":"321","article-title":"Post-partum pituitary insufficiency (Sheehan's syndrome): review of 18 cases","volume-title":"Mayo Clin Proc 1964","volume":"39","author":"Purnell, D.C.; Randall, R.V.; Rynearson, E.H.","unstructured":"Purnell DC, Randall RV, Rynearson EH. Post-partum pituitary insufficiency (Sheehan's syndrome): review of 18 cases. Mayo Clin Proc 1964;39:321-31."},{"key":"ref_9","first-page":"80","volume":"131","author":"Medical_Journal","year":"1972","unstructured":"Medical_Journal 1972;131:80-99."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"721","DOI":"10.7326\/0003-4819-73-5-721","article-title":"Recognition of partial defects in antidiuretic hormone secretion","volume":"73","author":"Miller, M.; Dalakos, T.; Moses, A.M.; Fellerman, H.; Streeten, D.H.","year":"1970","unstructured":"Miller M, Dalakos T, Moses AM, Fellerman H, Streeten DH. Recognition of partial defects in antidiuretic hormone secretion. Ann Intern Med 1970;73: 721-9.","journal-title":"Ann Intern Med"},{"key":"ref_11","article-title":"Disorders of the neurohypophysis","volume-title":"Harrison's principles of internal medicine","author":"Streeten, D.H.; Moses, A.M.; Miller, M.","unstructured":"Streeten DH, Moses AM, Miller M. Disorders of the neurohypophysis. In: Isselbacher KI, Adams RD, Braunwald E, Petersdorf RG, Wilson JD, eds. Harrison's principles of internal medicine. 9th ed. New York: McGraw Hill, 1980:1684."},{"key":"ref_12","first-page":"831","volume":"59","author":"Wochenschr, Klin","year":"1981","unstructured":"Klin Wochenschr 1981;59:831-6."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1056\/NEJM198112243052601","article-title":"A comparison of plasma vasopressin measurements with a standard indirect test in the differential diagnosis of polyuria","volume":"305","author":"Zerbe, R.L.; Robertsen, G.L.","year":"1981","unstructured":"Zerbe RL, Robertsen GL. A comparison of plasma vasopressin measurements with a standard indirect test in the differential diagnosis of polyuria. N Engl J Med 1981;305:1539-46.","journal-title":"N Engl J Med"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1530\/acta.0.1040410","article-title":"A comparison of diagnostic methods to differentiate diabetes insipidus from primary polyuria: a review of 21 patients","volume":"105","author":"Milles, J.J.; Spruce, B.; Baylis, P.H.","year":"1983","unstructured":"Milles JJ, Spruce B, Baylis PH. A comparison of diagnostic methods to differentiate diabetes insipidus from primary polyuria: a review of 21 patients. Acta Endocrinol (Copenh) 1983;105:410-6.","journal-title":"Acta Endocrinol (Copenh)"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1210\/jcem-58-3-511","article-title":"Arginine-vasopressin in postpartum panhypopituitarism: urinary excretion and kidney response to osmolar load","volume":"58","author":"Bakiri, F.; Benmniloud, M.; Vallotton, M.B.","year":"1984","unstructured":"Bakiri F, Benmniloud M, Vallotton MB. Arginine-vasopressin in postpartum panhypopituitarism: urinary excretion and kidney response to osmolar load. 7 Clin Endocrinol Metab 1984;58:511-5 (Accepted 15,June 1984)","journal-title":"7 Clin Endocrinol Metab"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.289.6445.579","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.289.6445.579","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T22:26:14Z","timestamp":1765405574000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.289.6445.579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,9,8]]},"references-count":15,"journal-issue":{"issue":"6445","published-online":{"date-parts":[[1984,9,8]]},"published-print":{"date-parts":[[1984,9,8]]}},"alternative-id":["10.1136\/bmj.289.6445.579"],"URL":"https:\/\/doi.org\/10.1136\/bmj.289.6445.579","relation":{},"ISSN":["0007-1447","1468-5833"],"issn-type":[{"type":"print","value":"0007-1447"},{"type":"electronic","value":"1468-5833"}],"subject":[],"published":{"date-parts":[[1984,9,8]]}}}