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The heart rate at all levels of exercise in most patients with atrial fibrillation was not adequately controlled by any serum digoxin concentration tested despite a reduction in heart rate with increasing serum digoxin concentrations. Control of the resting heart rate, even in patients with high serum digoxin concentrations, did not ensure adequate control of the heart rate during work rates equivalent to regular daily activities.<\/jats:p>","DOI":"10.1136\/bmj.290.6461.9","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T11:00:59Z","timestamp":1238670059000},"page":"9-11","source":"Crossref","is-referenced-by-count":80,"title":["Exercise heart rates at different serum digoxin concentrations in patients with atrial fibrillation."],"prefix":"10.1136","volume":"290","author":[{"given":"R","family":"Beasley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D A","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D J","family":"McHaffie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1985,1,5]]},"reference":[{"key":"ref_1","first-page":"417","article-title":"The use of digitalis glvcosides in sinus rhythm","volume":"55","author":"Guz, A.; McHaffie, D.","year":"1978","unstructured":"Guz A, McHaffie D. 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