{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T18:43:49Z","timestamp":1765478629302,"version":"3.48.0"},"reference-count":6,"publisher":"BMJ","issue":"6499","license":[{"start":{"date-parts":[[1985,9,28]],"date-time":"1985-09-28T00:00:00Z","timestamp":496713600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J (Clin Res Ed)"],"published-print":{"date-parts":[[1985,9,28]]},"abstract":"<jats:p>A case of coronary artery vasospasm was studied in a man with a four year history of angina. He had evidence of symptomatic hyperventilation during a spontaneous episode of chest pain. When asked to hyperventilate the pain in his chest and ST elevation were reproduced in the same leads as occurred during the spontaneous attack. This may be the first reported case of spontaneous hyperventilation producing vasoconstriction, and the patient's previous admissions to the coronary care unit may have been associated with coronary vasospasm induced by hyperventilation. When patients with variant angina report pains in the chest in association with dizziness and breathlessness hyperventilation should be considered to be a possible cause of the symptoms. As coronary vasospasm is increasingly implicated in angina after myocardial infarction the role of hyperventilation should be considered more often.<\/jats:p>","DOI":"10.1136\/bmj.291.6499.851","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T11:00:59Z","timestamp":1238670059000},"page":"851-852","source":"Crossref","is-referenced-by-count":21,"title":["Are coronary artery spasm and progressive damage to the heart associated with the hyperventilation syndrome?"],"prefix":"10.1136","volume":"291","author":[{"given":"L J","family":"Freeman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P G","family":"Nixon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1985,9,28]]},"reference":[{"key":"ref_1","first-page":"245","article-title":"Coronary artery spasm in Prinzmetal angina documentation of coronary angiography","volume":"288","author":"Oliva, P.B.; Potts, D.E.; Pluss, R.G.","year":"1973","unstructured":"Oliva PB, Potts DE, Pluss RG. Coronary artery spasm in Prinzmetal angina documentation of coronary angiography. N EnglJ Med 1973;288:245-51.","journal-title":"N EnglJ Med"},{"key":"ref_2","first-page":"7","article-title":"Breathing exercises in the treatment of hyperventilation and chronic anxiety states","volume-title":"The Chest, Heart and StrokeJournal","volume":"2","author":"Lum, C.L.","year":"1977","unstructured":"Lum CL. Breathing exercises in the treatment of hyperventilation and chronic anxiety states. The Chest, Heart and StrokeJournal 1977;2:7-1 1."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/0002-9149(82)91966-X","article-title":"The hyperventilation test as a method for developing successful therapy in Prinzmetal angina","volume":"49","author":"Girotti, L.A.; Crosatto, JR, Messutti; H.","year":"1982","unstructured":"Girotti LA, Crosatto JR, Messutti H, et al. The hyperventilation test as a method for developing successful therapy in Prinzmetal angina. AmJ7 Cardiol 1982;49:834-41.","journal-title":"AmJ7 Cardiol"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0033-0620(82)90015-9","article-title":"Coronary artery spasm, definition, diagnosis and consequences","volume":"25","author":"Maseri, A.; Chiercha, S.","year":"1982","unstructured":"Maseri A, Chiercha S. Coronary artery spasm, definition, diagnosis and consequences. Progr Cardiovasc Dis 1982;25:169-92.","journal-title":"Progr Cardiovasc Dis"},{"article-title":"Chest pain and the hyperventilation syndrome-some aetiological considerations","author":"LJ, S.Freeman; PGF, Nixon","key":"ref_5","unstructured":"S Freeman LJ, Nixon PGF. Chest pain and the hyperventilation syndrome-some aetiological considerations. Postgrad Med7 (in press)."},{"key":"ref_6","first-page":"1210","article-title":"A curious incident is noted in respect to the young woman who, being disappointed in love, jumped from the Suspension Bridge at Clifton (the highest bridge in England) into the bed of the river Avon, and escaped with very slight injury. Her case, which is of surgical interest, has in this a psychological bearing, for we are informed that, before she left the infirmary, she received three offers of marriage","volume":"i:","year":"1885","unstructured":"A curious incident is noted in respect to the young woman who, being disappointed in love, jumped from the Suspension Bridge at Clifton (the highest bridge in England) into the bed of the river Avon, and escaped with very slight injury. Her case, which is of surgical interest, has in this a psychological bearing, for we are informed that, before she left the infirmary, she received three offers of marriage. (British Medical Joumal 1885;i: 1210.)"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.291.6499.851","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.291.6499.851","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T18:41:15Z","timestamp":1765478475000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.291.6499.851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,9,28]]},"references-count":6,"journal-issue":{"issue":"6499","published-online":{"date-parts":[[1985,9,28]]},"published-print":{"date-parts":[[1985,9,28]]}},"alternative-id":["10.1136\/bmj.291.6499.851"],"URL":"https:\/\/doi.org\/10.1136\/bmj.291.6499.851","relation":{},"ISSN":["0267-0623","1468-5833"],"issn-type":[{"type":"print","value":"0267-0623"},{"type":"electronic","value":"1468-5833"}],"subject":[],"published":{"date-parts":[[1985,9,28]]}}}