{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T21:59:39Z","timestamp":1767650379567,"version":"3.48.0"},"reference-count":28,"publisher":"BMJ","issue":"6501","license":[{"start":{"date-parts":[[1985,10,12]],"date-time":"1985-10-12T00:00:00Z","timestamp":497923200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J (Clin Res Ed)"],"published-print":{"date-parts":[[1985,10,12]]},"abstract":"<jats:p>Continuous ambulatory peritoneal dialysis is a new and increasingly popular method of routine dialysis, but its effect on renal transplantation is uncertain. A non-randomised comparison was made of the outcome of grafting in patients who had been treated before transplantation with continuous ambulatory peritoneal dialysis with that in patients treated with haemodialysis. During the five years, 1979-84, after continuous ambulatory peritoneal dialysis was introduced to Newcastle upon Tyne 220 patients have received transplants after either continuous ambulatory peritoneal dialysis (61 patients) or haemodialysis (159 patients). During follow up no significant differences occurred in survival of patients or grafts between the two treatment groups. One year after transplantation the percentages of survivors who had received continuous ambulatory peritoneal dialysis and haemodialysis were 88% and 91% respectively, and overall graft survival was 66% and 72%, respectively. A multiple regression model was used to allow for differences among patients--for example, duration of dialysis and number of preoperative transfusions--on the survival of grafts. When only first cadaver grafts were considered (in 152 patients) graft survival (non-immunological failures excluded) was not significantly different between the patients treated with continuous ambulatory peritoneal dialysis and haemodialysis. Continuous ambulatory peritoneal dialysis is not a risk factor in renal transplantation, and its continued use in treatment of potential renal graft recipients is recommended.<\/jats:p>","DOI":"10.1136\/bmj.291.6501.1001","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T11:00:59Z","timestamp":1238670059000},"page":"1001-1004","source":"Crossref","is-referenced-by-count":20,"title":["Continuous ambulatory peritoneal dialysis and renal transplantation: a five year experience."],"prefix":"10.1136","volume":"291","author":[{"given":"P K","family":"Donnelly","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T W","family":"Lennard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Proud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R M","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Henderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Fletcher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W","family":"Elliott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M K","family":"Ward","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Wilkinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1985,10,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.0954-6820.1944.tb03951.x","article-title":"The artificial kidney: a dialyser with a great area","volume":"117","author":"Kolff, W.J.; Berk, H.T.J.; Welle, M.; van Ley, A.J.W.; van Dijk, E.C.; van Noordwijk, J.","year":"1944","unstructured":"Kolff WJ, Berk HTJ, Welle M, van Ley AJW, van Dijk EC, van Noordwijk J. The artificial kidney: a dialyser with a great area. Acta Med Scand 1944;117:121.","journal-title":"Acta Med Scand"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1159\/000182504","article-title":"Continuous ambulatory peritoneal dialysis-1981","volume":"30","author":"Oreopoulos, D.G.; Khanna, R.; Williams, P.; Vas, S.I.","year":"1982","unstructured":"Oreopoulos DG, Khanna R, Williams P, Vas SI. Continuous ambulatory peritoneal dialysis-1981. Nephron 1982;30:293-303.","journal-title":"Nephron"},{"key":"ref_3","first-page":"5","article-title":"Combined report on regular dialysis","volume-title":"and transplantation in Europe. Proc Eur Dial Transplant Assoc","volume":"20","author":"Wing, A.J.; Broyer, M.; Brunner, F.P.; Brynger, H.","year":"1983","unstructured":"Wing AJ, Broyer M, Brunner FP, Brynger H, et al. Combined report on regular dialysis and transplantation in Europe. Proc Eur Dial Transplant Assoc 1983; 20:5-78."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1172\/JCI103085","article-title":"Experiences with renal transplantation in the human-report of nine cases","volume":"34","author":"Hume, D.M.; Mervill, J.P.; Miller, B.F.; Thorn, G.W.","year":"1955","unstructured":"Hume DM, Mervill JP, Miller BF, Thorn GW. Experiences with renal transplantation in the human-report of nine cases. J Clin Invest 1955;34:327.","journal-title":"J Clin Invest"},{"key":"ref_5","first-page":"229","article-title":"Dominant effect of transfusion on kidney graft survival","volume":"24","author":"Opelz, G.; Terasaki, P.I.","year":"1980","unstructured":"Opelz G, Terasaki PI. Dominant effect of transfusion on kidney graft survival. Transplantation 1980;24:229-35.","journal-title":"Transplantation"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1002\/bjs.1800711125","article-title":"CAPD-a risk factor in clinical renal transplantation ?","volume":"71","author":"Guillou, P.J.; Will, E.J.; Davison, A.M.; Giles, G.R.","year":"1984","unstructured":"Guillou PJ, Will EJ, Davison AM, Giles GR. CAPD-a risk factor in clinical renal transplantation ? BrJ Surg 1984;71:878-80.","journal-title":"BrJ Surg"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1136\/bmj.284.6318.779","article-title":"Superiority of B locus matching over other HLA matching in renal graft survival","volume":"284","author":"Dewar, P.J.; Wilkinson, R.; Elliott, R.W.","year":"1982","unstructured":"Dewar PJ, Wilkinson R, Elliott RW, et al. Superiority of B locus matching over other HLA matching in renal graft survival. Br MedJ 1982;284:779-82.","journal-title":"Br MedJ"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1097\/00007890-197605000-00005","article-title":"Lymphocytotoxic antibody detection and cross matching in renal transplantation","volume":"21","author":"Dewar, P.J.; Murray, S.","year":"1976","unstructured":"Dewar PJ, Murray S. Lymphocytotoxic antibody detection and cross matching in renal transplantation. Transplantation 1976;21:387-90.","journal-title":"Transplantation"},{"key":"ref_9","first-page":"70","article-title":"A transcutaneous prosthesis for prolonged access to the peritoneal cavity","volume":"69","author":"Striker, G.E.; Tenckhoff, A.M.","year":"1971","unstructured":"Striker GE, Tenckhoff AM. A transcutaneous prosthesis for prolonged access to the peritoneal cavity. Surgery 1971;69:70-4.","journal-title":"Surgery"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/bjs.1800710323","article-title":"Surgical aspects of continuous peritoneal dialysis-3 years'","volume":"71","author":"Francis, D.M.A.; Donnelly, P.K.; Veitch, P.S.","year":"1984","unstructured":"Francis DMA, Donnelly PK, Veitch PS, et al. Surgical aspects of continuous peritoneal dialysis-3 years' experience. BrJ Surg 1984;71:225-9.","journal-title":"experience. BrJ Surg"},{"key":"ref_11","first-page":"165","article-title":"Continuous ambulatory peritoneal dialysis: 3 years' experience","volume":"52","author":"Ramos, J.M.; Gokal, R.; Siamopolous, K.; Ward, M.K.; Wilkinson, R.; Kerr, D.N.S.","year":"1983","unstructured":"Ramos JM, Gokal R, Siamopolous K, Ward MK, Wilkinson R, Kerr DNS. Continuous ambulatory peritoneal dialysis: 3 years' experience. Q J Med 1983;52:165-86.","journal-title":"Q J Med"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/0010-468X(72)90019-0","article-title":"A computer program for comparing K samples with right censored-data","volume":"2","author":"Lee, E.; Desu, M.","year":"1972","unstructured":"Lee E, Desu M. A computer program for comparing K samples with right censored-data. Comput Programs Biomed 1972;2: 315-21.","journal-title":"Comput Programs Biomed"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life tables. J7ournal of","volume":"34","author":"Cox, DR","year":"1972","unstructured":"Cox DR. Regression models and life tables. J7ournal of the Royal Statistical Society, Series B 1972;34:187-220.","journal-title":"the Royal Statistical Society, Series B"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1056\/NEJM198408093110603","article-title":"Benefits of HLA-A and HLA-B matching on graft survival and patient outcome after cadavericdonor renal transplantation","volume":"311","author":"Sanfilippo, F.; Vaughn, W.K.; Specs, E.K.; Light, J.A.; le For, W.M.","year":"1984","unstructured":"Sanfilippo F, Vaughn WK, Specs EK, Light JA, le For WM. Benefits of HLA-A and HLA-B matching on graft survival and patient outcome after cadavericdonor renal transplantation. N EnglJ3 Med 1984;311:358-64.","journal-title":"N EnglJ3 Med"},{"key":"ref_15","article-title":"Specific and non-specific immunoregulatory factors and renal allograft survival-a single centre 5","volume-title":"year experience. Transplant Proc (in press)","author":"Donnelly, P.K.; Henderson, R.; Lennard, T.W.J.; Proud, G.; Taylor, R.M.R.","unstructured":"Donnelly PK, Henderson R, Lennard TWJ, Proud G, Taylor RMR. Specific and non-specific immunoregulatory factors and renal allograft survival-a single centre 5 year experience. Transplant Proc (in press)."},{"key":"ref_16","first-page":"1","article-title":"End stage renal failure: coping with the demands","volume":"16","author":"Williams, A.J.; Smith, B.A.; Walls, J.","year":"1984","unstructured":"Williams AJ, Smith BA, Walls J. End stage renal failure: coping with the demands. Health Trends 1984;16:1-3.","journal-title":"Health Trends"},{"key":"ref_17","first-page":"95","article-title":"The effect of maintenance haemodialysis on lymphocyte function I: haemodialysis","volume":"33","author":"Holdsworth, SR, Fitzgerald; MG, Hosking; CS, Atkins; R.C.","year":"1978","unstructured":"Holdsworth SR, Fitzgerald MG, Hosking CS, Atkins RC. The effect of maintenance haemodialysis on lymphocyte function I: haemodialysis. Clin Exp Immunol 1978;33:95-101.","journal-title":"Clin Exp Immunol"},{"key":"ref_18","first-page":"190","article-title":"Haemodialysis, continuous ambulatory peritoneal dialysis","volume-title":"and cellular immunity. Proc Eur Dial Transplant Assoc","volume":"20","author":"Collart, F.; Tielemans, C.; Dratwa, M.; Schandene, L.; Wybran, J.; Dupont, E.","year":"1983","unstructured":"Collart F, Tielemans C, Dratwa M, Schandene L, Wybran J, Dupont E. Haemodialysis, continuous ambulatory peritoneal dialysis and cellular immunity. Proc Eur Dial Transplant Assoc 1983;20:190-4."},{"key":"ref_19","first-page":"338","article-title":"Transfusion-induced anergy: skin test as an index","volume-title":"for pretransplant transfusions. Proc Eur Dial Transplant Assoc","volume":"20","author":"Valderradano, F.; Anaya, F.; Perez-Garcia, R.; Olivas, E.; Vasconez, F.; Jofre, R.","year":"1983","unstructured":"Valderradano F, Anaya F, Perez-Garcia R, Olivas E, Vasconez F, Jofre R. Transfusion-induced anergy: skin test as an index for pretransplant transfusions. Proc Eur Dial Transplant Assoc 1983;20:338-48."},{"key":"ref_20","first-page":"230","article-title":"Improved lymphocyte transformation in vitro of patients on continuous","volume-title":"ambulatory peritoneal dialysis. Proc Eur Dial Transplant Assoc","volume":"20","author":"Langhoff, E.; Ladefoged, J.","year":"1983","unstructured":"Langhoff E, Ladefoged J. Improved lymphocyte transformation in vitro of patients on continuous ambulatory peritoneal dialysis. Proc Eur Dial Transplant Assoc 1983;20:230-5."},{"key":"ref_21","first-page":"372","article-title":"Continuous ambulatory peritoneal dialysis","volume-title":"and cellular immunity. Proc Eur Dial Transplant Assoc","volume":"19","author":"Giagrande, A.; Canta, P.; Limido, A.; de Francero, D.; Malacrida, T.","year":"1982","unstructured":"Giagrande A, Canta P, Limido A, de Francero D, Malacrida T. Continuous ambulatory peritoneal dialysis and cellular immunity. Proc Eur Dial Transplant Assoc 1982;19:372-9."},{"key":"ref_22","first-page":"222","article-title":"Renal transplantation in patients on continuous","volume-title":"ambulatory peritoneal dialysis. Proc Eur Dial Transplant Assoc","volume":"18","author":"Gokal, R.; Ramos, J.M.; Veitch, P.S.","year":"1981","unstructured":"Gokal R, Ramos JM, Veitch PS, et al. Renal transplantation in patients on continuous ambulatory peritoneal dialysis. Proc Eur Dial Transplant Assoc 1981;18:222-7."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1525-1594.1978.tb01626.x","article-title":"Influence of middle molecules on the anemia of uremic patients","volume":"2","author":"Leblr, H.W.; Spiegelhalter, R.; Ulm, A.; Goubeaud, G.; Rawer, P.","year":"1978","unstructured":"Leblr HW, Spiegelhalter R, Ulm A, Goubeaud G, Rawer P. Influence of middle molecules on the anemia of uremic patients. Artif Organs 1978;2:378-81.","journal-title":"Artif Organs"},{"key":"ref_24","first-page":"1046","article-title":"Is anaemia during continuous ambulatory peritoneal dialysis better than during haemodialysis ?","volume":"ii:","author":"Salahudeen, A.K.; Hawkins, T.; Keavey, P.M.; Wilkinson, R.","year":"1983","unstructured":"Salahudeen AK, Hawkins T, Keavey PM, Wilkinson R. Is anaemia during continuous ambulatory peritoneal dialysis better than during haemodialysis ? Lancet 1983;ii:1046-9.","journal-title":"Lancet"},{"key":"ref_25","first-page":"136","article-title":"Blood transfusions and kidney transplants: remaining controversies","volume-title":"Transplant Proc 1981; XIII","author":"Opelz, G.; Mickey, M.R.; Terasaki, P.I.","unstructured":"Opelz G, Mickey MR, Terasaki PI. Blood transfusions and kidney transplants: remaining controversies. Transplant Proc 1981;XIII:136-41."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/S0140-6736(85)91456-4","article-title":"Renal transplantation in the United Kingdom and Ireland-the centre effect","volume":"i:","author":"Taylor, R.M.R.; Ting, A.; Briggs, J.D.","year":"1985","unstructured":"Taylor RMR, Ting A, Briggs JD. Renal transplantation in the United Kingdom and Ireland-the centre effect. Lancet 1985;i:798-803.","journal-title":"Lancet"},{"author":"Accepted 10_July 1985)","key":"ref_27","unstructured":"(Accepted 10_July 1985)"},{"key":"ref_28","unstructured":"An increasing number of patients with end stage renal failure throughout the world have been treated with continuous ambulatory peritoneal dialysis since its introduction in 1976. The 1984 report from the European Dialysis and Transplant Association showed that 5228 patients in Europe had been treated with continuous ambulatory peritoneal dialysis up to December 1983. The United Kingdom accounted for almost a third of this total.' The risk of septic complications secondary to the presence of an","article-title":"An increasing number of patients with end stage renal failure throughout the world have been treated with continuous ambulatory peritoneal dialysis since its introduction in 1976. The 1984 report from the European Dialysis and Transplant Association showed that 5228 patients in Europe had been treated with continuous ambulatory peritoneal dialysis up to December 1983. The United Kingdom accounted for almost a third of this total.' The risk of septic complications secondary to the presence of an"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.291.6501.1001","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.291.6501.1001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T18:50:33Z","timestamp":1765479033000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.291.6501.1001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,10,12]]},"references-count":28,"journal-issue":{"issue":"6501","published-online":{"date-parts":[[1985,10,12]]},"published-print":{"date-parts":[[1985,10,12]]}},"alternative-id":["10.1136\/bmj.291.6501.1001"],"URL":"https:\/\/doi.org\/10.1136\/bmj.291.6501.1001","relation":{},"ISSN":["0267-0623","1468-5833"],"issn-type":[{"type":"print","value":"0267-0623"},{"type":"electronic","value":"1468-5833"}],"subject":[],"published":{"date-parts":[[1985,10,12]]}}}