{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T03:41:57Z","timestamp":1773459717229,"version":"3.50.1"},"reference-count":15,"publisher":"BMJ","issue":"6527","license":[{"start":{"date-parts":[[1986,4,19]],"date-time":"1986-04-19T00:00:00Z","timestamp":514252800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J (Clin Res Ed)"],"published-print":{"date-parts":[[1986,4,19]]},"abstract":"<jats:p>Evidence for hypertension was sought retrospectively in the necropsy records of 37 cadaveric kidney donors who had died of subarachnoid haemorrhage and 41 donors who had died of head injury, cerebral tumour, or (in a few instances) other causes. Mean relative heart weight in the donors with subarachnoid haemorrhage was 0.58 (1 SD = 0.09)% and in the other donors 0.52 (0.09)% (p less than 0.01), a difference unexplained by any factor other than a comparatively higher blood pressure in the donors who had died of subarachnoid haemorrhage. Blood pressure was analysed over 72 months after renal transplantation in 23 recipients with normal or near normal graft function and no evidence of chronic rejection or graft artery stenosis. Twelve patients who had received kidneys from donors with subarachnoid haemorrhage had consistently higher systolic blood pressures (p less than 0.004) and needed more antihypertensive treatment (p less than 0.0004) than the 11 recipients of kidneys from donors who had died of head injury or cerebral tumour. These observations suggest that cadaveric kidneys from donors dying of subarachnoid haemorrhage may induce or sustain hypertension after transplantation.<\/jats:p>","DOI":"10.1136\/bmj.292.6527.1041","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T15:19:55Z","timestamp":1238685595000},"page":"1041-1044","source":"Crossref","is-referenced-by-count":41,"title":["Hypertension in renal allograft recipients may be conveyed by cadaveric kidneys from donors with subarachnoid haemorrhage."],"prefix":"10.1136","volume":"292","author":[{"given":"S","family":"Strandgaard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1986,4,19]]},"reference":[{"key":"ref_1","first-page":"39","article-title":"Severe hypertension and elevated plasma renin activity following transplantation of \"hepatorenal donor\" kidneys into anephric recipients","volume":"54","author":"FD, I.McDonald; LA, Brennan; JG, Turcotte","year":"1973","unstructured":"I McDonald FD, Brennan LA, Turcotte JG. Severe hypertension and elevated plasma renin activity following transplantation of \"hepatorenal donor\" kidneys into anephric recipients. Am J Mcd 1973;54:39-43.","journal-title":"Am J Mcd"},{"key":"ref_2","first-page":"145","article-title":"Late hypertension in renal transplant recipients: possible role of the donor","volume-title":"late primary hypertension. Proc Dial Transplant Formn","volume":"6","author":"Merino, G.E.; Kjellstrand, C.M.; Sammons, R.L.; Najarian, J.S.","year":"1976","unstructured":"Merino GE, Kjellstrand CM, Sammons RL, Najarian JS. Late hypertension in renal transplant recipients: possible role of the donor in late primary hypertension. Proc Dial Transplant Formn 1976;6:145-53."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1042\/cs0470435","article-title":"Blood pressure changes produced by kidney crosstransplantation between spontaneously hypertensive rats and normotensive rats","volume":"47","author":"Bianchi, G.; Fox, U.D.; Francesco, G.F.; a al","year":"1974","unstructured":"Bianchi G, Fox UD, Francesco GF, a al. Blood pressure changes produced by kidney crosstransplantation between spontaneously hypertensive rats and normotensive rats. Clinical Science and MolkcuarMedicine 1974;47:435-48.","journal-title":"Clinical Science and MolkcuarMedicine"},{"key":"ref_4","first-page":"740","article-title":"The cardiac pathology of chronic exogenous obesity","volume":"32","author":"Amad, K.H.; Brennan, J.C.; Alexander, J.K.","year":"1965","unstructured":"Amad KH, Brennan JC, Alexander JK. The cardiac pathology of chronic exogenous obesity. Ciron 1965;32:740-5.","journal-title":"Ciron"},{"issue":"4","key":"ref_5","first-page":"79","article-title":"The relation ofthe weight ofthe heart to the weight ofthe body andoftheweight of the heart to age","volume":"1928","author":"HL, S.Smith","unstructured":"S Smith HL. The relation ofthe weight ofthe heart to the weight ofthe body andoftheweight of the heart to age. AnmHesj 1928;4:79-93.","journal-title":"AnmHesj"},{"key":"ref_6","first-page":"272","article-title":"The pathology of intraaanial arterial aneurysms and their complications","author":"Stebhens, W.E.","year":"1983","unstructured":"Stebhens WE. The pathology of intraaanial arterial aneurysms and their complications. In: Fox JL, ed. Intraaanialaneurysms. New York, Berlin, Heidelberg: Springer-Verlag, 1983:272-357."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1001\/archinte.1978.03630260041014","article-title":"Long term blood pressure changes in renal homotransplantation","volume":"138","author":"Jacquot, C.; Idatte, J.-M.; Bedrossian, J.","year":"1978","unstructured":"Jacquot C, Idatte J-M, Bedrossian J, et al. Long term blood pressure changes in renal homotransplantation. Arch Inen Med 1978;138:233-6.","journal-title":"Arch Inen Med"},{"key":"ref_8","first-page":"1287","article-title":"Hypertension after renal transplantation","volume":"ii:","author":"Bachy, C.; Alexandre, G.P.J.; de Strihou CvanY","year":"1976","unstructured":"Bachy C, Alexandre GPJ, de Strihou CvanY. Hypertension after renal transplantation. BrMedJ 1976;ii: 1287-9.","journal-title":"BrMedJ"},{"key":"ref_9","first-page":"41","article-title":"Prvalence, etiology and treatment ofbte posttransplnthypernsion","volume":"12","author":"de Strihou CvanY; P, Vereerstraeten; M, Wanthier; e al","year":"1983","unstructured":"de Strihou CvanY, Vereerstraeten P, Wanthier M, e al. Prvalence, etiology and treatment ofbte posttransplnthypernsion. AdvNephrol 1983;12:41-60.","journal-title":"AdvNephrol"},{"key":"ref_10","first-page":"73","article-title":"Pose-transpant hypertension and hypertensive encephalopathy in renal allograft recipients","volume":"34","author":"Tejani, A.","year":"1983","unstructured":"Tejani A. Pose-transpant hypertension and hypertensive encephalopathy in renal allograft recipients. Nepron 1983;34:73-8.","journal-title":"Nepron"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1056\/NEJM198310273091702","article-title":"Remission of essential hypertension after renal transplantation","volume":"309","author":"Curtis, J.J.; Luke, R.G.; Dustan, H.P.","year":"1983","unstructured":"Curtis JJ, Luke RG, Dustan HP, et al. Remission of essential hypertension after renal transplantation. NEnglJMed 1983;309:1009-15.","journal-title":"NEnglJMed"},{"key":"ref_12","first-page":"14","article-title":"Hypertension in man with a kidney transplant: role offamilial versus other factors","volume":"41","author":"Guidi, E.; Bianchi, G.; Rivolta, E.; etal","year":"1985","unstructured":"Guidi E, Bianchi G, Rivolta E, etal. Hypertension in man with a kidney transplant: role offamilial versus other factors. Nepkn 1985;41:14-21."},{"key":"ref_13","article-title":"Accepted 4 Februay","year":"1986","unstructured":"(Accepted 4 Februay 1986)"},{"key":"ref_14","article-title":"When measles vaccine was licensed in the United States in 1963 the only live vaccine available was the Enders Edmonston B strain, which produced unacceptable clinical reactions in up to 600\/o of children. With the aim of reducing these reactions standardised measles imunoglobulin was given at the same time in a different site. Though the antibody response was slightly reduced it nevertheless persisted for up to three years.'","year":"1963","unstructured":"When measles vaccine was licensed in the United States in 1963 the only live vaccine available was the Enders Edmonston B strain, which produced unacceptable clinical reactions in up to 600\/o of children. With the aim of reducing these reactions standardised measles imunoglobulin was given at the same time in a different site. Though the antibody response was slightly reduced it nevertheless persisted for up to three years.' Between 1963 and 1965 in the United States some 5 million doses of Edmonston B vaccine were distributed each year with the official recommendation that immunoglobulin should be given simultaneously.","journal-title":"Between; and 1965 in the United States some 5 million doses of Edmonston B vaccine were distributed each year with the official recommendation that immunoglobulin should be given simultaneously"},{"key":"ref_15","article-title":"The antibody response to vaccines given with small doses of immunoglobulin was reported in Britain in 1964.2 The three vaccines were Edmonston B, Edmonston A after 65 further passages, and Edmonston B after 30 passages. The conclusion was that the reactions were mild and the antibody response satisfactory when these vaccines were given with inmunoglobulin but.that the vaccines were not suitable for use alone","unstructured":"The antibody response to vaccines given with small doses of immunoglobulin was reported in Britain in 1964.2 The three vaccines were Edmonston B, Edmonston A after 65 further passages, and Edmonston B after 30 passages. The conclusion was that the reactions were mild and the antibody response satisfactory when these vaccines were given with inmunoglobulin but.that the vaccines were not suitable for use alone."}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.292.6527.1041","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.292.6527.1041","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T12:47:46Z","timestamp":1765543666000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.292.6527.1041"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,4,19]]},"references-count":15,"journal-issue":{"issue":"6527","published-online":{"date-parts":[[1986,4,19]]},"published-print":{"date-parts":[[1986,4,19]]}},"alternative-id":["10.1136\/bmj.292.6527.1041"],"URL":"https:\/\/doi.org\/10.1136\/bmj.292.6527.1041","relation":{},"ISSN":["0267-0623","1468-5833"],"issn-type":[{"value":"0267-0623","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,4,19]]}}}