{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T21:26:48Z","timestamp":1781731608134,"version":"3.54.5"},"reference-count":10,"publisher":"BMJ","issue":"6529","license":[{"start":{"date-parts":[[1986,5,3]],"date-time":"1986-05-03T00:00:00Z","timestamp":515462400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J (Clin Res Ed)"],"published-print":{"date-parts":[[1986,5,3]]},"abstract":"<jats:p>One hundred and three patients with an acute first episode of posterior anal fissure were randomised to receive a three week trial of lignocaine ointment (n = 33) versus hydrocortisone ointment (n = 35) or warm sitz baths combined with an intake of unprocessed bran (n =35). Seven patients were withdrawn owing to failure to adhere to the trial protocol. After one and two weeks of treatment symptomatic relief was significantly better among patients treated with sitz baths and bran than among patients treated with lignocaine ointment or hydrocortisone ointment. After three weeks there was no difference in symptomatic relief among the three groups. Patients treated with lignocaine, however, had significantly fewer healed fissures (60%) than patients treated with hydrocortisone (82.4%) or warm sitz baths and bran (87%). In this study warm sitz baths plus an intake of unprocessed bran came out as the treatment of choice for an acute first episode of posterior anal fissure. This treatment is cheap, has no potential serious side effects, and brings the best and quickest relief of symptoms.<\/jats:p>","DOI":"10.1136\/bmj.292.6529.1167","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T15:19:55Z","timestamp":1238685595000},"page":"1167-1169","source":"Crossref","is-referenced-by-count":122,"title":["Treatment of first episodes of acute anal fissure: prospective randomised study of lignocaine ointment versus hydrocortisone ointment or warm sitz baths plus bran."],"prefix":"10.1136","volume":"292","author":[{"given":"S L","family":"Jensen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1986,5,3]]},"reference":[{"key":"ref_1","article-title":"Essentials of anorectal swgery","author":"Goldberg, S.M.; Gordon, P.H.; Nivatvongs, S.","year":"1980","unstructured":"Goldberg SM, Gordon PH, Nivatvongs S. Essentials of anorectal swgery. Philadelphia, Toronto: Lippincott, 1980."},{"key":"ref_2","first-page":"528","article-title":"Lateral subcutaneous internal sphincterotomy versus anal dilatation in the treatment of fissure in ano in outpatients: a prospective randomised study","volume":"289","author":"Jensen, S.L.; Lund, F.; Nielsen, O.V.; Tange, G.","year":"1984","unstructured":"Jensen SL, Lund F, Nielsen OV, Tange G. Lateral subcutaneous internal sphincterotomy versus anal dilatation in the treatment of fissure in ano in outpatients: a prospective randomised study. BrMedJ 1984;289:528-30.","journal-title":"BrMedJ"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1002\/bjs.1800700312","article-title":"The conservative treatment of fisure-in-ano","volume":"70","author":"Gough, M.J.; Lewis, A.","year":"1983","unstructured":"Gough MJ, Lewis A. The conservative treatment of fisure-in-ano. BrJ Surg 1983;70:175-6.","journal-title":"BrJ Surg"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/bjs.1800640516","article-title":"Fissure-in-ano: the initial management and prognosis","volume":"64","author":"Lock, M.R.; Thomson, J.P.S.","year":"1977","unstructured":"Lock MR, Thomson JPS. Fissure-in-ano: the initial management and prognosis. Br J Surg 1977;64:355-8.","journal-title":"Br J Surg"},{"key":"ref_5","first-page":"312","article-title":"Treatment of fissure in ano","volume":"28","author":"Fries, B.; Rietz, K.A.","year":"1964","unstructured":"Fries B, Rietz KA. Treatment of fissure in ano. Acta ChirScand 1964;l28:312-5.","journal-title":"Acta ChirScand"},{"key":"ref_6","article-title":"Surgery ofanus, rectum, and colon","author":"Goligher, J.C.","year":"1980","unstructured":"Goligher JC. Surgery ofanus, rectum, and colon. 4th ed. London: Balliere, Tindall, 1980.","edition":"4th ed"},{"key":"ref_7","first-page":"215","article-title":"Painful anal ulceration in homosexual men","volume":"71","author":"McMillan, A.; Smith, I.W.","year":"1984","unstructured":"McMillan A, Smith IW. Painful anal ulceration in homosexual men. BrJSurg 1984;71:215-6.","journal-title":"BrJSurg"},{"key":"ref_8","article-title":"Principles and practice ofrectal surgery","author":"Gabriel, W.B.","year":"1948","unstructured":"Gabriel WB. Principles and practice ofrectal surgery. 4th ed. London: Lewis, 1948.","edition":"4th ed"},{"key":"ref_9","first-page":"988","article-title":"Bran tablets and diverticulardisease","volume":"i:","author":"Tayler, I.; Duthie, H.L.","year":"1976","unstructured":"Tayler I, Duthie HL. Bran tablets and diverticulardisease. BrMedJ 1976;i:988-90.","journal-title":"BrMedJ"},{"key":"ref_10","year":"1986","unstructured":"(Accepted 27 March 1986)"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.292.6529.1167","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.292.6529.1167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T12:56:28Z","timestamp":1765544188000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.292.6529.1167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,5,3]]},"references-count":10,"journal-issue":{"issue":"6529","published-online":{"date-parts":[[1986,5,3]]},"published-print":{"date-parts":[[1986,5,3]]}},"alternative-id":["10.1136\/bmj.292.6529.1167"],"URL":"https:\/\/doi.org\/10.1136\/bmj.292.6529.1167","relation":{},"ISSN":["0267-0623","1468-5833"],"issn-type":[{"value":"0267-0623","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,5,3]]}}}