{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T18:48:18Z","timestamp":1698518898721},"reference-count":13,"publisher":"BMJ","issue":"6627","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ"],"published-print":{"date-parts":[[1988,4,2]]},"DOI":"10.1136\/bmj.296.6627.978","type":"journal-article","created":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T19:19:55Z","timestamp":1238699995000},"page":"978-981","source":"Crossref","is-referenced-by-count":14,"title":["Changes in maternal age distribution and their possible impact on demand for prenatal diagnostic services"],"prefix":"10.1136","volume":"296","author":[{"given":"S.","family":"Holloway","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. J H","family":"Brock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"13","article-title":"Rates of trisomies","volume":"18","author":"Schreinemachers, D.M.; Cross, P.K.; Hook, E.B.","year":"1982","unstructured":"Schreinemachers DM, Cross PK, Hook EB. Rates of trisomies 21, 18, 13 and other chromosome abnormalities in about 20000 prenatal studies compared with estimated rates in livebirths. Hum Genet 1982;61:318-24.","journal-title":"Hum Genet; and other chromosome abnormalities in about 20000 prenatal studies compared with estimated rates in livebirths"},{"key":"ref_2","first-page":"355","article-title":"Prenatal chromosome analysis and its impact","volume":"39","author":"Ferguson-Smith, M.A.","year":"1983","unstructured":"Ferguson-Smith MA. Prenatal chromosome analysis and its impact. BrMedBull 1983;39:355-64.","journal-title":"BrMedBull"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/pd.1970060103","article-title":"Cytogenetic prenatal diagnosis and its relative effectiveness in the Mersey region and north Wales","volume":"6","author":"Walker, S.; Howard, P.J.","year":"1986","unstructured":"Walker S, Howard PJ. Cytogenetic prenatal diagnosis and its relative effectiveness in the Mersey region and north Wales. Prenat Diagn 1986;6:13-24.","journal-title":"Prenat Diagn"},{"key":"ref_4","article-title":"Population Censuses and Surveys. Birth Statistics","volume-title":"and earlier years","author":"Office of","year":"1985","unstructured":"Office of Population Censuses and Surveys. Birth Statistics. London: HMSO, 1985 and earlier years."},{"issue":"261-7","key":"ref_5","first-page":"1","article-title":"Revised estimates and projections of Down's syndrome births in the United States and the effects of prenatal diagnosis utilisation, 1970-2002","volume":"7","author":"Goodwin, B.A.; Huether, C.A.","year":"1987","unstructured":"Goodwin BA, Huether CA. Revised estimates and projections of Down's syndrome births in the United States and the effects of prenatal diagnosis utilisation, 1970-2002. Prenat Diagn 1987;7:261-7 1.","journal-title":"Prenat Diagn"},{"key":"ref_6","article-title":"Population Censuses and Surveys. Population projections, 1983-2023","author":"Office of","year":"1985","unstructured":"Office of Population Censuses and Surveys. Population projections, 1983-2023. London: HMSO, 1985."},{"key":"ref_7","first-page":"115","article-title":"Prenatal diagnosis of chromosome abnormalities","author":"Hsu, L.Y.F.","year":"1986","unstructured":"Hsu LYF. Prenatal diagnosis of chromosome abnormalities. In: Milunsky A, ed. Genetic disorders and thefetus. New York: Plenum, 1986:115-83."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S0140-6736(79)90497-5","article-title":"Planning an amniocentesis service for Down's syndrome","volume":"i:","author":"Alberman, E.; Berry, A.; Polani, P.","year":"1979","unstructured":"Alberman E, Berry A, Polani P. Planning an amniocentesis service for Down's syndrome. Lancet 1979;i:50.","journal-title":"Lancet"},{"key":"ref_9","article-title":"Accepted 3","year":"1987","unstructured":"(Accepted 3 November 1987)"},{"key":"ref_10","article-title":"CBE","author":"Cruickshank, Professor Robert","year":"1899","unstructured":"-Professor Robert Cruickshank, CBE (1899-1974)"},{"key":"ref_11","article-title":"In 1932 I left the bacteriology department of Professor John Cruickshank in Aberdeen University to spend the second year of a scholarship in the Glasgow University department of Professors Robert Muir and Carl Browning. When I took my farewell of John Cruickshank he said: \"You must at once get in touch with my pupil Robert Cruickshank-no relation, but one of the nicest men I know. He will be a brother to you.\" I accepted this advice, began a lifelong friendship, and profited greatly from it","unstructured":"In 1932 I left the bacteriology department of Professor John Cruickshank in Aberdeen University to spend the second year of a scholarship in the Glasgow University department of Professors Robert Muir and Carl Browning. When I took my farewell of John Cruickshank he said: \"You must at once get in touch with my pupil Robert Cruickshank-no relation, but one of the nicest men I know. He will be a brother to you.\" I accepted this advice, began a lifelong friendship, and profited greatly from it."},{"key":"ref_12","article-title":"taught by Cecilia Scott [portrait no 6] who has charge of the baby pneumonia ward and who keeps alive children that nobody else would give a chance of survival.\" This was in 1933-4, still a year before the sulphonamides changed the picture","unstructured":"taught by Cecilia Scott [portrait no 6] who has charge of the baby pneumonia ward and who keeps alive children that nobody else would give a chance of survival.\" This was in 1933-4, still a year before the sulphonamides changed the picture."},{"key":"ref_13","article-title":"Camaraderie at home and abroad In later years Robert always insisted that the staff of his departments should also practise epidemiological microbiology and accept an educational function, especially in respect of food hygiene. Already in his Glasgow days he was reaching out towards epidemiological studies. In 1936 he left Glasgow Royal Infirmary and became director of the London County Council laboratory at the North Western Fever Hospital in London. With a loyal and enthusiastic staff, he became more and more concerned in his investigative work with the mode of spread and control of infections. In 1939-40 he suffered a serious and prolonged chest infection and counted himself lucky to survive. This testing experience greatly influenced him. He showed incredible kindness","unstructured":"Camaraderie at home and abroad In later years Robert always insisted that the staff of his departments should also practise epidemiological microbiology and accept an educational function, especially in respect of food hygiene. Already in his Glasgow days he was reaching out towards epidemiological studies. In 1936 he left Glasgow Royal Infirmary and became director of the London County Council laboratory at the North Western Fever Hospital in London. With a loyal and enthusiastic staff, he became more and more concerned in his investigative work with the mode of spread and control of infections. In 1939-40 he suffered a serious and prolonged chest infection and counted himself lucky to survive. This testing experience greatly influenced him. He showed incredible kindness"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.296.6627.978","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T22:51:29Z","timestamp":1601074289000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.296.6627.978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,4,2]]},"references-count":13,"journal-issue":{"issue":"6627","published-print":{"date-parts":[[1988,4,2]]}},"URL":"https:\/\/doi.org\/10.1136\/bmj.296.6627.978","relation":{},"ISSN":["0959-8138","1468-5833"],"issn-type":[{"value":"0959-8138","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,4,2]]}}}