{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T21:57:21Z","timestamp":1793051841787,"version":"4.5.0"},"reference-count":0,"publisher":"BMJ","issue":"5821","license":[{"start":{"date-parts":[[1972,7,29]],"date-time":"1972-07-29T00:00:00Z","timestamp":81216000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Br Med J"],"published-print":{"date-parts":[[1972,7,29]]},"abstract":"<jats:p>Synthetic luteinizing hormone\/follicle stimulating hormone-releasing hormone (LH\/FSH-RH) (50 \u03bcg) was given intravenously to six women with oligomenorrhoea and to four women with secondary amenorrhoea. Peripheral venous blood was withdrawn at regular intervals over a 24-hour period. The concentrations of LH, FSH, and oestradiol-17\u03b2 were determined by radioimmunoassay. In all subjects there was a variable rise in LH (3-16 times the mean basal level): in six a small rise in FSH (two to three times the mean basal level) and in seven a twofold to threefold rise in oestradiol three to eight hours after the rise in gonadotrophins.<\/jats:p>","DOI":"10.1136\/bmj.3.5821.271","type":"journal-article","created":{"date-parts":[[2009,4,8]],"date-time":"2009-04-08T15:21:07Z","timestamp":1239204067000},"page":"271-273","source":"Crossref","is-referenced-by-count":9,"title":["Effect of Synthetic Luteinizing Hormone Releasing Hormone (LH FSH-RH) in Women with Menstrual Disorders"],"prefix":"10.1136","volume":"3","author":[{"given":"John","family":"Newton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William P.","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1972,7,29]]},"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.3.5821.271","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.3.5821.271","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T13:49:01Z","timestamp":1765288141000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.3.5821.271"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,7,29]]},"references-count":0,"journal-issue":{"issue":"5821","published-online":{"date-parts":[[1972,7,29]]},"published-print":{"date-parts":[[1972,7,29]]}},"alternative-id":["10.1136\/bmj.3.5821.271"],"URL":"https:\/\/doi.org\/10.1136\/bmj.3.5821.271","relation":{},"ISSN":["0007-1447","1468-5833"],"issn-type":[{"value":"0007-1447","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1972,7,29]]}}}