{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:57:11Z","timestamp":1790233031461,"version":"4.1.0"},"reference-count":12,"publisher":"BMJ","issue":"6918","license":[{"start":{"date-parts":[[1993,12,11]],"date-time":"1993-12-11T00:00:00Z","timestamp":755568000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ"],"published-print":{"date-parts":[[1993,12,11]]},"abstract":"<jats:p>OBJECTIVE--To examine the potential impact of deferral of blood donors at high risk of HIV infection in a west African city where blood is screened for HIV antibodies but no other special measures are taken to protect the blood supply. DESIGN--Cross sectional study. SETTING--National Blood Transfusion Centre and Project RETRO-CI, an international collaborative AIDS research project, Abidjan, C\u00f4te d'Ivoire. SUBJECTS--1257 male first time blood donors. INTERVENTIONS--Blood donors were interviewed about demographic and behavioural characteristics and tested for HIV antibodies by enzyme immunoassay and, if positive, synthetic peptide based tests. MAIN OUTCOME MEASURES--HIV antibody status in relation to presence of behavioural risk factors; calculation of sensitivity, specificity, and predictive values of specific criteria for excluding HIV infected donors. RESULTS--The overall prevalence of HIV infection was 11.4%. The most important risk factors for HIV positivity were prostitute contact and being aged 30-39 years. For identifying seropositive donors individual criteria had sensitivity, specificity, and positive predictive values ranging from 15% to 98%, 38% to 91%, and 17% to 30% respectively. Prostitute contact in the past five years would have excluded 31% of all donors and 73% of HIV infected donors. 27% of those excluded would have been HIV positive. CONCLUSIONS--The widespread assumption that donor deferral is not feasible in sub-Saharan Africa needs reassessment. In Abidjan this approach was well accepted and potentially effective. Donor deferral requires evaluation as a strategy for improving blood safety in resource poor areas with high rates of HIV infection.<\/jats:p>","DOI":"10.1136\/bmj.307.6918.1517","type":"journal-article","created":{"date-parts":[[2009,3,30]],"date-time":"2009-03-30T08:16:37Z","timestamp":1238400997000},"page":"1517-1519","source":"Crossref","is-referenced-by-count":38,"title":["Excluding blood donors at high risk of HIV infection in a west African city."],"prefix":"10.1136","volume":"307","author":[{"given":"R","family":"Schutz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Savarit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J C","family":"Kadjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Batter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Kone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"La Ruche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Bondurand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K M","family":"De Cock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1993,12,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1046\/j.1537-2995.1991.31892023494.x","article-title":"HIV Blood Donor Study Group. 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AIDS 1991;5:S163-8.","journal-title":"AIDS"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1097\/00002030-199211000-00026","article-title":"Difficulties associated with providing an HIV-free blood supply in tropical Africa","volume":"6","author":"Ryder, R.W.","year":"1992","unstructured":"Ryder RW. Difficulties associated with providing an HIV-free blood supply in tropical Africa. AIDS 1992;6:1395-7.","journal-title":"AIDS"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1136\/bmj.305.6852.498","article-title":"Risk of HIV infection from transfusion with blood negative for HIV antibody in a west African city","volume":"305","author":"Savarit, D.; De Cock, K.M.; Schutz, R.; Konate, S.; Lackritz, E.; Bondurand, A.","year":"1992","unstructured":"Savarit D, De Cock KM, Schutz R, Konate S, Lackritz E, Bondurand A. Risk of HIV infection from transfusion with blood negative for HIV antibody in a west African city. 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