{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T13:58:03Z","timestamp":1778680683214,"version":"3.51.4"},"reference-count":30,"publisher":"BMJ","issue":"6924","license":[{"start":{"date-parts":[[1994,1,29]],"date-time":"1994-01-29T00:00:00Z","timestamp":759801600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ"],"accepted":{"date-parts":[[1993,10,28]]},"published-print":{"date-parts":[[1994,1,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective<\/jats:bold>\n                    : To describe blood pressure in twins during infancy.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design<\/jats:bold>\n                    : Prospective study of cohort of twins.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Setting<\/jats:bold>\n                    : Teaching hospital in Florida.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Subjects<\/jats:bold>\n                    : 166 viable twin pairs born between July 1976 and December 1989.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Main outcome measures<\/jats:bold>\n                    : Blood pressure and body weight at birth, at 14 days, and at 1, 3, 6, 9, and 12 months.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    : Both systolic and diastolic pressure correlated with body weight throughout infancy (at birth r=0.41, P &lt;0.001 and r=0.42, P&lt;0.001 respectively; at 1 year r=0.23, P&lt;0.001 and r=0.26, P &lt;0.001 respectively). In infants weighing &lt;1500 g at birth mean blood pressure rose from about 45\/25 mm Hg to 101\/55 mm Hg from birth to the age of 1 year, while in infants weighing &gt;3000 g at birth it rose from 63\/39 mm Hg to 100\/61 mm Hg; corresponding mean body weights at 1 year were 7.86 kg and 9.88 kg. Differences in birth weight within pairs of monozygotic twins were negatively correlated with such differences in systolic blood pressure at 1 year (r equal -0.37, P &lt;0.01).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions<\/jats:bold>\n                    : Blood pressure and body weights in twins showed strongly positive but generally declining correlations throughout infancy. Twins of lower birth weight showed a more rapid rate of rise in blood pressure during infancy. At 1 year the catch up in blood pressure exceeded that in body weight. Greater differences in birth weights between monozygotic twins were associated with smaller differences in systolic blood pressure at 1 year, suggesting that intrauterine environmental factors related to birth weight are important in determining blood pressure in infancy.\n                  <\/jats:p>","DOI":"10.1136\/bmj.308.6924.298","type":"journal-article","created":{"date-parts":[[2011,10,27]],"date-time":"2011-10-27T19:19:51Z","timestamp":1319743191000},"page":"298-302","source":"Crossref","is-referenced-by-count":62,"title":["Blood pressure in prospective population based cohort of newborn and infant twins"],"prefix":"10.1136","volume":"308","author":[{"given":"R S","family":"Levine","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C H","family":"Hennekens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M 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