{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T20:41:34Z","timestamp":1775508094097,"version":"3.50.1"},"reference-count":18,"publisher":"BMJ","issue":"7162","license":[{"start":{"date-parts":[[1998,9,26]],"date-time":"1998-09-26T00:00:00Z","timestamp":906768000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ"],"published-print":{"date-parts":[[1998,9,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective:<\/jats:bold>\n                    To analyse sick leave in women at risk of primary hyperparathyroidism before its diagnosis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design:<\/jats:bold>\n                    Case-control study nested within a screened cohort of postmenopausal women. Cases were women with hyperparathyroidism without prior knowledge of their disease and no traditional symptoms or complications. Controls were women from the screened population without hyperparathyroidism.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Setting:<\/jats:bold>\n                    Population based screening within a Swedish community.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Subject:<\/jats:bold>\n                    48 case-control pairs of women aged 55-70 years.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Main outcome measure:<\/jats:bold>\n                    Sick leave during the 5 years before diagnosis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Total duration of sickness benefits was longer in the cases than controls, and this discrepancy included sick leave on full time or half time and for periods of longer than a week. Cases had an increased risk of sick leave more than half of the investigated time compared with controls (odds ratio 12). Doctors' certificates showed that the overrepresented sick leave in the cases related mainly to cardiovascular diseases.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Asymptomatic mild primary hyperparathyroidism in postmenopausal women is accompanied by a previously unrecognised morbidity, which has consequences for clinical management of the disorder and its impact on the health economy.\n                  <\/jats:p>","DOI":"10.1136\/bmj.317.7162.848","type":"journal-article","created":{"date-parts":[[2011,10,27]],"date-time":"2011-10-27T19:54:56Z","timestamp":1319745296000},"page":"848-851","source":"Crossref","is-referenced-by-count":38,"title":["Population based case-control study of sick leave in postmenopausal women before diagnosis of hyperparathyroidism"],"prefix":"10.1136","volume":"317","author":[{"given":"Ewa","family":"Lundgren","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Szabo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sverker","family":"Ljunghall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinhold","family":"Bergstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Holmberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas","family":"Rastad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1998,9,26]]},"reference":[{"key":"2025122308155300000_317.7162.848.1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1365-2362.1988.tb01163.x","article-title":"Prevalence of hypercalcemia in a health survey: a 14 year follow-up study of serum calcium values.","volume":"18","author":"Palm\u00e9r","year":"1988","journal-title":"Eur J Clin Invest"},{"key":"2025122308155300000_317.7162.848.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(97)90357-3"},{"key":"2025122308155300000_317.7162.848.3","first-page":"97","article-title":"Asymptomatic primary hyperparathyroidism discovered by multichannel biochemical screening: clinical course and considerations bearing on the need for surgical intervention.","volume":"6","author":"Parfitt","year":"1991","journal-title":"J Bone Miner Res"},{"key":"2025122308155300000_317.7162.848.4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/jbmr.5650060104","volume":"6","year":"1991","journal-title":"J Bone Miner Res"},{"key":"2025122308155300000_317.7162.848.5","first-page":"111","article-title":"Longitudinal studies of mild primary hyperparathyroidism.","volume":"6","author":"Ljunghall","year":"1991","journal-title":"J Bone Miner Res"},{"key":"2025122308155300000_317.7162.848.6","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(94)90127-9"},{"key":"2025122308155300000_317.7162.848.7","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1148\/radiology.193.2.7972742","article-title":"Population-based mammography screening in Swedish clinical practice: prevalence and incidence screening in Uppsala county.","volume":"193","author":"Thurfjell","year":"1994","journal-title":"Radiology"},{"key":"2025122308155300000_317.7162.848.8","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)91067-V"},{"key":"2025122308155300000_317.7162.848.9","unstructured":"Swedish Insurance Board Sick leave in Sweden 1990: diagnoses and causes of retirements Stockholm: Riksf\u00f6rs\u00e4linngsverbets Publikationsservice 1996(In Swedish.)"},{"key":"2025122308155300000_317.7162.848.10","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1177\/140349489001800202","article-title":"Repeated short-term sick-leave and quality of life.","volume":"18","author":"H\u00f6rnquist","year":"1990","journal-title":"Scand J Soc Med"},{"key":"2025122308155300000_317.7162.848.11","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1177\/140349489101900302","article-title":"The accordance of diagnoses in a computerized sick-leave register with doctor's certificates and medical records.","volume":"19","author":"Ljungdahl","year":"1991","journal-title":"Scand J Soc Med"},{"key":"2025122308155300000_317.7162.848.12","unstructured":"Ljunghall S Joborn C Palm\u00e9r M Rastad J \u00c5kerstr\u00f6m G Primary hyperparathyroidism\u2014the surgically cured patient. In: Kleerekoper M Krane SM , eds. Clinical disorders of bone and mineral metabolism. New York: Mary Ann Liebert 1989."},{"key":"2025122308155300000_317.7162.848.13","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1990.00390190133021"},{"key":"2025122308155300000_317.7162.848.14","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-67-6-1294"},{"key":"2025122308155300000_317.7162.848.15","doi-asserted-by":"publisher","DOI":"10.1007\/BF01658740"},{"key":"2025122308155300000_317.7162.848.16","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0140-6736(87)91906-4","article-title":"Survival and renal function in untreated hypercalcemia. Population-based cohort study with 14 years of follow-up.","volume":"i","author":"Palm\u00e9r","year":"1987","journal-title":"Lancet"},{"key":"2025122308155300000_317.7162.848.17","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(97)90216-6"},{"key":"2025122308155300000_317.7162.848.18","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(97)00270-2"}],"container-title":["BMJ"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bmj.317.7162.848","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmj.317.7162.848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T16:16:01Z","timestamp":1766506561000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bmj.com\/lookup\/doi\/10.1136\/bmj.317.7162.848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,9,26]]},"references-count":18,"journal-issue":{"issue":"7162","published-online":{"date-parts":[[1998,9,26]]},"published-print":{"date-parts":[[1998,9,26]]}},"alternative-id":["10.1136\/bmj.317.7162.848"],"URL":"https:\/\/doi.org\/10.1136\/bmj.317.7162.848","relation":{},"ISSN":["0959-8138","1468-5833"],"issn-type":[{"value":"0959-8138","type":"print"},{"value":"1468-5833","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,9,26]]}}}