{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:30:19Z","timestamp":1792161019880,"version":"4.4.0"},"reference-count":39,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T00:00:00Z","timestamp":1584576000000},"content-version":"unspecified","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011946","name":"Abbott Diabetes Care","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100011946","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open Diab Res Care"],"accepted":{"date-parts":[[2020,2,22]]},"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Observations in real-world settings support and extend findings demonstrated in randomized controlled trials that show flash glucose monitoring improves glycemic control. In this study, Spain-specific relationships between testing frequency and glycemic parameters were investigated under real-world settings.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Research design and methods<\/jats:title>\n                  <jats:p>Deidentified glucose and user scanning data were analyzed and readers were rank ordered into 20 equal sized groups by daily scan frequency. Glucose parameters were calculated for each group: estimated HbA1c, time below range (&lt;70\u2009and \u226454\u2009mg\/dL), within range (70\u2013180\u2009mg\/dL), and above range (&gt;180\u2009mg\/dL). Glycemic variability (GV) metrics were described and data obtained from sensors in Spain and worldwide were compared.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Spanish users (n=22\u2009949) collected 37.1\u2009million glucose scans, 250\u2009million automatically recorded glucose readings, and checked glucose values via a mean of 13 scans\/day. Estimated HbA1c, time below 70\u2009mg\/dL, at or below 54\u2009mg\/dL, above 180\u2009mg\/dL, and GV metrics were significantly lower in the highest compared with lowest scan rate group (39.6 to 3.9 scans\/day). Time-in-range was higher for the highest versus lowest scan rate group at 15.6 vs 11.5\u2009hours\/day, respectively. GV metrics correlated positively with time below 70\u2009mg\/dL, at or below 54\u2009mg\/dL, above 180\u2009mg\/dL, and negatively with time-in-range. The relationship between glucose metrics and scan rate was similar in Spain and worldwide. However, time in hypoglycemia in Spain was higher in the groups with lower scan rates.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>As seen in clinical trials, flash glucose monitoring in real-world settings allows frequent glucose checks. High scan rates are associated with the favorable glycemic markers of increased time-in-range and reduced time in hyperglycemia and hypoglycemia, and GV. The same trends, with unique nuances, are observed in both Spanish and global data.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bmjdrc-2019-001052","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T05:54:33Z","timestamp":1584683673000},"page":"e001052","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":71,"title":["Flash glucose monitoring reduces glycemic variability and hypoglycemia: real-world data from Spain"],"prefix":"10.1136","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0106-0091","authenticated-orcid":false,"given":"Fernando","family":"Gomez-Peralta","sequence":"first","affiliation":[{"name":"Endocrinology and Nutrition Unit, Hospital General de Segovia, Segovia, Castilla y Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3487-2504","authenticated-orcid":false,"given":"Timothy","family":"Dunn","sequence":"additional","affiliation":[{"name":"Research and Development, Abbott Laboratories, Alameda, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7687-0876","authenticated-orcid":false,"given":"Katherine","family":"Landuyt","sequence":"additional","affiliation":[{"name":"Diagnostics Division, Abbott Laboratories, Irving, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9446-8402","authenticated-orcid":false,"given":"Yongjin","family":"Xu","sequence":"additional","affiliation":[{"name":"Research and Development, Abbott Laboratories, Alameda, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0191-4504","authenticated-orcid":false,"given":"Juan Francisco","family":"Merino-Torres","sequence":"additional","affiliation":[{"name":"Department of Medicine, Universitat de Val\u00e8ncia Facultat de Medicina i Odontologia, Valencia, Comunitat Valenciana, Spain"},{"name":"Endocrinology and Nutrition Department, Hospital Universitari i Politecnic La Fe, Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,3,19]]},"reference":[{"key":"2025073111385305000_8.1.e001052.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199309303291401"},{"key":"2025073111385305000_8.1.e001052.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa052187"},{"key":"2025073111385305000_8.1.e001052.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199306103282306"},{"key":"2025073111385305000_8.1.e001052.4","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.321.7258.405"},{"key":"2025073111385305000_8.1.e001052.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0802987"},{"key":"2025073111385305000_8.1.e001052.6","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-s220"},{"key":"2025073111385305000_8.1.e001052.7","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-1915"},{"key":"2025073111385305000_8.1.e001052.8","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-0916"},{"key":"2025073111385305000_8.1.e001052.9","doi-asserted-by":"crossref","DOI":"10.1136\/bmjdrc-2015-000094","article-title":"An observational study of patient characteristics and mortality following hypoglycemia in the community","volume":"3","author":"Elwen","year":"2015","journal-title":"BMJ Open Diabetes Res Care"},{"key":"2025073111385305000_8.1.e001052.10","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-0920"},{"key":"2025073111385305000_8.1.e001052.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2010.00650.x"},{"key":"2025073111385305000_8.1.e001052.12","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-2643"},{"key":"2025073111385305000_8.1.e001052.13","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-S006"},{"key":"2025073111385305000_8.1.e001052.14","doi-asserted-by":"publisher","DOI":"10.2337\/diaclin.20.1.45"},{"key":"2025073111385305000_8.1.e001052.15","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-012-2534-0"},{"key":"2025073111385305000_8.1.e001052.16","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-2441"},{"key":"2025073111385305000_8.1.e001052.17","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-1770"},{"key":"2025073111385305000_8.1.e001052.18","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-924152"},{"key":"2025073111385305000_8.1.e001052.19","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3111\/13696998.2013.873722","article-title":"Frequency of blood glucose testing among insulin-treated diabetes mellitus patients in the United Kingdom","volume":"17","author":"Lee","year":"2014","journal-title":"J Med Econ"},{"key":"2025073111385305000_8.1.e001052.20","unstructured":"Glooko+Diasend . 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Efectividad, seguridad y coste-efectividad del sistema flash de monitorizaci\u00f3n de glucosa en l\u00edquido intersticial (FreeStyle Libre\u00ae) para la Diabetes Mellitus tipo 1 y 2. Ministerio de Sanidad, Servicios Sociales e Igualdad. Servicio de Evaluaci\u00f3n del Servicio Canario de la Salud 2016. Informes de Evaluaci\u00f3n de Tecnolog\u00edas Sanitarias."}],"container-title":["BMJ Open Diabetes Research &amp; Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjdrc-2019-001052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T18:40:02Z","timestamp":1753987202000},"score":1,"resource":{"primary":{"URL":"https:\/\/drc.bmj.com\/lookup\/doi\/10.1136\/bmjdrc-2019-001052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":39,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,3,19]]},"published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1136\/bmjdrc-2019-001052"],"URL":"https:\/\/doi.org\/10.1136\/bmjdrc-2019-001052","relation":{},"ISSN":["2052-4897"],"issn-type":[{"value":"2052-4897","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3]]}}}