{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T11:18:33Z","timestamp":1783682313805,"version":"3.55.0"},"reference-count":47,"publisher":"BMJ","issue":"4","license":[{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"unspecified","delay-in-days":9,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009708","name":"Novo Nordisk Foundation","doi-asserted-by":"crossref","award":["NNF24SA0096286"],"award-info":[{"award-number":["NNF24SA0096286"]}],"id":[{"id":"10.13039\/501100009708","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open Diab Res Care"],"accepted":{"date-parts":[[2026,6,28]]},"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Population-based surveillance is essential for quantifying the burden of diabetes and monitoring temporal changes. In Denmark, nationwide health registers enable long-term surveillance of type 1 diabetes (T1D) and type 2 diabetes (T2D). We aimed to estimate trends in prevalence, incidence, mortality and years of life lost to diabetes in Denmark from 1996 to 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Research design and methods<\/jats:title>\n                    <jats:p>We conducted a nationwide register-based cohort study from 1996 to 2024. We used an updated national diabetes register integrating hospital, prescription, clinical, and laboratory data to identify diabetes type and date of onset. Prevalence was estimated annually using a binomial model. Incidence, mortality and standardized mortality ratios (SMR) were analyzed using age-period-cohort models. Analyses were stratified by sex and diabetes type. A multistate model was used to assess the lifetime risk and years of life lost to diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>As of January 1, 2025, a total of 366\u2009174 individuals (6.1% of the population) had diabetes identified through national healthcare registers; of these, 8.2% had T1D and 91.8% had T2D. Since 1996, diabetes prevalence more than tripled, largely driven by an overall annual increase in T2D of ~4.1%. T1D prevalence remained stable, with increases in individuals aged &lt;40 years and decreases in older age groups. From 1996 to 2024, a total of 567\u2009510 incident diabetes cases were recorded, of which 4.6% were T1D. T1D incidence declined on average by 1.1% annually, with increasing rates at younger ages and declining rates at older ages. T2D incidence showed a non-linear pattern, with a decline from 2010 to 2015 followed by an increase in recent years, resulting in an overall upward trend from 1996 to 2024. Men had higher T2D incidence than women across age and calendar years. Mortality declined for T1D after 2008 and for T2D until 2012, then stabilized. SMRs decreased for T1D after 2008 but increased for T2D, converging by 2025.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In Denmark, diabetes prevalence and incidence increased markedly since 1996, largely driven by T2D. Although mortality declined, particularly for T1D, excess mortality remains, emphasizing the need for continued surveillance and prevention efforts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjdrc-2026-006129","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T11:10:20Z","timestamp":1783681820000},"page":"e006129","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence, incidence, mortality, and years of life lost to diabetes from 1996 to 2024 in Denmark"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4989-2084","authenticated-orcid":false,"given":"Rasmus","family":"Wibaek","sequence":"first","affiliation":[{"name":"Steno Diabetes Center Copenhagen, Herlev, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanja","family":"Kosjerina","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Copenhagen, Herlev, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stine","family":"Byberg","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Copenhagen, Herlev, Denmark"},{"name":"Steno Diabetes Center Greenland, Nuuk, Greenland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hjalte S","family":"Mikkelsen","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Copenhagen, Herlev, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina J-Y","family":"Lee","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Copenhagen, Herlev, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1531-4294","authenticated-orcid":false,"given":"Peter","family":"Rossing","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Copenhagen, Herlev, Denmark"},{"name":"Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bendix","family":"Carstensen","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Copenhagen, Herlev, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pernille Falberg","family":"R\u00f8nn","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Copenhagen, Herlev, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,7,10]]},"reference":[{"key":"2026071004100932000_14.4.e006129.1","doi-asserted-by":"crossref","first-page":"S325","DOI":"10.2105\/AJPH.2012.300811","article-title":"Integrating clinical practice and public health surveillance using electronic medical record systems","volume":"102 Suppl 3","author":"Klompas","year":"2012","journal-title":"Am J Public Health"},{"key":"2026071004100932000_14.4.e006129.2","article-title":"Applications of electronic health information in public health: uses, opportunities & barriers","volume":"1","author":"Tomines","year":"2013","journal-title":"EGEMS (Wash DC)"},{"key":"2026071004100932000_14.4.e006129.3","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1093\/jamia\/ocaa186","article-title":"Electronic health record-based disease surveillance systems: A systematic literature review on challenges and solutions","volume":"27","author":"Aliabadi","year":"2020","journal-title":"J Am Med Inform Assoc"},{"key":"2026071004100932000_14.4.e006129.4","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S2213-8587(20)30402-2","article-title":"Trends in the incidence of diagnosed diabetes: a multicountry analysis of aggregate data from 22 million diagnoses in high-income and middle-income settings","volume":"9","author":"Magliano","year":"2021","journal-title":"Lancet Diabetes Endocrinol"},{"key":"2026071004100932000_14.4.e006129.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-008-1156-z"},{"key":"2026071004100932000_14.4.e006129.6","doi-asserted-by":"crossref","DOI":"10.1136\/bmjdrc-2019-001071","article-title":"Prevalence, incidence and mortality of type 1 and type 2 diabetes in Denmark 1996-2016","volume":"8","author":"Carstensen","year":"2020","journal-title":"BMJ Open Diabetes Res Care"},{"key":"2026071004100932000_14.4.e006129.7","doi-asserted-by":"crossref","DOI":"10.1136\/bmjdrc-2019-001065","article-title":"Lifetime risk and years lost to type 1 and type 2 diabetes in Denmark, 1996-2016","volume":"9","author":"Carstensen","year":"2021","journal-title":"BMJ Open Diabetes Res Care"},{"key":"2026071004100932000_14.4.e006129.8","unstructured":"Novo nordisk foundation. 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