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Currently available LASV diagnostic methods are difficult to operationalise in low-resource health centres and may be less sensitive to detecting all known or emerging LASV strains. To prioritise diagnostic development for LASV, we assessed the diagnostic applications for case detection, clinical management, surveillance, outbreak response, and therapeutic and vaccine development at various healthcare levels. Diagnostic development should prioritise point-of-care and near-patient diagnostics, especially those with the ability to detect all lineages of LASV, as they would allow for rapid detection in resource-limited health facilities closer to the patient.<\/jats:p>","DOI":"10.1136\/bmjgh-2018-001119","type":"journal-article","created":{"date-parts":[[2019,2,8]],"date-time":"2019-02-08T05:40:25Z","timestamp":1549604425000},"page":"e001119","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["Diagnostic applications for Lassa fever in limited-resource settings"],"prefix":"10.1136","volume":"4","author":[{"given":"Devy M","family":"Emperador","sequence":"first","affiliation":[{"name":"Foundation for Innovative New Diagnostics (FIND), Emerging Threats Programme, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solomon A","family":"Yimer","sequence":"additional","affiliation":[{"name":"Department of Vaccine Science, Coalition for Epidemic Preparedness Innovation (CEPI), Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura T","family":"Mazzola","sequence":"additional","affiliation":[{"name":"Foundation for Innovative New Diagnostics (FIND), Emerging Threats Programme, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunnstein","family":"Norheim","sequence":"additional","affiliation":[{"name":"Department of Vaccine Science, Coalition for Epidemic Preparedness Innovation (CEPI), Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra","family":"Kelly-Cirino","sequence":"additional","affiliation":[{"name":"Foundation for Innovative New Diagnostics (FIND), Emerging Threats Programme, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,2,7]]},"reference":[{"key":"2025073013023588000_4.Suppl_2.e001119.1","doi-asserted-by":"crossref","unstructured":"Mazzola LT , Kelly-Cirino C . 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