{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T23:17:14Z","timestamp":1784157434366,"version":"3.55.0"},"reference-count":60,"publisher":"BMJ","issue":"Suppl 8","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"unspecified","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100032626","name":"UNITAID","doi-asserted-by":"crossref","award":["2019-34-AIRE"],"award-info":[{"award-number":["2019-34-AIRE"]}],"id":[{"id":"10.13039\/100032626","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Glob Health"],"accepted":{"date-parts":[[2025,10,30]]},"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Integrated Management of Childhood Illness (IMCI) guidelines are symptom-based algorithms used to identify critically ill children under five in primary health centres (PHC) in resource-limited countries. Hypoxaemia, a life-threatening event, is clinically underdiagnosed. The Am\u00e9lioration de l'Identification des d\u00e9tresses Respiratoires de l'Enfant\/Improving Identification of Respiratory Distress in Children (AIRE) project implemented the routine use of pulse oximetry (PO) within IMCI consultations to improve the diagnosis and management of severe hypoxaemia (pulse blood oxygen saturation &lt;90%) at PHC level in Burkina Faso, Guinea, Mali and Niger. In this context, we measured the prevalence of severe cases and their associated social and structural factors among outpatients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In 16 AIRE research PHC (4\/country), all the children under five attending IMCI consultations, except those aged 2\u201359 months classified as simple case without cough or breathing difficulties, were eligible for the use of PO and enrolled in a cross-sectional study with parental consent. Severe IMCI+PO cases were IMCI severe cases or those with severe hypoxaemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From June 2021 to June 2022, 968 neonates (0\u201359\u2009days) and 14\u2009868 children (2\u201359 months) were included. Prevalence of severe IMCI+PO cases was heterogeneous between countries: 5.0% in Burkina Faso, 6.1% in Niger, 18.9% in Mali and 44.6% in Guinea. Among neonates, 21.9% (95% CI 19.3 to 24.6) were severe cases versus 12.0% (95% CI 11.4 to 12.5) in older children, of which 3.3% versus 0.8%, respectively (p&lt;0.001), had severe hypoxaemia. The adjusted social and structural factors associated with disease severity common to all four countries were as follows: age &lt;2 months or &gt;2 years, IMCI consultation delay &gt;2\u2009days, home to PHC travel time &gt;30\u2009min.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The prevalence of seriously ill children under five, including severe hypoxaemia, was high in PHC, particularly in neonates. The high between-country heterogeneity may be explained by differences in case definitions (Guinea) and structural factors (accessibility). Improving early access to primary care could be an actionable lever to improve the health of West African children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjgh-2024-017299","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T11:20:14Z","timestamp":1764242414000},"page":"e017299","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Prevalence and factors associated with severe illness in West African children under 5 years of age detected with routine pulse oximetry in primary care"],"prefix":"10.1136","volume":"10","author":[{"given":"Kessi\u00e8d\u00e9 Gildas Boris","family":"Hedible","sequence":"first","affiliation":[{"name":"Toulouse University, Inserm, Centre for Epidemiology and Research in Population Health (CERPOP), Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoul 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