{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T03:38:50Z","timestamp":1793158730489,"version":"4.5.0"},"reference-count":60,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T00:00:00Z","timestamp":1723420800000},"content-version":"unspecified","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["bmjonc"],"accepted":{"date-parts":[[2024,7,22]]},"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>The objective of this study is to present a cross-sectional analysis of cancer burden in the South Asian Association for Regional Cooperation (SAARC) region and explain unique characteristics of its cancer burden as compared with the rest of the world.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and analysis<\/jats:title>\n                  <jats:p>Using publicly available data from the Global Cancer Observatory (GCO) and the World Bank, we collected cancer statistics and population statistics for Afghanistan, Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri Lanka from 2017 to 2022.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The number of newly diagnosed cases in the region was 1 846 963, representing 9.3% of the incidence worldwide. As defined by the GCO, the crude incidence rate (CIR) (per 100 000) of cancer in SAARC was 97.3 compared with the worldwide rate of 235.5. The crude mortality rate (per 100 000) in SAARC was 63.4, compared with 123.6 globally. However, the mortality to incidence ratio (MIR) (per 100 000) was 0.65, compared with 0.49 globally.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Our research highlights SAARC\u2019s unique cancer landscape with low incidence (CIR) and mortality (CMR) but elevated MIR compared with global figures. These findings underscore the need for a united, contextually relevant approach to addressing the burden of cancer in SAARC. In particular, investment in collaborative, tailored cancer care programmes will build the SAARC region\u2019s capacity to address the growing cancer challenge.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bmjonc-2024-000466","type":"journal-article","created":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T08:00:31Z","timestamp":1723449631000},"page":"e000466","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":17,"title":["Cancer burden across the South Asian Association for Regional Cooperation in 2022"],"prefix":"10.1136","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0012-1991","authenticated-orcid":false,"given":"Urvish","family":"Jain","sequence":"first","affiliation":[{"name":"School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faraan","family":"Rahim","sequence":"additional","affiliation":[{"name":"Global Health Institute, Duke University, Durham, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2648-4894","authenticated-orcid":false,"given":"Bhav","family":"Jain","sequence":"additional","affiliation":[{"name":"School of Medicine, Stanford University, Stanford, California, USA"},{"name":"Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhinav","family":"Komanduri","sequence":"additional","affiliation":[{"name":"Department of Health Promotion and Disease Prevention, University of Southern California, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya","family":"Arkalgud","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron John","family":"Sabet","sequence":"additional","affiliation":[{"name":"Georgetown University Medical Center, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Hammond","sequence":"additional","affiliation":[{"name":"Department of Biology, Harvard University, Cambridge, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phub","family":"Tshering","sequence":"additional","affiliation":[{"name":"Department of ENT and Head Neck Surgery, Jigme Dorji Wangchuk National Referral Hospital, Thimphu, Bhutan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0882-2960","authenticated-orcid":false,"given":"Tej A","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Healthcare Management & Policy, University of Pennsylvania, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8093-1531","authenticated-orcid":false,"given":"Bhawna","family":"Sirohi","sequence":"additional","affiliation":[{"name":"Department of Oncology, Balco Medical Centre, Naya Raipur, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pankaj","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Business Technology and Service Delivery, Highmark Health, Pittsburgh, Pennsylvania, USA"},{"name":"Department of Health Services Administration, Indiana University of Pennsylvania, Indiana, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shah Zeb","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Oncology, BINOR Cancer Hospital Bannu, Alamdar, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeeva","family":"Gunasekera","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Clinical Oncology, National Cancer Institute Sri Lanka, Maharagama, Sri Lanka"},{"name":"Department of Pediatric Oncology, Lanka Cancer Research Group, Maharagama, Sri Lanka"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramila","family":"Shilpakar","sequence":"additional","affiliation":[{"name":"Department of Oncology, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zabihullah","family":"Stanikzai","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology, Jamhuriyat Hospital, Kabul, Afghanistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arman Reza","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Department of Oncology, Evercare Hospital, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishwant","family":"Swami","sequence":"additional","affiliation":[{"name":"Harvard T.H. 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