{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:26:11Z","timestamp":1765758371455,"version":"build-2065373602"},"reference-count":29,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2014,5,16]]},"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>This study aims to assess the feasibility of acupuncture as an add-on intervention for patients with non-emergent acute musculoskeletal pain and primary headache in an emergency department (ED) setting.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and analysis<\/jats:title>\n                  <jats:p>A total of 40 patients who present to the ED and are diagnosed to have acute non-specific neck pain, ankle sprain or primary headache will be recruited by ED physicians. An intravenous or intramuscular injection of analgesics will be provided as the initial standard pain control intervention for all patients. Patients who still have moderate to severe pain after the 30\u2005min of initial standard ED management will be considered eligible. These patients will be allocated in equal proportions to acupuncture plus standard ED management or to standard ED management alone based on computer-generated random numbers concealed in opaque, sealed, sequentially numbered envelopes. A 30\u2005min session of acupuncture treatment with manual and\/or electrical stimulation will be provided by qualified Korean medicine doctors. All patients will receive additional ED management at the ED physician's discretion and based on each patient's response to the allocated intervention. The primary outcome will be pain reduction measured at discharge from the ED by an unblinded assessor. Adverse events in both groups will be documented. Other outcomes will include the patient-reported overall improvement, disability due to neck pain (only for neck-pain patients), the treatment response rate, the use of other healthcare resources and the patients\u2019 perceived effectiveness of the acupuncture treatment. A follow-up telephone interview will be conducted by a blinded assessor 72\u00b112\u2005h after ED discharge.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Ethics and dissemination<\/jats:title>\n                  <jats:p>Written informed consent will be obtained from all participants. The study has been approved by the Institutional Review Boards (IRBs). The results of this study will guide a full-scale randomised trial of acupuncture in an ED context.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Trial registration number<\/jats:title>\n                  <jats:p>ClinicalTrials.gov: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT02013908\">NCT02013908<\/jats:ext-link>.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bmjopen-2014-004994","type":"journal-article","created":{"date-parts":[[2014,6,13]],"date-time":"2014-06-13T20:17:09Z","timestamp":1402690629000},"page":"e004994","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["Acupuncture as analgesia for non-emergent acute non-specific neck pain, ankle sprain and primary headache in an emergency department setting: a protocol for a parallel group, randomised, controlled pilot trial"],"prefix":"10.1136","volume":"4","clinical-trial-number":[{"clinical-trial-number":"nct02013908","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Kun Hyung","family":"Kim","sequence":"first","affiliation":[{"name":"Division of Clinical Medicine, School of Korean Medicine, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Ho","family":"Ryu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, School of Medicine, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maeng Real","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, School of Medicine, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong In","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, School of Medicine, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mun Ki","family":"Min","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, School of Medicine, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Myeon","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, School of Medicine, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu Ri","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Acupuncture & Moxibustion Medicine, Korean Medicine Hospital, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Hee","family":"Noh","sequence":"additional","affiliation":[{"name":"Department of Acupuncture & Moxibustion Medicine, Korean Medicine Hospital, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Joo","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Acupuncture & Moxibustion Medicine, Korean Medicine Hospital, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Jun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Acupuncture & Moxibustion Medicine, Korean Medicine Hospital, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Kyu","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Clinical Medicine, School of Korean Medicine, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Byung Ryul","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Clinical Medicine, School of Korean Medicine, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun Yong","family":"Choi","sequence":"additional","affiliation":[{"name":"Division of Clinical Medicine, School of Korean Medicine, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gi Young","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Clinical Medicine, School of Korean Medicine, Pusan National University, Yangsan, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,6,12]]},"reference":[{"key":"2025101811052057000_4.6.e004994.1","doi-asserted-by":"crossref","unstructured":"Furlan AD van Tulder MW Cherkin DC . 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