{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T08:55:21Z","timestamp":1765875321611,"version":"3.48.0"},"reference-count":31,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2014,5,13]]},"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>To assess the efficacy of herbal medicines as a treatment of cancer cachexia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>We will search the following 13 electronic databases from their inception. MEDLINE (PubMed), the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, Allied and Complementary Medicine Database (AMED), China National Knowledge Infrastructure (CNKI), Wanfang, Journal Integration Platform (VIP) and six Korean Medical Databases (KoreaMed, the Korean Traditional knowledge Portal, OASIS, DBPIA, the Research Information Service System and the Korean Studies Information Service System) without restrictions on time or language. The data will be extracted independently by two authors using predefined criteria. Disagreements will be resolved by discussion between the authors. The risk of bias will be assessed using the Cochrane risk of bias tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Dissemination<\/jats:title>\n                    <jats:p>The review will be published in a journal. The review will also be disseminated electronically and in print. An update of the review will be conducted to inform and guide healthcare practice and policy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>PROSPERO 2013:CRD42013006612.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2014-005016","type":"journal-article","created":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T02:15:16Z","timestamp":1401848116000},"page":"e005016","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Herbal medicines for cancer cachexia: protocol for a systematic review"],"prefix":"10.1136","volume":"4","author":[{"given":"Bongki","family":"Park","sequence":"first","affiliation":[{"name":"Medical Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Hee","family":"Jun","sequence":"additional","affiliation":[{"name":"Medical Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeeyoun","family":"Jung","sequence":"additional","affiliation":[{"name":"Medical Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sooseong","family":"You","sequence":"additional","affiliation":[{"name":"Medical Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0987-9093","authenticated-orcid":false,"given":"Myeong Soo","family":"Lee","sequence":"additional","affiliation":[{"name":"Medical Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,6,3]]},"reference":[{"key":"2025121600503621000_4.6.e005016.1","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.critrevonc.2013.07.015","article-title":"Clinical evaluation and optimal management of cancer cachexia","volume":"88","author":"Tuca","year":"2013","journal-title":"Crit Rev Oncol Hematol"},{"key":"2025121600503621000_4.6.e005016.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2008.06.013"},{"key":"2025121600503621000_4.6.e005016.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2009.12.004"},{"key":"2025121600503621000_4.6.e005016.4","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70218-7"},{"key":"2025121600503621000_4.6.e005016.5","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.ctrv.2013.11.007","article-title":"Towards a simple objective framework for the investigation and treatment of cancer cachexia: the Glasgow Prognostic Score. Cancer treatment reviews","volume":"40","author":"Douglas","year":"2014","journal-title":"Cancer Treat Rev"},{"key":"2025121600503621000_4.6.e005016.6","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00016.2008"},{"key":"2025121600503621000_4.6.e005016.7","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.tem.2012.10.006","article-title":"Cancer cachexia: malignant inflammation, tumorkines, and metabolic mayhem","volume":"24","author":"Tsoli","year":"2013","journal-title":"Trends Endocrinol Metab"},{"key":"2025121600503621000_4.6.e005016.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2012.06.011"},{"key":"2025121600503621000_4.6.e005016.9","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-5002(03)00191-0"},{"key":"2025121600503621000_4.6.e005016.10","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-08-2242"},{"key":"2025121600503621000_4.6.e005016.11","first-page":"CD004310","article-title":"Megestrol acetate for treatment of anorexia-cachexia syndrome","volume":"3","author":"Ruiz Garcia","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"2025121600503621000_4.6.e005016.12","doi-asserted-by":"crossref","first-page":"27","DOI":"10.2147\/CMAR.S7101","article-title":"Optimal management of cancer anorexia-cachexia syndrome","volume":"2","author":"Argiles","year":"2010","journal-title":"Cancer Manag Res"},{"key":"2025121600503621000_4.6.e005016.13","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.biopha.2013.08.005","article-title":"Malnutrition, anorexia and cachexia in cancer patients: a mini-review on pathogenesis and treatment","volume":"67","author":"Nicolini","year":"2013","journal-title":"Biomed Pharmacother"},{"key":"2025121600503621000_4.6.e005016.14","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-006-0198-3"},{"key":"2025121600503621000_4.6.e005016.15","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2007.03-9040"},{"key":"2025121600503621000_4.6.e005016.16","doi-asserted-by":"crossref","first-page":"354","DOI":"10.5142\/jgr.2012.36.4.354","article-title":"Ginseng, the \u2018Immunity Boost\u2019: The Effects of Panax ginseng on Immune System","volume":"36","author":"Kang","year":"2012","journal-title":"J Ginseng Res"},{"key":"2025121600503621000_4.6.e005016.17","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1002\/ptr.4832","article-title":"Panax ginseng in randomised controlled trials: a systematic review","volume":"27","author":"Shergis","year":"2013","journal-title":"Phytother Res"},{"key":"2025121600503621000_4.6.e005016.18","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.appet.2012.11.018","article-title":"Acute effects of a herb extract formulation and inulin fibre on appetite, energy intake and food choice","volume":"62","author":"Harrold","year":"2013","journal-title":"Appetite"},{"key":"2025121600503621000_4.6.e005016.19","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0254-6272(13)60189-2","article-title":"Pharmacological effects of astragaloside IV: a literature review","volume":"33","author":"Ren","year":"2013","journal-title":"J Tradit Chin Med"},{"key":"2025121600503621000_4.6.e005016.20","doi-asserted-by":"publisher","DOI":"10.1177\/1534735409359180"},{"key":"2025121600503621000_4.6.e005016.21","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-010-9276-2"},{"key":"2025121600503621000_4.6.e005016.22","doi-asserted-by":"crossref","first-page":"e70334","DOI":"10.1371\/journal.pone.0070334","article-title":"Targeting cancer-related inflammation: Chinese herbal medicine inhibits epithelial-to-mesenchymal transition in pancreatic cancer","volume":"8","author":"Zhang","year":"2013","journal-title":"PLoS ONE"},{"key":"2025121600503621000_4.6.e005016.23","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3389\/fphar.2011.00010","article-title":"Anti-inflammatory and immunomodulatory effects of paeonia lactiflora pall., a traditional chinese herbal medicine","volume":"2","author":"He","year":"2011","journal-title":"Front Pharmacol"},{"key":"2025121600503621000_4.6.e005016.24","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jep.2011.12.041","article-title":"Fighting fire with fire: poisonous Chinese herbal medicine for cancer therapy","volume":"140","author":"Wang","year":"2012","journal-title":"J Ethnopharmacol"},{"key":"2025121600503621000_4.6.e005016.25","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.jep.2012.07.009","article-title":"Anti-cancer properties of terpenoids isolated from rhizoma curcumae\u2014a review","volume":"143","author":"Lu","year":"2012","journal-title":"J Ethnopharmacol"},{"key":"2025121600503621000_4.6.e005016.26","doi-asserted-by":"crossref","unstructured":"Chen X Guo J Bao J . The anticancer properties of salvia miltiorrhiza bunge (Danshen): a systematic review. Med Res Rev. Published Online First: 7 October 2013. doi: 10.1002\/med.21304","DOI":"10.1002\/med.21304"},{"key":"2025121600503621000_4.6.e005016.27","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/B978-0-12-381272-8.00021-0","article-title":"Rikkunshito as a ghrelin enhancer","volume":"514","author":"Takeda","year":"2012","journal-title":"Methods Enzymol"},{"key":"2025121600503621000_4.6.e005016.28","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3835(00)00496-1"},{"key":"2025121600503621000_4.6.e005016.29","unstructured":"Higgins JPT Altman DG Sterne JAC . Chapter 8: assessing risk of bias in included studies. In: Higgins JPT Green S . eds Cochrane handbook for systematic reviews of interventions version 5.1.0 (updated March 2011). The Cochrane Collaboration. http:\/\/www.cochrane-handbook.org , 2011."},{"key":"2025121600503621000_4.6.e005016.30","unstructured":"Deeks JJ Higgins JPT Altman DG . Chapter 9: analysing data and undertaking meta-analyses. In: Higgins JPT Green S . eds Cochrane handbook for systematic reviews of interventions version 5.1.0 (updated March 2011). The Cochrane Collaboration. 2011. http:\/\/www.cochrane-handbook.org"},{"key":"2025121600503621000_4.6.e005016.31","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2014-005016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T08:50:53Z","timestamp":1765875053000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2014-005016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":31,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2014,6,3]]},"published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1136\/bmjopen-2014-005016"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2014-005016","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"type":"print","value":"2044-6055"},{"type":"electronic","value":"2044-6055"}],"subject":[],"published":{"date-parts":[[2014,6]]}}}