{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:04:55Z","timestamp":1790665495977,"version":"4.1.0"},"reference-count":17,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2014,8,1]]},"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To detect\n                      <jats:italic>Mycoplasma genitalium<\/jats:italic>\n                      in urine samples of infertile men and men without any signs of infection in order to investigate whether\n                      <jats:italic>M. genitalium<\/jats:italic>\n                      and other genital mycoplasmas (\n                      <jats:italic>Mycoplasma hominis<\/jats:italic>\n                      and\n                      <jats:italic>Ureaplasma<\/jats:italic>\n                      spp) are found more often in urine samples of infertile men than in asymptomatic controls and to determine resistance to macrolides.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The study included first void urine samples taken from 145 infertile men and 49 men with no symptoms of urethritis.\n                      <jats:italic>M. genitalium, Chlamydia trachomatis<\/jats:italic>\n                      and\n                      <jats:italic>Neisseria gonorrhoeae<\/jats:italic>\n                      were detected by commercial PCR.\n                      <jats:italic>Trichomonas vaginalis<\/jats:italic>\n                      was detected by microscopy and culture.\n                      <jats:italic>M. hominis<\/jats:italic>\n                      and\n                      <jats:italic>Ureaplasma<\/jats:italic>\n                      spp were detected by culture.\n                      <jats:italic>M. genitalium<\/jats:italic>\n                      was detected by in-house conventional and real-time PCR.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Two\n                      <jats:italic>M. genitalium<\/jats:italic>\n                      positive samples were found among samples obtained from infertile men. All asymptomatic men were\n                      <jats:italic>M. genitalium<\/jats:italic>\n                      negative. Macrolide resistance was not found in either of the two positive samples.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      In comparison with reported data, an unusually low prevalence of\n                      <jats:italic>M. genitalium<\/jats:italic>\n                      was found in infertile men. The reasons for this unexpected result are not known; possibly, local demographic and social characteristics of the population influenced the result. Further studies to investigate\n                      <jats:italic>M. genitalium<\/jats:italic>\n                      in infertile and other groups of patients are needed.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2014-005372","type":"journal-article","created":{"date-parts":[[2014,8,25]],"date-time":"2014-08-25T23:31:37Z","timestamp":1409009497000},"page":"e005372","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":17,"title":["Unusually low prevalence of\n                    <i>Mycoplasma genitalium<\/i>\n                    in urine samples from infertile men and healthy controls: a prevalence study"],"prefix":"10.1136","volume":"4","author":[{"given":"Vanda","family":"Plecko","sequence":"first","affiliation":[{"name":"Department of Clinical and Molecular Microbiology, Clinical Hospital Centre Zagreb and School of Medicine University of Zagreb, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidija","family":"Zele-Starcevic","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Microbiology, Clinical Hospital Centre Zagreb and School of Medicine University of Zagreb, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vesna","family":"Tripkovic","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Microbiology, Clinical Hospital Centre Zagreb and School of Medicine University of Zagreb, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihael","family":"Skerlev","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venerology, Clinical Hospital Centre Zagreb and School of Medicine University of Zagreb, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzana","family":"Ljubojevic","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venerology, Clinical Hospital Centre Zagreb and School of Medicine University of Zagreb, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanja","family":"Plesko","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Microbiology, Clinical Hospital Centre Zagreb and School of Medicine University of Zagreb, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Marekovic","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Microbiology, Clinical Hospital Centre Zagreb and School of Medicine University of Zagreb, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorgen Skov","family":"Jensen","sequence":"additional","affiliation":[{"name":"Mycoplasma Laboratory, Staten's Serum Institute, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2014,8,25]]},"reference":[{"key":"2025121603233717000_4.8.e005372.1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1128\/jcm.29.1.46-50.1991","article-title":"Polymerase chain reaction for detection of Mycoplasma genitalium in clinical samples","volume":"29","author":"Jensen","year":"1991","journal-title":"J Clin 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Genital mycoplasmas. In: Holmes KK Sparling PF Stamm WE ., eds. Sexually transmitted diseases. 4 edn. 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