{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T08:11:06Z","timestamp":1765872666137,"version":"3.48.0"},"reference-count":22,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2016,5,25]]},"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Hypnotics and sedatives, especially benzodiazepines and Z-drugs, are frequently prescribed for longer periods than recommended\u2014in spite of potential risks for patients. Any intervention to improve this situation has to take into account the interplay between different actors, interests and needs. The ultimate goal of this study is to develop\u2014together with the professionals involved\u2014ideas for reducing the use of hypnotics and sedatives and then to implement and evaluate adequate interventions in the hospital and at the primary and secondary care interface.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>The study will take place in a regional hospital in northern Germany and in some general practices in this region. We will collect data from doctors, nurses, patients and a major social health insurer to define the problem from multiple perspectives. These data will be explored and discussed with relevant stakeholders to develop interventions. The interventions will be implemented and, in a final step, evaluated. Both quantitative and qualitative data, including surveys, interviews, chart reviews and secondary analysis of social health insurance data, will be collected to obtain a full understanding of the frequency and the reasons for using hypnotics and sedatives.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>Approval has been granted from the ethics review committee of the University Medical Center G\u00f6ttingen, Germany. Results will be disseminated to researchers, clinicians and policy makers in peer-reviewed journal articles and conference publications. One or more dissemination events will be held locally during continuous professional development events for local professionals, including (but not confined to) the study participants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2016-011908","type":"journal-article","created":{"date-parts":[[2016,8,5]],"date-time":"2016-08-05T22:48:33Z","timestamp":1470437313000},"page":"e011908","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Understanding and reducing the prescription of hypnotics and sedatives at the interface of hospital care and general practice: a protocol for a mixed-methods study"],"prefix":"10.1136","volume":"6","author":[{"given":"Stephanie","family":"Heinemann","sequence":"first","affiliation":[{"name":"Department of General Practice, University Medical Center, G\u00f6ttingen, Germany"},{"name":"Department of Health Sciences, University of Applied Sciences, Fulda, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivien","family":"Wei\u00df","sequence":"additional","affiliation":[{"name":"Department of General Practice, University Medical Center, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kati","family":"Straube","sequence":"additional","affiliation":[{"name":"Department of General Practice, University Medical Center, G\u00f6ttingen, Germany"},{"name":"Department of Geriatrics, Evangelisches Krankenhaus G\u00f6ttingen-Weende, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Nau","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, Evangelisches Krankenhaus G\u00f6ttingen-Weende, G\u00f6ttingen, Germany"},{"name":"Institute of Neuropathology, University Medical Center, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Grimmsmann","sequence":"additional","affiliation":[{"name":"German Health Insurance Medical Service (MDK) Mecklenburg-Vorpommern, Schwerin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Himmel","sequence":"additional","affiliation":[{"name":"Department of General Practice, University Medical Center, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Hummers-Pradier","sequence":"additional","affiliation":[{"name":"Department of General Practice, University Medical Center, G\u00f6ttingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,8,5]]},"reference":[{"key":"2025121600085404000_6.8.e011908.1","first-page":"1","article-title":"The problems of long-term treatment with benzodiazepines and related substances: prescribing practice, epidemiology and the treatment of withdrawal","volume":"112","author":"Jahnsen","year":"2015","journal-title":"Deutsches \u00c4rzteblatt"},{"key":"2025121600085404000_6.8.e011908.2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2014.1763"},{"key":"2025121600085404000_6.8.e011908.3","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1002\/pds.3429","article-title":"Prescribing potentially inappropriate medication (PIM) in Germany's elderly as indicated by the PRISCUS list. 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