{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T03:57:40Z","timestamp":1778126260666,"version":"3.51.4"},"reference-count":27,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2016,9,27]]},"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To compare iron stores in infants born after elective caesarean section (CS) and a 30\u2005s delay of umbilical cord clamping with those born vaginally after early (\u226410\u2005s) or delayed (\u2265180\u2005s) cord clamping.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>Prospective observational study with historical control.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Setting<\/jats:title>\n                  <jats:p>Swedish county hospital.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Population<\/jats:title>\n                  <jats:p>64 infants born after elective CS were compared with a historical control of 166 early clamped and 168 delayed clamped after vaginal birth.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Blood and iron status were measured in blood samples collected at birth, 48\u201396\u2005hours after birth, 4 and 12\u2005months of age.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Primary and secondary outcome measures<\/jats:title>\n                  <jats:p>Ferritin at 4\u2005months of age was the primary outcome, second outcome measures were other indicators of iron status, and haemoglobin, at 4 and 12\u2005months of age, as well as respiratory distress at 1 and 6\u2005hours after birth.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>At 4\u2005months infants born by elective CS had better iron status than those born vaginally subjected to early cord clamping, shown by higher adjusted mean difference of ferritin concentration (39\u2005\u00b5g\/L (95% CI 10 to 60)) and mean cell volume (1.8\u2005fL (95% CI 0.6 to 3.0)); and lower levels of transferrin receptors (\u22120.39\u2005mg\/L (95% CI \u22120.69 to \u22120.08)). No differences were seen between infants born after elective CS and delayed clamped vaginally born infants at 4\u2005months. No differences were found between groups at 12\u2005months of age.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Waiting to clamp the umbilical cord for 30\u2005s after elective CS results in higher iron stores at 4\u2005months of age compared with early cord clamping after vaginal birth, and seems to ensure iron status comparable with those achieved after 180\u2005s delayed cord clamping after vaginal birth.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bmjopen-2016-012995","type":"journal-article","created":{"date-parts":[[2016,11,2]],"date-time":"2016-11-02T22:04:20Z","timestamp":1478124260000},"page":"e012995","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":22,"title":["Elective caesarean: does delay in cord clamping for 30\u2005s ensure sufficient iron stores at 4\u2005months of age? A historical cohort control study"],"prefix":"10.1136","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3972-0457","authenticated-orcid":false,"given":"Ola","family":"Andersson","sequence":"first","affiliation":[{"name":"Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden"},{"name":"Department of Research and Development, Region Halland, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Hellstr\u00f6m-Westas","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magnus","family":"Domell\u00f6f","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Pediatrics, Ume\u00e5 University, Ume\u00e5, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,11,2]]},"reference":[{"key":"2025101811332360000_6.11.e012995.1","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1093\/ajcn\/65.2.425","article-title":"Delayed clamping of the umbilical cord improves hematologic status of Guatemalan infants at 2 mo of age","volume":"65","author":"Grajeda","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"2025101811332360000_6.11.e012995.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68889-2"},{"key":"2025101811332360000_6.11.e012995.3","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d7157"},{"key":"2025101811332360000_6.11.e012995.4","doi-asserted-by":"crossref","unstructured":"McDonald SJ , Middleton P , Dowswell T , et al . 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