{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:10:53Z","timestamp":1767676253244,"version":"3.48.0"},"reference-count":33,"publisher":"BMJ","issue":"7","funder":[{"DOI":"10.13039\/501100018553","name":"Wenzhou Science and Technology Project","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100018553","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Zhejiang science and technology innovation project"},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2017,5,26]]},"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The incidence of lumbar disc degeneration disease has increased in recent years. Lumbar interbody fusion using two unilateral pedicle screws and a translaminar facet screw fixation has advantages of minimal invasiveness and lower costs compared with the traditional methods. Moreover, a method guided by a three-dimensional (3D) navigation template may help us improve the surgical accuracy and the success rate. This is the first randomised study using a 3D navigation template to guide a unilateral lumbar pedicle screw with contralateral translaminar facet screw fixation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>Patients who meet the criteria of the surgery will be randomly divided into experimental groups and control groups by a computer-generated randomisation schedule. We will preoperatively design an individual 3D navigation template using CATIA software and MeditoolCreate. The following primary outcomes will be collected: screw angles compared with the optimal screw trajectories in 3D digital images, length of the wound incision, operative time, intraoperative blood loss and complications. The following secondary outcomes will be collected: visual analogue scale (VAS) for back pain, VAS for leg pain and the Oswestry Disability Index. These parameters will be evaluated on day 1 and then 3, 6, 12 and 24 months postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>The study has been reviewed and approved by the institutional ethics review board of the Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University. The results will be presented at scientific communities and peer-reviewed journals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>ChiCTR-IDR-17010466<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2017-016328","type":"journal-article","created":{"date-parts":[[2017,7,25]],"date-time":"2017-07-25T18:30:26Z","timestamp":1501007426000},"page":"e016328","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["A 3D navigation template for guiding a unilateral lumbar pedicle screw with contralateral translaminar facet screw fixation: a study protocol for multicentre randomised controlled trials"],"prefix":"10.1136","volume":"7","author":[{"given":"Zhen-Xuan","family":"Shao","sequence":"first","affiliation":[{"name":"Department of Spine Surgery, Orthopaedic Hospital, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of the Wenzhou Medical University, The Second Medical School of the Wenzhou Medical University, Zhejiang Spine Center, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"He","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, People\u2019s Hospital of Shaoxing, Zhejiang University Shaoxing Hospital, Shaoxing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shao-Qi","family":"He","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, People\u2019s Hospital of Ruian, The Third Affiliated Hospital of Wenzhou Medical University, Ruian, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng-Lei","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Wenzhou Center Hospital, Dingli Hospital of Wenzhou Medical University, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe-Yu","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Ningbo No. 6 Hospital, Ningbo, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Chao","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Jiaxing Hospital of Zhejiang General Corps of Armed Police Forces, Jiaxing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Fei","family":"Ni","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Orthopaedic Hospital, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of the Wenzhou Medical University, The Second Medical School of the Wenzhou Medical University, Zhejiang Spine Center, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang-Yang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Orthopaedic Hospital, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of the Wenzhou Medical University, The Second Medical School of the Wenzhou Medical University, Zhejiang Spine Center, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai-Min","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Orthopaedic Hospital, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of the Wenzhou Medical University, The Second Medical School of the Wenzhou Medical University, Zhejiang Spine Center, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2017,7,21]]},"reference":[{"key":"2025121223220186000_7.7.e016328.1","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3171\/2014.4.SPINE14271","article-title":"Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. 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