{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T16:51:26Z","timestamp":1789923086502,"version":"4.0.1"},"reference-count":49,"publisher":"BMJ","issue":"8","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2017,7,3]]},"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aims to assess the psychometric properties of the Chinese version of the WHOQOL-HIV BREF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cross-sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Centers for Disease Control and Prevention and infectious disease hospitals in three Chinese provinces.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Sample of 1100 people living with HIV\/AIDS (PLWHA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>We recruited 1100 PLWHA to evaluate their quality of life (QOL) using the WHOQOL-HIV BREF. Of these participants, 57 were randomly selected to repeat the QOL evaluation 2 weeks later.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>The reliability of the WHOQOL-HIV BREF was assessed in terms of its internal consistency and test\u2013retest reliability. The construct, concurrent, convergent, discriminant and known-group validity were also analysed. In addition, the factorial invariance across genders was assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Cronbach\u2019s \u03b1 coefficient for the overall scale was 0.93. Except for the spirituality domain, which had an \u03b1 below 0.70 (0.66), the other five domains showed adequate internal consistency. The test\u2013retest reliability revealed a statistically significant intraclass correlation coefficient of 0.72\u20130.82 (p&lt;0.001). Confirmatory factor analysis found that the six-domain structure produced an acceptable fit to the data. The instrument showed factorial invariance across gender groups. All domains were significantly correlated with the general items and the SF-36 (p&lt;0.01). The correlation coefficients were &gt;0.40 (r=0.40\u20130.67), except for the association between the spirituality domain and two general items (QOL: r=0.33; health status: r=0.36). Subjects with lower CD4 counts had lower scores for all domains (p&lt;0.05). Symptomatic participants had significantly lower scores than asymptomatic participants on the physical, psychological and independence domains (p&lt;0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The WHOQOL-HIV BREF revealed good psychometric characteristics among Chinese PLWHA. These findings offer promising support for the use of the WHOQOL-HIV BREF as a measure of QOL among Chinese PLWHA and in cross-cultural comparative studies on QOL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2017-016382","type":"journal-article","created":{"date-parts":[[2017,8,21]],"date-time":"2017-08-21T20:10:25Z","timestamp":1503346225000},"page":"e016382","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":37,"title":["Psychometric properties of the Chinese version of the WHOQOL-HIV BREF to assess quality of life among people living with HIV\/AIDS: a cross-sectional study"],"prefix":"10.1136","volume":"7","author":[{"given":"Yaxin","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Social Medicine, School of Public Health, China Medical University, Shenyang, 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