{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:54:23Z","timestamp":1764996863110,"version":"3.46.0"},"reference-count":37,"publisher":"BMJ","issue":"8","funder":[{"name":"Norwegian Sudden Infant Death and Stillbirth Society"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2017,6,28]]},"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate whether family history of disease and pregravid lifestyle and cardiovascular risk factors are associated with subsequent stillbirth delivery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prepregnancy cohort study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Cohort Norway regional health surveys (1994\u20132003) linked to Medical Birth Registry of Norway for deliveries through 2012.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>\n                      13 497 singleton births (\n                      <jats:underline>&gt;<\/jats:underline>\n                      22 weeks gestation) in 8478 women.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measure<\/jats:title>\n                    <jats:p>Risk of stillbirth evaluated by Poisson regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean (SD) length of follow-up was 5.5 (3.5) years. In analyses adjusting for baseline age and length of follow-up, \u22653 hours of baseline past-year vigorous physical activity per week (resulting in shortness of breath\/sweating) was associated with increased risk of stillbirth compared with &lt;1\u2009hour\/week of vigorous activity (incidence rate ratio, IRR 2.46; 95%\u2009CI 1.23 to 4.90). In contrast, baseline past-year light physical activity of \u22653 hours per week associated with reduced risk of stillbirth compared with &lt;3\u2009hours of light physical activity per week (IRR 0.53; 95%\u2009CI 0.30 to 0.93). A family history of stroke associated with increased risk of stillbirth delivery (IRR 2.53; 95%\u2009CI 1.06 to 6.01). Because overweight\/obese women may experience shortness of breath and sweating with less physical exertion than normal weight women, a sensitivity analysis was conducted limited to women with a normal BMI (\n                      <jats:underline>&gt;<\/jats:underline>\n                      18.5\u2009and &lt;25\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). Vigorous activity of \u22653 hours per week (IRR of 4.50; 95%\u2009CI 1.72 to 11.79) and a family history of stroke (IRR of 3.81; 95%\u2009CI 1.31 to 11.07) were more strongly related to stillbirth risk among women with a normal BMI than that observed for all women combined. Established risk factors also associated with stillbirth risk.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The study identified physical activity and family history of stroke as potential new risk factors for stillbirth delivery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2017-017034","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T20:25:24Z","timestamp":1502483124000},"page":"e017034","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Association between pregravid physical activity and family history of stroke and risk of stillbirth: population-based cohort study"],"prefix":"10.1136","volume":"7","author":[{"given":"Grace M","family":"Egeland","sequence":"first","affiliation":[{"name":"Department of Global Public Health 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