{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:55:20Z","timestamp":1791327320284,"version":"4.3.1"},"reference-count":81,"publisher":"BMJ","issue":"3","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2018,1,26]]},"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The Nineteen and Up study (19Up) assessed a range of mental health and behavioural problems and associated risk factors in a genetically informative Australian cohort of young adult twins and their non-twin siblings. As such, 19Up enables detailed investigation of genetic and environmental pathways to mental illness and substance misuse within the Brisbane Longitudinal Twin Sample (BLTS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Twins and their non-twin siblings from Queensland, Australia; mostly from European ancestry. Data were collected between 2009 and 2016 on 2773 participants (age range 18\u201338, 57.8% female, 372 complete monozygotic pairs, 493 dizygotic pairs, 640 non-twin siblings, 403 singleton twins).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings to date<\/jats:title>\n                    <jats:p>A structured clinical assessment (Composite International Diagnostic Interview) was used to collect lifetime prevalence of diagnostic statistical manual (4th edition) (DSM-IV) diagnoses of major depressive disorder, (hypo)mania, social anxiety, cannabis use disorder, alcohol use disorder, panic disorder and psychotic symptoms. Here, we further describe the comorbidities and ages of onset for these mental disorders. Notably, two-thirds of the sample reported one or more lifetime mental disorder.<\/jats:p>\n                    <jats:p>In addition, the 19Up study assessed general health, drug use, work activity, education level, personality, migraine\/headaches, suicidal thoughts, attention deficit hyperactivity disorder (ADHD) symptomatology, sleep\u2013wake patterns, romantic preferences, friendships, familial environment, stress, anorexia and bulimia as well as baldness, acne, asthma, endometriosis, joint flexibility and internet use.<\/jats:p>\n                    <jats:p>The overlap with previous waves of the BLTS means that 84% of the 19Up participants are genotyped, 36% imaged using multimodal MRI and most have been assessed for psychological symptoms at up to four time points. Furthermore, IQ is available for 57%, parental report of ADHD symptomatology for 100% and electroencephalography for 30%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Future plans<\/jats:title>\n                    <jats:p>The 19Up study complements a phenotypically rich, longitudinal collection of environmental and psychological risk factors. Future publications will explore hypotheses related to disease onset and development across the waves of the cohort. A follow-up study at 25+years is ongoing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2017-018959","type":"journal-article","created":{"date-parts":[[2018,3,17]],"date-time":"2018-03-17T09:15:11Z","timestamp":1521278111000},"page":"e018959","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":33,"title":["Nineteen and Up study (19Up): understanding pathways to mental health disorders in young Australian twins"],"prefix":"10.1136","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0719-9302","authenticated-orcid":false,"given":"Baptiste","family":"Couvy-Duchesne","sequence":"first","affiliation":[{"name":"Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia"},{"name":"QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"O\u2019Callaghan","sequence":"additional","affiliation":[{"name":"Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Parker","sequence":"additional","affiliation":[{"name":"QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Mills","sequence":"additional","affiliation":[{"name":"Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia"},{"name":"QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia"},{"name":"School of Medicine, University of Adelaide, Adelaide, South Australia, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine M","family":"Kirk","sequence":"additional","affiliation":[{"name":"QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Scott","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre, University of Sydney, Sydney, New South Wales, Australia"},{"name":"Institute of Neuroscience, Newcastle University, Newcastle, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Vinkhuyzen","sequence":"additional","affiliation":[{"name":"Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia"},{"name":"Institute of Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel F","family":"Hermens","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre, University of Sydney, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penelope A","family":"Lind","sequence":"additional","affiliation":[{"name":"QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracey A","family":"Davenport","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre, University of Sydney, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane M","family":"Burns","sequence":"additional","affiliation":[{"name":"Young and Well CRC, University of Melbourne, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Connell","sequence":"additional","affiliation":[{"name":"UQCCR, The University of Queensland, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan P","family":"Zietsch","sequence":"additional","affiliation":[{"name":"QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia"},{"name":"School of Psychology, The University of Queensland, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Scott","sequence":"additional","affiliation":[{"name":"UQCCR, The University of Queensland, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret J","family":"Wright","sequence":"additional","affiliation":[{"name":"Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia"},{"name":"Centre for Advanced Imaging, The University of Queensland, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E","family":"Medland","sequence":"additional","affiliation":[{"name":"QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"McGrath","sequence":"additional","affiliation":[{"name":"Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia"},{"name":"Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas G","family":"Martin","sequence":"additional","affiliation":[{"name":"QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian B","family":"Hickie","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre, University of Sydney, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan A","family":"Gillespie","sequence":"additional","affiliation":[{"name":"QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia"},{"name":"Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,3,17]]},"reference":[{"key":"2025121219372820000_8.3.e018959.1","doi-asserted-by":"publisher","DOI":"10.1017\/thg.2012.111"},{"key":"2025121219372820000_8.3.e018959.2","doi-asserted-by":"publisher","DOI":"10.1080\/00049530410001734865"},{"key":"2025121219372820000_8.3.e018959.3","doi-asserted-by":"publisher","DOI":"10.1023\/A:1013393327704"},{"key":"2025121219372820000_8.3.e018959.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0511(02)00058-3"},{"key":"2025121219372820000_8.3.e018959.5","doi-asserted-by":"publisher","DOI":"10.1023\/A:1013397428612"},{"key":"2025121219372820000_8.3.e018959.6","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291711002431"},{"key":"2025121219372820000_8.3.e018959.7","doi-asserted-by":"publisher","DOI":"10.1375\/1369052012146"},{"key":"2025121219372820000_8.3.e018959.8","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq324"},{"key":"2025121219372820000_8.3.e018959.9","doi-asserted-by":"publisher","DOI":"10.1017\/thg.2015.42"},{"key":"2025121219372820000_8.3.e018959.10","doi-asserted-by":"publisher","DOI":"10.1086\/302494"},{"key":"2025121219372820000_8.3.e018959.11","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2272(1999)16:1<40::AID-GEPI4>3.0.CO;2-1"},{"key":"2025121219372820000_8.3.e018959.12","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1111\/j.0022-202X.2005.23961.x","article-title":"Genetic and environmental influences on skin pattern deterioration","volume":"125","author":"Shekar","year":"2005","journal-title":"J Invest Dermatol"},{"key":"2025121219372820000_8.3.e018959.13","doi-asserted-by":"publisher","DOI":"10.1002\/mpr.168"},{"key":"2025121219372820000_8.3.e018959.14","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2513"},{"key":"2025121219372820000_8.3.e018959.15","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0b013e3283477a09"},{"key":"2025121219372820000_8.3.e018959.16","doi-asserted-by":"crossref","unstructured":"Degenhardt L , Ferrari AJ , Calabria B , et al . The global epidemiology and contribution of cannabis use and dependence to the global burden of disease: results from the GBD 2010 study. PLoS One 2013;8.doi:10.1371\/journal.pone.0076635","DOI":"10.1371\/journal.pone.0076635"},{"key":"2025121219372820000_8.3.e018959.17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2008.02456.x"},{"issue":"Suppl","key":"2025121219372820000_8.3.e018959.18","first-page":"S10","article-title":"Development of a simple screening tool for common mental disorders in general practice","volume":"175","author":"Hickie","year":"2001","journal-title":"Med J Aust"},{"key":"2025121219372820000_8.3.e018959.19","doi-asserted-by":"crossref","first-page":"171","DOI":"10.5694\/j.1326-5377.1999.tb127716.x","article-title":"Primary care psychiatry is not specialist psychiatry in general practice","volume":"170","author":"Hickie","year":"1999","journal-title":"Med J Aust"},{"key":"2025121219372820000_8.3.e018959.20","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1614.2003.01112.x"},{"key":"2025121219372820000_8.3.e018959.21","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S1836-9553(12)70133-9","article-title":"Sphere 12 screening questionnaire","volume":"58","author":"Berryman","year":"2012","journal-title":"J Physiother"},{"key":"2025121219372820000_8.3.e018959.22","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291702006074"},{"key":"2025121219372820000_8.3.e018959.23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.1991.tb01879.x"},{"key":"2025121219372820000_8.3.e018959.24","unstructured":"Swanson J , et al . Categorical and dimensional definitions and evaluations of symptoms of ADHD: The snap and the swan ratings scales. 2005;2014 http:\/\/www.adhd.net\/SNAP_SWAN.pdf"},{"key":"2025121219372820000_8.3.e018959.25","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(96)00548-3"},{"key":"2025121219372820000_8.3.e018959.26","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(89)90047-4"},{"key":"2025121219372820000_8.3.e018959.27","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1093\/sleep\/34.5.601","article-title":"The Insomnia Severity Index: psychometric indicators to detect insomnia cases and evaluate treatment response","volume":"34","author":"Morin","year":"2011","journal-title":"Sleep"},{"key":"2025121219372820000_8.3.e018959.28","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8341.1979.tb02487.x"},{"key":"2025121219372820000_8.3.e018959.29","doi-asserted-by":"publisher","DOI":"10.1017\/S003329170002105X"},{"key":"2025121219372820000_8.3.e018959.30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1990.tb01360.x"},{"key":"2025121219372820000_8.3.e018959.31","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291712000608"},{"key":"2025121219372820000_8.3.e018959.32","doi-asserted-by":"crossref","unstructured":"Eysenck HJ , Eysenck SBG . Manual of the Eysenck Personality Questionnaire (Junior and Adult). (Hodder & Stoughton 1975.","DOI":"10.1037\/t05462-000"},{"key":"2025121219372820000_8.3.e018959.33","doi-asserted-by":"crossref","unstructured":"Costa PT , McCrae RR . The NEO personality inventory manual: Psychological Assessment Resources, 1985.","DOI":"10.1037\/t07564-000"},{"key":"2025121219372820000_8.3.e018959.34","doi-asserted-by":"crossref","unstructured":"Morey LC . Personality assessment inventory, professional manual: Psychological Assessment Resources, Inc, 1991.","DOI":"10.1037\/t03903-000"},{"key":"2025121219372820000_8.3.e018959.35","doi-asserted-by":"crossref","unstructured":"Schmaal L , Hibar DP , S\u00e4mann PG , et al . Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group. Mol Psychiatry 2017;22.doi:10.1038\/mp.2016.60","DOI":"10.1038\/mp.2016.60"},{"key":"2025121219372820000_8.3.e018959.36","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2015.69"},{"key":"2025121219372820000_8.3.e018959.37","doi-asserted-by":"publisher","DOI":"10.1038\/nature15394"},{"key":"2025121219372820000_8.3.e018959.38","doi-asserted-by":"publisher","DOI":"10.1038\/nature15393"},{"key":"2025121219372820000_8.3.e018959.39","doi-asserted-by":"crossref","unstructured":"McCarthy S , Das S , Kretzschmar W , et al . A reference panel of 64,976 haplotypes for genotype imputation. Nat Genet 2016;48.doi:10.1038\/ng.3643","DOI":"10.1038\/ng.3643"},{"key":"2025121219372820000_8.3.e018959.40","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3390"},{"key":"2025121219372820000_8.3.e018959.41","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-008-9029-0"},{"key":"2025121219372820000_8.3.e018959.42","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0912149107"},{"key":"2025121219372820000_8.3.e018959.43","doi-asserted-by":"crossref","first-page":"594-605","DOI":"10.1080\/00048670902970882","article-title":"2007 National Survey of Mental Health and Wellbeing: methods and key findings","volume":"43","author":"Slade","year":"2009","journal-title":"Aust N Z J Psychiatry"},{"key":"2025121219372820000_8.3.e018959.44","doi-asserted-by":"publisher","DOI":"10.1017\/S2045796015000189"},{"key":"2025121219372820000_8.3.e018959.45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2010.05.017"},{"key":"2025121219372820000_8.3.e018959.46","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-9-90"},{"key":"2025121219372820000_8.3.e018959.47","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1614.2006.01905.x"},{"key":"2025121219372820000_8.3.e018959.48","doi-asserted-by":"publisher","DOI":"10.3109\/10398561003731155"},{"key":"2025121219372820000_8.3.e018959.49","doi-asserted-by":"publisher","DOI":"10.3109\/00048674.2011.624083"},{"key":"2025121219372820000_8.3.e018959.50","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0b013e32816ebc8c"},{"key":"2025121219372820000_8.3.e018959.51","doi-asserted-by":"publisher","DOI":"10.1177\/0004867414546699"},{"key":"2025121219372820000_8.3.e018959.52","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2010.09071050"},{"key":"2025121219372820000_8.3.e018959.53","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.32233"},{"key":"2025121219372820000_8.3.e018959.54","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.63.4.415"},{"key":"2025121219372820000_8.3.e018959.55","doi-asserted-by":"crossref","first-page":"614","DOI":"10.15288\/jsad.2013.74.614","article-title":"An evaluation of the proposed DSM-5 cannabis use disorder criteria using Australian national survey data","volume":"74","author":"Mewton","year":"2013","journal-title":"J Stud Alcohol Drugs"},{"key":"2025121219372820000_8.3.e018959.56","doi-asserted-by":"publisher","DOI":"10.1177\/0004867412460591"},{"key":"2025121219372820000_8.3.e018959.57","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291704002922"},{"key":"2025121219372820000_8.3.e018959.58","unstructured":"Welfare, A. I. o. H. a. Drug statistics series no. 27. Canberraz: AIHW, 2011."},{"key":"2025121219372820000_8.3.e018959.59","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1001\/jamapsychiatry.2015.0575","article-title":"Psychotic Experiences in the General Population: A Cross-National Analysis Based on 31,261 Respondents From 18 Countries","volume":"72","author":"McGrath","year":"2015","journal-title":"JAMA Psychiatry"},{"key":"2025121219372820000_8.3.e018959.60","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291712001626"},{"key":"2025121219372820000_8.3.e018959.61","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.185.4.298"},{"key":"2025121219372820000_8.3.e018959.62","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291705006392"},{"key":"2025121219372820000_8.3.e018959.63","doi-asserted-by":"publisher","DOI":"10.1177\/0004867412449877"},{"key":"2025121219372820000_8.3.e018959.64","doi-asserted-by":"crossref","first-page":"901","DOI":"10.3109\/00048674.2010.490520","article-title":"Changes in the prevalence of major depression in an Australian community sample between 1998 and 2008","volume":"44","author":"Goldney","year":"2010","journal-title":"Aust Nz J Psychiat"},{"key":"2025121219372820000_8.3.e018959.65","doi-asserted-by":"publisher","DOI":"10.1080\/00048670902970882"},{"key":"2025121219372820000_8.3.e018959.66","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2008.02.009"},{"key":"2025121219372820000_8.3.e018959.67","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2015.05.031"},{"key":"2025121219372820000_8.3.e018959.68","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbp083"},{"key":"2025121219372820000_8.3.e018959.69","doi-asserted-by":"crossref","unstructured":"McGrath JJ , Saha S , Al-Hamzawi A , et al . The Bidirectional Associations Between Psychotic Experiences and DSM-IV Mental Disorders. Am J Psychiatry 2016;173.doi:10.1176\/appi.ajp.2016.15101293","DOI":"10.1176\/appi.ajp.2016.15101293"},{"key":"2025121219372820000_8.3.e018959.70","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3406"},{"key":"2025121219372820000_8.3.e018959.71","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2711"},{"key":"2025121219372820000_8.3.e018959.72","doi-asserted-by":"publisher","DOI":"10.1151\/spp053113"},{"key":"2025121219372820000_8.3.e018959.73","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2007.01.002"},{"key":"2025121219372820000_8.3.e018959.74","doi-asserted-by":"crossref","unstructured":"Neale MC , Cardon LR . Methodology for genetic studies of twins and families: Kluwer Academic Pub, 1992.","DOI":"10.1007\/978-94-015-8018-2"},{"key":"2025121219372820000_8.3.e018959.75","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.1978.10"},{"key":"2025121219372820000_8.3.e018959.76","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201990"},{"key":"2025121219372820000_8.3.e018959.77","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2010.11.011"},{"key":"2025121219372820000_8.3.e018959.78","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2008.07.006"},{"key":"2025121219372820000_8.3.e018959.79","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12295"},{"key":"2025121219372820000_8.3.e018959.80","doi-asserted-by":"crossref","unstructured":"Rietschel L , Streit F , Zhu G , et al . Hair Cortisol and Its Association With Psychological Risk Factors for Psychiatric Disorders: A Pilot Study in Adolescent Twins. Twin Res Hum Genet 2016 19.doi:10.1017\/thg.2016.50","DOI":"10.1017\/thg.2016.50"},{"key":"2025121219372820000_8.3.e018959.81","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2016.03.008"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2017-018959","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T03:37:40Z","timestamp":1765597060000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2017-018959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":81,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,3,17]]},"published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1136\/bmjopen-2017-018959"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2017-018959","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3]]}}}