{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T03:39:38Z","timestamp":1787629178704,"version":"build-2736575974"},"reference-count":44,"publisher":"BMJ","issue":"6","funder":[{"name":"National Institute for Health Research, School for Primary Care Research"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2018,5,14]]},"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe the prevalence, incidence and surgical management of carpal tunnel syndrome (CTS), between 1993 and 2013, as recorded in the Clinical Practice Research Datalink (CPRD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>We completed a series of cross-sectional epidemiological analyses to observe trends over time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Primary care data collected between 1993 and 2013, stored in the CPRD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>Individuals aged \u226518 years were selected. Prevalent and incident episodes of CTS and episodes of surgical intervention were identified using a list of preidentified Read codes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Analysis<\/jats:title><jats:p>We defined incident episodes as those with no preceding diagnostic code for CTS in the past 2 years of data. Episodes of surgery were expressed as a percentage of the prevalent population during the same calendar year. Joinpoint regression was used to determine significant changes in the underlying trend.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of CTS increased over the study period, with a particular incline between 2000 and 2004 (annual percentage change 7.81). The female-to-male prevalence ratio reduced over time from 2.74 in 1993 to 1.93 in 2013. The median age of females and males with CTS were noted to increase from 49 and 53 years, respectively in 1993 to 54 and 59 years, respectively in 2013. Incidence was also noted to increase over time. After an initial increase between 1993 and 2007, the percentage of prevalent patients with a coded surgical episode began to decrease after 2007 to 27.41% in 2013 (annual percentage change \u22121.7).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study has demonstrated that the prevalence and incidence of CTS increased over the study period between 1993 and 2013. Rates of surgery for CTS also increased over the study period; however after 2007, the per cent of patients receiving surgery showed a statistically significant decline back to the rate seen in 2004.<\/jats:p><\/jats:sec>","DOI":"10.1136\/bmjopen-2017-020166","type":"journal-article","created":{"date-parts":[[2018,6,19]],"date-time":"2018-06-19T15:16:51Z","timestamp":1529421411000},"page":"e020166","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":66,"title":["Trends in the prevalence, incidence and surgical management of carpal tunnel syndrome between 1993 and 2013: an observational analysis of UK primary care records"],"prefix":"10.1136","volume":"8","author":[{"given":"Claire L","family":"Burton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda S","family":"Chesterton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle A","family":"van der Windt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,6,19]]},"reference":[{"key":"2024051711300565000_8.6.e020166.1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-009-0213-9"},{"key":"2024051711300565000_8.6.e020166.2","first-page":"6","article-title":"Carpal tunnel syndrome","volume":"77","author":"Aroori","year":"2008","journal-title":"Ulster Med J"},{"key":"2024051711300565000_8.6.e020166.3","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1212\/WNL.53.8.1654","article-title":"Multiperspective assessment of carpal tunnel syndrome: a multicenter study. 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