{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T09:21:13Z","timestamp":1774516873772,"version":"3.50.1"},"reference-count":46,"publisher":"BMJ","issue":"8","funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2018,7,11]]},"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the relationship between seafood consumption during pregnancy and the risk of delivering a small for gestational age (SGA) newborn.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>This case\u2013control study included women with SGA newborns and controls matched 1:1 for maternal age (\u00b12 years) and hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Five hospitals in Eastern Andalusia, Spain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>518 pairs of pregnant Spanish women. The SGA group included women who delivered SGA newborns: SGA was defined as a birth weight below the 10th percentile of infants at a given gestational age. Controls were women who delivered newborns with adequate birth weights.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>We collected data on demographic characteristics, socioeconomic status, toxic habits and diet. Midwives administered a 137-item Food Frequency Questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome measures<\/jats:title>\n                    <jats:p>We calculated quintiles of seafood intake and applied conditional logistic regression to estimate ORs and 95% CIs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Shellfish intake more than once\/week yielded a significant protective effect against an SGA newborn (OR 0.25, 95%\u2009CI 0.08 to 0.76, after adjusting for energy, educational level, smoking, prepregnancy body mass index, weight and a history of preterm or low birthweight newborn). The risk of an SGA newborn was lower among women who consumed &gt;29\u2009g\/day fish compared with women who consumed \u22648\u2009g (adjusted OR 0.63, 95%\u2009CI 0.41 to 0.98; p=0.025 for a trend). Similarly, the risk of an SGA newborn was lower among women who consumed &gt;1\u2009g\/day of marine n-3 polyunsaturated fatty acids compared with those who consumed \u22640.4\u2009g\/day (adjusted OR 0.58, 95%\u2009CI 0.38 to 0.90; p=0.025 for a trend).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>An average seafood intake of at least 29\u2009g\/day during pregnancy, equivalent to 2\u20133 servings\/week, reduced the risk of an SGA newborn, compared with an average seafood intake of less than 8\u2009g\/day.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2017-020424","type":"journal-article","created":{"date-parts":[[2018,8,18]],"date-time":"2018-08-18T00:05:37Z","timestamp":1534550737000},"page":"e020424","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Maternal seafood intake and the risk of small for gestational age newborns: a case\u2013control study in Spanish women"],"prefix":"10.1136","volume":"8","author":[{"given":"Carmen","family":"Amezcua-Prieto","sequence":"first","affiliation":[{"name":"Department of Preventive Medicine and Public Health, School of Medicine, University of Granada, Granada, Spain"},{"name":"CIBER de Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP, Spain), Madrid, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria de Granada (ibs.Granada), Granada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Miguel","family":"Mart\u00ednez-Galiano","sequence":"additional","affiliation":[{"name":"CIBER de Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP, Spain), Madrid, Spain"},{"name":"Department of Health Sciences, University of Jaen, Ja\u00e9n, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inmaculada","family":"Salcedo-Bellido","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Public Health, School of Medicine, University of Granada, Granada, Spain"},{"name":"CIBER de Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP, Spain), Madrid, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria de Granada (ibs.Granada), Granada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roc\u00edo","family":"Olmedo-Requena","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Public Health, School of Medicine, University of Granada, Granada, Spain"},{"name":"CIBER de Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP, Spain), Madrid, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria de Granada (ibs.Granada), Granada, 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