{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T12:26:42Z","timestamp":1765888002663,"version":"3.48.0"},"reference-count":21,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2018,4,18]]},"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Continuous ambulatory peritoneal dialysis (CAPD) is the ideal modality for renal replacement therapy in most African settings given that it is relatively cheaper than haemodialysis (HD) and does not require in-centre care. CAPD is, however, not readily utilised as it is often complicated by peritonitis leading to high rates of technique failure. The objective of this study is to assess the prevalence of CAPD-related peritonitis and all-cause mortality in patients treated with CAPD in Africa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>\n                      We will search PubMed, EMBASE, SCOPUS, Africa Journal Online and Google Scholar for studies conducted in Africa from 1 January 1980 to 30 June 2017 with no language restrictions. Eligible studies will include cross-sectional, prospective observational and cohort studies of patients treated with CAPD. Two authors will independently screen, select studies, extract data and conduct risk of bias assessment. Data consistently reported across studies will be pooled using random-effects meta-analysis. Heterogeneity will be evaluated using Cochrane\u2019s Q statistic and quantified using I\n                      <jats:sup>2<\/jats:sup>\n                      statistics. Graphical and formal statistical tests will be used to assess for publication bias.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>Ethical approval will not be needed for this study as data used will be extracted from already published studies. Results of this review will be published in a peer-reviewed journal and presented at conferences. The Preferred Reporting Items for Systematic reviews and Meta-Analyses for Protocols 2015 (PRISMA-P 2015) framework guided the development of this protocol.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PROSPERO registration number<\/jats:title>\n                    <jats:p>CRD42017072966.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2017-020464","type":"journal-article","created":{"date-parts":[[2018,5,24]],"date-time":"2018-05-24T13:40:34Z","timestamp":1527169234000},"page":"e020464","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Prevalence of peritonitis and mortality in patients treated with continuous ambulatory peritoneal dialysis (CAPD) in Africa: a protocol for a systematic review and meta-analysis"],"prefix":"10.1136","volume":"8","author":[{"given":"Mothusi Walter","family":"Moloi","sequence":"first","affiliation":[{"name":"Division of Nephrology and Hypertension, University of Cape Town, Cape Town, South Africa"},{"name":"Department of Medicine, Princess Marina Hospital, Gaborone, Botswana"},{"name":"Kidney and Hypertension Research Unit, University of Cape Town, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shepherd","family":"Kajawo","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, University of Cape Town, Cape Town, South Africa"},{"name":"Kidney and Hypertension Research Unit, University of Cape Town, Cape Town, South Africa"},{"name":"Division of Clinical Practice and Patient Care, National University of Science and Technology, Bulawayo, Zimbabwe"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Jacques","family":"Noubiap","sequence":"additional","affiliation":[{"name":"Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikechukwu O","family":"Mbah","sequence":"additional","affiliation":[{"name":"Department of Medicine, Federal Medical Centre, Keffi, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Udeme","family":"Ekrikpo","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, University of Cape Town, Cape Town, South Africa"},{"name":"Kidney and Hypertension Research Unit, University of Cape Town, Cape Town, South Africa"},{"name":"Department of Medicine, University of Uyo, Uyo, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre Pascal","family":"Kengne","sequence":"additional","affiliation":[{"name":"Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa"},{"name":"Non-communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aminu K","family":"Bello","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikechi G","family":"Okpechi","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, University of Cape Town, Cape Town, South Africa"},{"name":"Kidney and Hypertension Research Unit, University of Cape Town, Cape Town, South 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