{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T10:20:21Z","timestamp":1779358821416,"version":"3.51.4"},"reference-count":33,"publisher":"BMJ","issue":"8","funder":[{"name":"Clinical scientific research project of the Second Affiliated Hospital of the Wenzhou Medical University"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2018,7,3]]},"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Arthroscopic-assisted balloon tibioplasty is an emerging technology that has shown advantages in recovering depression of the articular surface. However, studies evaluating clinical outcomes between arthroscopic-assisted balloon tibioplasty and traditional open reduction internal fixation (ORIF) are sparse. This is the first randomised study to compare arthroscopic-assisted balloon tibioplasty with ORIF, and will provide guidance for treating patients with Schatzker types II, III and IV with depression of the medial tibial plateau only.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and analysis<\/jats:title>\n                  <jats:p>A blinded randomised controlled trial will be conducted and a total of 80 participants will be randomly divided into either the arthroscopic-assisted balloon tibioplasty group or the ORIF group, at a ratio of 1:1. The primary clinical outcome measures are the knee functional scores, Rasmussen radiological evaluation scores and the quality of reduction based on postoperative CT scan. Secondary clinical outcome measures are intraoperative blood loss, surgical duration, visual analogue scale score after surgery, hospital duration after surgery, complications and 36-Item Short-Form Health Survey score.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Ethics and dissemination<\/jats:title>\n                  <jats:p>This study has been reviewed and approved by the Institutional Review Board of the Second Affiliated Hospital of Wenzhou Medical University (batch: 2017\u201312). The results will be presented in peer-reviewed journals after completion of the study.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Trial registration number<\/jats:title>\n                  <jats:p>\n                     <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"NCT03327337\" ext-link-type=\"clintrialgov\" specific-use=\"clinicaltrial pre-results\">NCT03327337<\/jats:ext-link>, Pre-results.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bmjopen-2018-021667","type":"journal-article","created":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T03:05:38Z","timestamp":1533783938000},"page":"e021667","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Arthroscopic-assisted balloon tibioplasty versus open reduction internal fixation (ORIF) for treatment of Schatzker II\u2013IV tibial plateau fractures: study protocol of a randomised controlled trial"],"prefix":"10.1136","volume":"8","clinical-trial-number":[{"clinical-trial-number":"nct03327337","registry":"10.18810\/clinical-trials-gov","type":"preResults"},{"clinical-trial-number":"nct03327337","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8437-1209","authenticated-orcid":false,"given":"Ji-Qi","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing-Jie","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Jun","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Jiang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A-Bing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You-Ming","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University, Wenzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,8,8]]},"reference":[{"key":"2025101815013192000_8.8.e021667.1","first-page":"Cd009679","article-title":"Surgical fixation methods for tibial plateau fractures","volume":"240","author":"McNamara","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"2025101815013192000_8.8.e021667.2","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.clinbiomech.2015.05.016","article-title":"Effect of additional fixation in tibial plateau impression fractures treated with balloon reduction and cement augmentation","volume":"30","author":"Mayr","year":"2015","journal-title":"Clin Biomech"},{"key":"2025101815013192000_8.8.e021667.3","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1097\/00003086-199405000-00031","article-title":"Indications for surgical treatment of tibial condyle fractures","volume":"302","author":"Honkonen","year":"1994","journal-title":"Clin Orthop Relat Res"},{"key":"2025101815013192000_8.8.e021667.4","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.injury.2008.01.023","article-title":"The classification systems for tibial plateau fractures: how reliable are they?","volume":"39","author":"Maripuri","year":"2008","journal-title":"Injury"},{"key":"2025101815013192000_8.8.e021667.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2011.03.025"},{"key":"2025101815013192000_8.8.e021667.6","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s13018-016-0427-5","article-title":"The morphological features of different Schatzker types of tibial plateau fractures: a three-dimensional computed tomography study","volume":"11","author":"Chen","year":"2016","journal-title":"J Orthop Surg Res"},{"key":"2025101815013192000_8.8.e021667.7","doi-asserted-by":"crossref","first-page":"3464","DOI":"10.1007\/s00167-014-3256-2","article-title":"Clinical and radiological outcomes following arthroscopic-assisted management of tibial plateau fractures: a systematic review","volume":"23","author":"Chen","year":"2015","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2025101815013192000_8.8.e021667.8","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1097\/BOT.0000000000000892","article-title":"Percutaneous Repair of a Schatzker III Tibial Plateau Fracture Assisted by Arthroscopy","volume":"31 Suppl 3","author":"Egol","year":"2017","journal-title":"J Orthop Trauma"},{"key":"2025101815013192000_8.8.e021667.9","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1007\/s00132-014-3019-2","article-title":"[Minimally invasive treatment of depression fractures of the tibial plateau using balloon repositioning and tibioplasty: video article]","volume":"43","author":"Craiovan","year":"2014","journal-title":"Orthopade"},{"key":"2025101815013192000_8.8.e021667.10","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/j.injury.2016.04.021","article-title":"The extended posterolateral approach for split depression lateral tibial plateau fractures extending into the posterior column: 2 years follow up results of a prospective study","volume":"47","author":"Gavaskar","year":"2016","journal-title":"Injury"},{"key":"2025101815013192000_8.8.e021667.11","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/j.injury.2016.03.024","article-title":"Moore I postero-medial articular tibial fracture in alpine skiers: Surgical management and return to sports activity","volume":"47","author":"Morin","year":"2016","journal-title":"Injury"},{"key":"2025101815013192000_8.8.e021667.12","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s11751-012-0148-1","article-title":"Tibial plateau fractures: compared outcomes between ARIF and ORIF","volume":"7","author":"Dall\u2019oca","year":"2012","journal-title":"Strategies Trauma Limb Reconstr"},{"key":"2025101815013192000_8.8.e021667.13","doi-asserted-by":"crossref","first-page":"e486","DOI":"10.3928\/01477447-20160427-03","article-title":"Arthroscopic-Assisted Fixation of Tibial Plateau Fractures: Patient-Reported Postoperative Activity Levels","volume":"39","author":"Kampa","year":"2016","journal-title":"Orthopedics"},{"key":"2025101815013192000_8.8.e021667.14","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1016\/j.injury.2013.03.013","article-title":"A comparative biomechanical study for complex tibial plateau fractures: nailing and compression bolts versus modern and traditional plating","volume":"44","author":"Lasanianos","year":"2013","journal-title":"Injury"},{"key":"2025101815013192000_8.8.e021667.15","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0b013e31823a8dc8"},{"key":"2025101815013192000_8.8.e021667.16","doi-asserted-by":"crossref","first-page":"411","DOI":"10.4103\/1947-2714.166223","article-title":"Arthroscopy Assisted Balloon Osteoplasty of a Tibia Plateau Depression Fracture: A Case Report","volume":"7","author":"Ziogas","year":"2015","journal-title":"N Am J Med Sci"},{"key":"2025101815013192000_8.8.e021667.17","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s12880-015-0091-y","article-title":"Osseous vitality in single photon emission computed tomography\/computed tomography (SPECT\/CT) after balloon tibioplasty of the tibial plateau: a case series","volume":"15","author":"Jentzsch","year":"2015","journal-title":"BMC Med Imaging"},{"issue":"Suppl 2","key":"2025101815013192000_8.8.e021667.18","doi-asserted-by":"crossref","first-page":"161","DOI":"10.2106\/JBJS.J.00812","article-title":"Combined arthroscopic treatment of tibial plateau and intercondylar eminence avulsion fractures","volume":"92 Suppl 2","author":"Di Caprio","year":"2010","journal-title":"J Bone Joint Surg Am"},{"key":"2025101815013192000_8.8.e021667.19","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1007\/s00264-015-3047-5","article-title":"Balloon tibioplasty for reduction of depressed tibial plateau fractures: Preliminary radiographic and clinical results","volume":"40","author":"Ollivier","year":"2016","journal-title":"Int Orthop"},{"key":"2025101815013192000_8.8.e021667.20","first-page":"31","article-title":"Balloon tibioplasty: pearls and pitfalls","volume":"27","author":"Mauffrey","year":"2014","journal-title":"J Knee Surg"},{"key":"2025101815013192000_8.8.e021667.21","doi-asserted-by":"crossref","first-page":"S61","DOI":"10.1016\/S0020-1383(17)30742-8","article-title":"Tibial plateau fracture management: arthroscopically-assisted versus ORIF procedure - clinical and radiological comparison","volume":"48 Suppl 5","author":"Elabjer","year":"2017","journal-title":"Injury"},{"key":"2025101815013192000_8.8.e021667.22","first-page":"385","article-title":"Proposed definitions for the audit of postoperative infection: a discussion paper. Surgical Infection Study Group","volume":"73","author":"Peel","year":"1991","journal-title":"Ann R Coll Surg Engl"},{"key":"2025101815013192000_8.8.e021667.23","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s10195-015-0372-9","article-title":"External versus internal fixation for bicondylar tibial plateau fractures: systematic review and meta-analysis","volume":"16","author":"Metcalfe","year":"2015","journal-title":"J Orthop Traumatol"},{"key":"2025101815013192000_8.8.e021667.24","doi-asserted-by":"crossref","first-page":"574","DOI":"10.5312\/wjo.v8.i7.574","article-title":"Return to sport following tibial plateau fractures: A systematic review","volume":"8","author":"Robertson","year":"2017","journal-title":"World J Orthop"},{"key":"2025101815013192000_8.8.e021667.25","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2008.04.001"},{"key":"2025101815013192000_8.8.e021667.26","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0b013e31802c5b51"},{"key":"2025101815013192000_8.8.e021667.27","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2014.06.005"},{"key":"2025101815013192000_8.8.e021667.28","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0000000000000203"},{"key":"2025101815013192000_8.8.e021667.29","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2003.09.038"},{"key":"2025101815013192000_8.8.e021667.30","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1016\/j.arthro.2013.05.003","article-title":"Arthroscopy-assisted reduction of posteromedial tibial plateau fractures with buttress plate and cannulated screw construct","volume":"29","author":"Chiu","year":"2013","journal-title":"Arthroscopy"},{"key":"2025101815013192000_8.8.e021667.31","doi-asserted-by":"crossref","unstructured":"Ruiz-Iban MA , Diaz-Heredia J , Elias-Martin E , et al . Cebreiro Martinez Del Val I (2012) Repair of meniscal tears associated with tibial plateau fractures: a review of 15 cases. The American journal of sports medicine;40:2289\u201395.","DOI":"10.1177\/0363546512457552"},{"key":"2025101815013192000_8.8.e021667.32","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200102000-00028"},{"key":"2025101815013192000_8.8.e021667.33","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.jor.2016.12.002","article-title":"Tibioplasty, a new technique in the management of tibial plateau fracture: A multicentric experience review","volume":"14","author":"Doria","year":"2017","journal-title":"J Orthop"}],"container-title":["BMJ Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bmjopen-2018-021667","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T22:01:41Z","timestamp":1760824901000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmjopen.bmj.com\/lookup\/doi\/10.1136\/bmjopen-2018-021667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":33,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2018,8,8]]},"published-print":{"date-parts":[[2018,8]]}},"alternative-id":["10.1136\/bmjopen-2018-021667"],"URL":"https:\/\/doi.org\/10.1136\/bmjopen-2018-021667","relation":{},"ISSN":["2044-6055","2044-6055"],"issn-type":[{"value":"2044-6055","type":"print"},{"value":"2044-6055","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8]]}}}