{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T20:56:54Z","timestamp":1779397014711,"version":"3.53.1"},"reference-count":23,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2018,6,29]]},"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Patients with congestive heart failure (CHF) may be at a higher risk of mortality from sepsis than patients without CHF due to insufficient cardiovascular reserves during systemic infections. The aim of this study is to compare sepsis-related mortality between CHF and no CHF in patients presenting to a tertiary medical centre.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A single-centre, retrospective, cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Conducted in an academic emergency department (ED) between January 2010 and January 2015. Patients\u2019 charts were queried via the hospital\u2019s electronic system. Patients with a diagnosis of sepsis were included. Descriptive analysis was performed on the demographics, characteristics and outcomes of patients with sepsis of the study population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>A total of 174 patients, of which 87 (50%) were patients with CHF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Primary and secondary outcomes<\/jats:title><jats:p>The primary outcome of the study was in-hospital mortality. Secondary outcomes included intensive care unit (ICU) and hospital lengths of stay, and differences in interventions between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients with CHF had a higher in-hospital mortality (57.5% vs 34.5%). Patients with sepsis and CHF had higher odds of death compared with the control population (OR 2.45; 95%\u2009CI 1.22 to 4.88). Secondary analyses showed that patients with CHF had lower instances of bacteraemia on presentation to the ED (31.8% vs 46.4%). They had less intravenous fluid requirements in first 24\u2009hours (2.75\u00b12.28\u2009L vs 3.67\u00b12.82\u2009L, p =0.038), had a higher rate of intubation in the ED (24.2% vs 10.6%, p=0.025) and required more dobutamine in the first 24\u2009hours (16.1% vs 1.1%, p&lt;0.001). ED length of stay was found to be lower in patients with CHF (15.12\u00b124.45\u2009hours vs 18.17\u00b126.13\u2009hours, p=0.418) and they were more likely to be admitted to the ICU (59.8% vs 48.8%, p=0.149).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with sepsis and CHF experienced an increased hospital mortality compared with patients without CHF.<\/jats:p><\/jats:sec>","DOI":"10.1136\/bmjopen-2018-022185","type":"journal-article","created":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T15:20:06Z","timestamp":1533136806000},"page":"e022185","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":27,"title":["Outcomes of patients with systolic heart failure presenting with sepsis to the emergency department of a tertiary hospital: a retrospective chart review study from Lebanon"],"prefix":"10.1136","volume":"8","author":[{"given":"Gilbert","family":"Abou Dagher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Hajjar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Khoury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"El Hajj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Kanso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maha","family":"Makki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelie","family":"Mailhac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralphe","family":"Bou Chebl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,8,1]]},"reference":[{"key":"2024051713013744000_8.7.e022185.1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000350"},{"key":"2024051713013744000_8.7.e022185.2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.113.300268"},{"key":"2024051713013744000_8.7.e022185.3","unstructured":"Centers for Disease Control and Prevention. 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