{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:11:55Z","timestamp":1790665915932,"version":"4.1.0"},"reference-count":34,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2018,11,9]]},"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study was to determine the burden and risk factors of prediabetes and diabetes in the general adult population of Luxembourg.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Cross-sectional survey between 2013 and 2015.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Data were collected as part of the European Health Examination Survey in Luxembourg (EHES-LUX).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>1451 individuals were recruited in a random sample of the 25\u201364-year-old population of Luxembourg.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcomes<\/jats:title>\n                    <jats:p>Diabetes was defined by a glycaemic biomarker (fasting plasma glucose (FPG) \u22657.0\u2009mmol\/L), self-reported medication and medical diagnosis; prediabetes by a glycaemic biomarker (FPG 5.6\u20136.9\u2009mmol\/L), no self-reported medication and no medical diagnosis. Undiagnosed diabetes was defined only from the glycaemic biomarker; the difference between total and undiagnosed diabetes was defined as diagnosed diabetes. Odds of diabetes and prediabetes as well as associated risk factors were estimated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The weighted prevalence of prediabetes and diabetes was 25.6% and 6.5%, respectively. Nearly 4.8% (men: 5.8%; women: 3.8%) were diagnosed diabetes and 1.7% (men: 2.6%; women: 0.7%) were undiagnosed diabetes. The multivariable-adjusted OR (MVOR) for diabetes risk were: age 1.05 (95% CI 1.01 to 1.09), family history of diabetes 3.24 (1.95\u20135.38), abdominal obesity 2.63 (1.53\u20134.52), hypertension 3.18 (1.76\u20135.72), one-unit increase of triglycerides 1.16 (1.10\u20131.22) and total cholesterol 0.74 (0.64\u20130.86). The MVOR for prediabetes risk were: age 1.04 (95% CI 1.02 to 1.06), male sex 1.84 (1.30\u20132.60), moderate alcohol consumption 1.38 (1.01\u20131.89), family history of diabetes 1.52 (1.13\u20132.05), abdominal obesity 1.44 (1.06\u20131.97), second-generation immigrants 0.61 (0.39\u20130.95) and a one-unit increase of serum high-density lipoprotein cholesterol 0.70 (0.54\u20130.90).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In Luxembourg, an unexpectedly high number of adults may be affected by prediabetes and diabetes. Therefore, these conditions should be addressed as a public health priority for the country, requiring measures for enhanced detection and surveillance, which are currently lacking, especially in primary care settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2018-022206","type":"journal-article","created":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T06:52:46Z","timestamp":1548139966000},"page":"e022206","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Public health burden of pre-diabetes and diabetes in Luxembourg: finding from the 2013\u20132015 European Health Examination Survey"],"prefix":"10.1136","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3089-2877","authenticated-orcid":false,"given":"Val\u00e9ry","family":"Bocquet","sequence":"first","affiliation":[{"name":"Competence Centre for Methodology and Statistics, Luxembourg Institute of Health, Strassen, 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