{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T23:08:16Z","timestamp":1781910496905,"version":"3.54.5"},"reference-count":38,"publisher":"BMJ","issue":"3","funder":[{"DOI":"10.13039\/100004334","name":"Merck and Co","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100004334","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2018,12,5]]},"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To estimate self-reported human papillomavirus (HPV) disease-related psychosocial impact among male and female patients in South Korea.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>In this multicentre cross-sectional study, psychosocial impacts were estimated using a one-time survey capturing HPV Impact Profile (HIP) results, CuestionarioEspecifico en Condilomas Acuminados (CECA; in Spanish)\u2014\u2018Specific questionnaire for Condylomata Acuminata\u2019 and the EuroQol-5 Dimension (EQ-5D) surveys. Student\u2019s t-tests or Mann-Whitney U tests were used for continuous comparisons; \u03c7<jats:sup>2<\/jats:sup> or Fisher\u2019s exact tests were applied for categorical comparisons.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Setting<\/jats:title>\n                  <jats:p>5098 clinics throughout Seoul, Busan, Daegu, Kwangju and Daejeon (South Korea).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Participants<\/jats:title>\n                  <jats:p>Patients with and without genital warts (GW) (males) and selected HPV diseases (females) visiting primary care physicians, obstetricians\/gynaecologists, urologists and dermatologists with 2\u201330 years experience.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 150 male and 250 female patients, HIP scores showed 85.3% of male patients with GW and 32.0% without reported moderate psychological impact (p&lt;0.0001). In categorised total scores, 88.5% of female patients with and 66.0% without selected HPV-related diseases reported moderate or high psychological impacts (p=0.0004). In the CECA questionnaire, male patients had mean (SD) scores of 10.51 (3.79) in \u2018emotional health\u2019 and 15.90 (6.13) in \u2018sexual activity\u2019. Female patients with GW reported lower scores in both dimensions with mean scores of 7.18 (4.17) in \u2018emotional health\u2019 and 10.97 (5.80) in \u2018sexual activity\u2019 (p&lt;0.0001), indicating worse health-related quality of life (HRQoL). For the EQ-5D, male patients with GW reported lower mean Visual Analogue Scale (VAS) scores than those without (75.1 vs 81.13, p&lt;0.0135). Mean VAS score and utility values were lower for females with HPV-related diseases than those without (72.18 vs 76.86 and 0.90 vs 0.94, respectively).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In South Korea, GW in men and HPV-related diseases in women negatively impact patient well-being and HRQoL scores. Among women, those with GW suffered a greater psychosocial impact than those with other selected HPV-related diseases.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/bmjopen-2018-025035","type":"journal-article","created":{"date-parts":[[2019,3,21]],"date-time":"2019-03-21T05:39:40Z","timestamp":1553146780000},"page":"e025035","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":21,"title":["Cross-sectional study estimating the psychosocial impact of genital warts and other anogenital diseases in South Korea"],"prefix":"10.1136","volume":"9","author":[{"given":"Taek Sang","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, SMG-SNU Boramae Medical Center, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita","family":"Kothari-Talwar","sequence":"additional","affiliation":[{"name":"Merck and Co Inc, Kenilworth, New Jersey, 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